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Author Details

Zachary Steinhart
Gladstone-UCSF Institute of Genomic Immunology
2015
17
14
Nevan J Krogan (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
36638795An evolved AAV variant enables efficient genetic engineering of murine T cells.Cell2023
35113687CRISPR activation and interference screens decode stimulation responses in primary human T cells.Science2022
36278408SCF<sup>FBXW7</sup> regulates G2-M progression through control of CCNL1 ubiquitination.EMBO Rep2022
32511497Test performance evaluation of SARS-CoV-2 serological assays.medRxiv2020
31881079IPO11 mediates βcatenin nuclear import in a subset of colorectal cancers.J Cell Biol2020
32601235Single-molecule dynamics of Dishevelled at the plasma membrane and Wnt pathway activation.Proc Natl Acad Sci U S A2020
32855547Evaluation of SARS-CoV-2 serology assays reveals a range of test performance.Nat Biotechnol2020
32709883Copper bioavailability is a KRAS-specific vulnerability in colorectal cancer.Nat Commun2020
30995489Genome-Wide CRISPR-Cas9 Screens Expose Genetic Vulnerabilities and Mechanisms of Temozolomide Sensitivity in Glioblastoma Stem Cells.Cell Rep2019
31452509Tailored tetravalent antibodies potently and specifically activate Wnt/Frizzled pathways in cells, organoids and mice.Elife2019
29884654Wnt signaling in development and tissue homeostasis.Development2018
30183492A synthetic anti-Frizzled antibody engineered for broadened specificity exhibits enhanced anti-tumor properties.MAbs2018
27869803Genome-wide CRISPR screens reveal a Wnt-FZD5 signaling circuit as a druggable vulnerability of RNF43-mutant pancreatic tumors.Nat Med2017
29117169Corrigendum: Genome-wide CRISPR screens reveal a Wnt-FZD5 signaling circuit as a druggable vulnerability of RNF43-mutant pancreatic tumors.Nat Med2017
27486244Dishevelled is a NEK2 kinase substrate controlling dynamics of centrosomal linker proteins.Proc Natl Acad Sci U S A2016
27744318Essential role of the Dishevelled DEP domain in a Wnt-dependent human-cell-based complementation assay.J Cell Sci2016
26627737High-Resolution CRISPR Screens Reveal Fitness Genes and Genotype-Specific Cancer Liabilities.Cell2015
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Collaborators

Stephane Angers
Department of Pharmaceutical Sciences, University of Toronto
Co-authored papers 13
Jason Moffat
University of Toronto
Co-authored papers 6
Traver Hart
University of Texas MD Anderson Cancer Center
Co-authored papers 6
Sachdev S Sidhu
School of Pharmacy, University of Waterloo
Co-authored papers 5
Sichun Lin
Department of Pharmaceutical Sciences, University of Toronto
Co-authored papers 3
Graham MacLeod
University of Toronto
Co-authored papers 3
Alexander Marson
Gladstone-UCSF Institute of Genomic Immunology
Co-authored papers 3
Kevin R Brown
College Street, University of Toronto
Co-authored papers 3
Hans Clevers
Princess Maxima Center for Pediatric Oncology
Co-authored papers 2
Cody T Mowery
University of California san francisco
Co-authored papers 2
Jeffrey D Whitman
University of California San Francisco School of Medicine
Co-authored papers 2
Lila A Farrington
University of California san francisco
Co-authored papers 2
Dianna L Ng
Memorial Sloan Kettering Cancer Center
Co-authored papers 2
Charles Y Chiu
University of California-San Francisco
Co-authored papers 2
Justine Levan
University of California San Francisco
Co-authored papers 2
Youjin V Lee
University of Chicago
Co-authored papers 2
Nevan J Krogan (CM4AI)
University of California San Francisco
Co-authored papers 2
Edward T Ryan
Massachusetts General Hospital
Co-authored papers 2
Gregory M Goldgof
University of California san francisco
Co-authored papers 2
Jackie Chan
University of California san francisco
Co-authored papers 2
Mary E Moreno
San Francisco General Hospital, University of California
Co-authored papers 2
Antonia E Gallman
Yale University School of Medicine
Co-authored papers 2
Trisha A Macrae
University of California san francisco
Co-authored papers 2
Eva M Gillis-Buck
University of California san francisco
Co-authored papers 2
Than S Kyaw
University of California san francisco
Co-authored papers 2
Jason G Cyster
University of California san francisco
Co-authored papers 2
Jochen K Lennerz
Massachusetts General Hospital/Harvard Medical School
Co-authored papers 2
Aashish Manglik
Department of Pharmaceutical Chemistry, University of California San Francisco
Co-authored papers 2
Chun Jimmie Ye
University of California san francisco
Co-authored papers 2
Peter B Dirks
The Hospital for Sick Children, University of Toronto
Co-authored papers 2
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