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Author Details

Simon Koplev
Cancer Research UK Cambridge Institute, University of Cambridge
2016
31
18
PMIDPaper TitleJournal TitlePublished Year
37333408Shared and distinct pathways and networks genetically linked to coronary artery disease between human and mouse.bioRxiv2023
37938972Integration of transcriptomes of senescent cell models with multi-tissue patient samples reveals reduced COL6A3 as an inducer of senescence.Cell Rep2023
37986877A spatial human thymus cell atlas mapped to a continuous tissue axis.bioRxiv2023
38060277Shared and distinct pathways and networks genetically linked to coronary artery disease between human and mouse.Elife2023
37771373Systems immunology-based drug repurposing framework to target inflammation in atherosclerosis.Nat Cardiovasc Res2023
37333408Shared and distinct pathways and networks genetically linked to coronary artery disease between human and mouse.bioRxiv2023
38060277Shared and distinct pathways and networks genetically linked to coronary artery disease between human and mouse.Elife2023
37986877A spatial human thymus cell atlas mapped to a continuous tissue axis.bioRxiv2023
37938972Integration of transcriptomes of senescent cell models with multi-tissue patient samples reveals reduced COL6A3 as an inducer of senescence.Cell Rep2023
37771373Systems immunology-based drug repurposing framework to target inflammation in atherosclerosis.Nat Cardiovasc Res2023
34961328Integrative Prioritization of Causal Genes for Coronary Artery Disease.Circ Genom Precis Med2022
35381883Publisher Correction: Transcriptome-wide association study of coronary artery disease identifies novel susceptibility genes.Basic Res Cardiol2022
36276926A mechanistic framework for cardiometabolic and coronary artery diseases.Nat Cardiovasc Res2022
37484062Loss of soluble guanylyl cyclase in platelets contributes to atherosclerotic plaque formation and vascular inflammation.Nat Cardiovasc Res2022
34849613Dynamic changes in chromatin accessibility are associated with the atherogenic transitioning of vascular smooth muscle cells.Cardiovasc Res2022
35175464Transcriptome-wide association study of coronary artery disease identifies novel susceptibility genes.Basic Res Cardiol2022
34961328Integrative Prioritization of Causal Genes for Coronary Artery Disease.Circ Genom Precis Med2022
37484062Loss of soluble guanylyl cyclase in platelets contributes to atherosclerotic plaque formation and vascular inflammation.Nat Cardiovasc Res2022
35381883Publisher Correction: Transcriptome-wide association study of coronary artery disease identifies novel susceptibility genes.Basic Res Cardiol2022
36276926A mechanistic framework for cardiometabolic and coronary artery diseases.Nat Cardiovasc Res2022
34849613Dynamic changes in chromatin accessibility are associated with the atherogenic transitioning of vascular smooth muscle cells.Cardiovasc Res2022
35175464Transcriptome-wide association study of coronary artery disease identifies novel susceptibility genes.Basic Res Cardiol2022
34338228Histone deacetylase 9 promotes endothelial-mesenchymal transition and an unfavorable atherosclerotic plaque phenotype.J Clin Invest2021
33483510An integrative multiomic network model links lipid metabolism to glucose regulation in coronary artery disease.Nat Commun2021
33499648Sex-Stratified Gene Regulatory Networks Reveal Female Key Driver Genes of Atherosclerosis Involved in Smooth Muscle Cell Phenotype Switching.Circulation2021
34338228Histone deacetylase 9 promotes endothelial-mesenchymal transition and an unfavorable atherosclerotic plaque phenotype.J Clin Invest2021
33483510An integrative multiomic network model links lipid metabolism to glucose regulation in coronary artery disease.Nat Commun2021
33499648Sex-Stratified Gene Regulatory Networks Reveal Female Key Driver Genes of Atherosclerosis Involved in Smooth Muscle Cell Phenotype Switching.Circulation2021
32483290Unraveling tumor-immune heterogeneity in advanced ovarian cancer uncovers immunogenic effect of chemotherapy.Nat Genet2020
32483290Unraveling tumor-immune heterogeneity in advanced ovarian cancer uncovers immunogenic effect of chemotherapy.Nat Genet2020
32541024Clonally expanding smooth muscle cells promote atherosclerosis by escaping efferocytosis and activating the complement cascade.Proc Natl Acad Sci U S A2020
32541024Clonally expanding smooth muscle cells promote atherosclerosis by escaping efferocytosis and activating the complement cascade.Proc Natl Acad Sci U S A2020
31059280Systems Pharmacology Identifies an Arterial Wall Regulatory Gene Network Mediating Coronary Artery Disease Side Effects of Antiretroviral Therapy.Circ Genom Precis Med2019
31059280Systems Pharmacology Identifies an Arterial Wall Regulatory Gene Network Mediating Coronary Artery Disease Side Effects of Antiretroviral Therapy.Circ Genom Precis Med2019
31196451Contribution of Gene Regulatory Networks to Heritability of Coronary Artery Disease.J Am Coll Cardiol2019
31196451Contribution of Gene Regulatory Networks to Heritability of Coronary Artery Disease.J Am Coll Cardiol2019
29293502Integration of pan-cancer transcriptomics with RPPA proteomics reveals mechanisms of epithelial-mesenchymal transition.PLoS Comput Biol2018
30360827Macrophage Trafficking, Inflammatory Resolution, and Genomics in Atherosclerosis: JACC Macrophage in CVD Series (Part 2).J Am Coll Cardiol2018
30444878Functional regulatory mechanism of smooth muscle cell-restricted LMOD1 coronary artery disease locus.PLoS Genet2018
30008326CD90 Identifies Adventitial Mesenchymal Progenitor Cells in Adult Human Medium- and Large-Sized Arteries.Stem Cell Reports2018
29719227A Strategy for Discovery of Endocrine Interactions with Application to Whole-Body Metabolism.Cell Metab2018
29531354Multiancestry genome-wide association study of 520,000 subjects identifies 32 loci associated with stroke and stroke subtypes.Nat Genet2018
29752948Functional and transcriptomic insights into pathogenesis of R9C phospholamban mutation using human induced pluripotent stem cell-derived cardiomyocytes.J Mol Cell Cardiol2018
29293502Integration of pan-cancer transcriptomics with RPPA proteomics reveals mechanisms of epithelial-mesenchymal transition.PLoS Comput Biol2018
29199020The Library of Integrated Network-Based Cellular Signatures NIH Program: System-Level Cataloging of Human Cells Response to Perturbations.Cell Syst2018
29794114JCAD, a Gene at the 10p11 Coronary Artery Disease Locus, Regulates Hippo Signaling in Endothelial Cells.Arterioscler Thromb Vasc Biol2018
30008326CD90 Identifies Adventitial Mesenchymal Progenitor Cells in Adult Human Medium- and Large-Sized Arteries.Stem Cell Reports2018
30444878Functional regulatory mechanism of smooth muscle cell-restricted LMOD1 coronary artery disease locus.PLoS Genet2018
30360827Macrophage Trafficking, Inflammatory Resolution, and Genomics in Atherosclerosis: JACC Macrophage in CVD Series (Part 2).J Am Coll Cardiol2018
29752948Functional and transcriptomic insights into pathogenesis of R9C phospholamban mutation using human induced pluripotent stem cell-derived cardiomyocytes.J Mol Cell Cardiol2018
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Collaborators

Jason C Kovacic
Co-authored papers 12
Aldons J Lusis
Co-authored papers 8
Heribert Schunkert
Co-authored papers 6
Ke Hao
Co-authored papers 6
Eric E Schadt
Icahn School of Medicine at Mount Sinai
Co-authored papers 6
Chiara Giannarelli
Co-authored papers 5
Avi Ma'ayan
Icahn School of Medicine at Mount Sinai
Co-authored papers 5
Clint L Miller
University of Virginia
Co-authored papers 4
Letizia Amadori
Co-authored papers 4
Sherry L Jenkins
Department of Pharmacological Sciences, Icahn School of Medicine at Mount Sinai
Co-authored papers 3
Sander M Houten
Co-authored papers 3
Kathleen M Jagodnik
Massachusetts General Hospital Department of Psychiatry, Harvard Medical School.
Co-authored papers 3
Mete Civelek
Center for Public Health Genomics, University of Virginia
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Alexander Lachmann
Co-authored papers 2
Maxim V Kuleshov
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Stanford University School of Medicine
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Arya Ajay
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Valentin Fuster
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Jeanette Erdmann
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Stephan C Sch??rer
Institute for Data Science and Computing, University of Miami
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Zhidong Tu
Co-authored papers 2
Nicolas F Fernandez
Co-authored papers 2
Anders B Dohlman
Co-authored papers 2
Kathryn J Moore
Co-authored papers 2
James G Wilson
Beth Israel Deaconess Medical Center
Co-authored papers 1
Rick J Koch
Co-authored papers 1
John Danesh
Co-authored papers 1
Ken Sakurai
Co-authored papers 1
Ron Margolis
National Institutes of Health
Co-authored papers 1
Release 1.2