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Author Details

Michael Brenowitz
Albert Einstein College of Medicine
1979
138
44
Andrej Sali (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
34986360Best Practices for Aggregate Quantitation of Antibody Therapeutics by Sedimentation Velocity Analytical Ultracentrifugation.J Pharm Sci2022
33980829INI1/SMARCB1 Rpt1 domain mimics TAR RNA in binding to integrase to facilitate HIV-1 replication.Nat Commun2021
35004218DNA methylation and hydroxymethylation analysis using a high throughput and low bias direct injection mass spectrometry platform.MethodsX2021
34538324High throughput and low bias DNA methylation and hydroxymethylation analysis by direct injection mass spectrometry.Anal Chim Acta2021
32587972Characterization of the SARS-CoV-2 S Protein: Biophysical, Biochemical, Structural, and Antigenic Analysis.bioRxiv2020
33458462Characterization of the SARS-CoV-2 S Protein: Biophysical, Biochemical, Structural, and Antigenic Analysis.ACS Omega2020
30543161Chemical Generation of Hydroxyl Radical for Oxidative 'Footprinting'.Protein Pept Lett2019
31890962Conformational and lipid bilayer-perturbing properties of Marburg virus GP2 segments containing the fusion loop and membrane-proximal external region/transmembrane domain.Heliyon2019
30957488Ca(II) and Zn(II) Cooperate To Modulate the Structure and Self-Assembly of S100A12.Biochemistry2019
29261291Structures of the L27 Domain of Disc Large Homologue 1 Protein Illustrate a Self-Assembly Module.Biochemistry2018
29263320Dynamic intramolecular regulation of the histone chaperone nucleoplasmin controls histone binding and release.Nat Commun2017
27539380Bright monomeric near-infrared fluorescent proteins as tags and biosensors for multiscale imaging.Nat Commun2016
27671238An Opportunity for Industry-Academia Partnership: Training the Next Generation of Industrial Researchers in Characterizing Higher Order Protein Structure.J Pharm Sci2016
27420643MeCP2 Binding Cooperativity Inhibits DNA Modification-Specific Recognition.Biochemistry2016
25786917Structural and Functional Studies on the Marburg Virus GP2 Fusion Loop.J Infect Dis2015
26475863Assembly and Molecular Architecture of the Phosphoinositide 3-Kinase p85α Homodimer.J Biol Chem2015
26173259Different inhibition of Gβγ-stimulated class IB phosphoinositide 3-kinase (PI3K) variants by a monoclonal antibody. Specific function of p101 as a Gβγ-dependent regulator of PI3Kγ enzymatic activity.Biochem J2015
25658332Conditional trimerization and lytic activity of HIV-1 gp41 variants containing the membrane-associated segments.Biochemistry2015
25666234Protein footprinting by pyrite shrink-wrap laminate.Lab Chip2015
24570482An RNA aptamer possessing a novel monovalent cation-mediated fold inhibits lysozyme catalysis by inhibiting the binding of long natural substrates.RNA2014
24828757Unusual characteristics of the DNA binding domain of epigenetic regulatory protein MeCP2 determine its binding specificity.Biochemistry2014
24586236Mapping the kinetic barriers of a Large RNA molecule's folding landscape.PLoS One2014
23528092Understanding the role of three-dimensional topology in determining the folding intermediates of group I introns.Biophys J2013
24252706Structure of the S100A4/myosin-IIA complex.BMC Struct Biol2013
23451136Structure of the arginine methyltransferase PRMT5-MEP50 reveals a mechanism for substrate specificity.PLoS One2013
23426875Conformational heterogeneity of the protein-free human spliceosomal U2-U6 snRNA complex.RNA2013
22215810Spatial arrangement of an RNA zipcode identifies mRNAs under post-transcriptional control.Genes Dev2012
22842460Pyrite footprinting of RNA.Biochem Biophys Res Commun2012
21300286Decoy strategies: the structure of TL1A:DcR3 complex.Structure2011
22025107Monitoring equilibrium changes in RNA structure by 'peroxidative' and 'oxidative' hydroxyl radical footprinting.J Vis Exp2011
21985704Entropy-driven binding of picomolar transition state analogue inhibitors to human 5'-methylthioadenosine phosphorylase.Biochemistry2011
21840113Introduction: twenty five years of the Gibbs Conference on Biothermodynamics.Biophys Chem2011
21863183A microfluidic device that generates hydroxyl radicals to probe the solvent accessible surface of nucleic acids.Lab Chip2011
21605934Stability, denaturation and refolding of Mycobacterium tuberculosis MfpA, a DNA mimicking protein that confers antibiotic resistance.Biophys Chem2011
21712400RNA molecules with conserved catalytic cores but variable peripheries fold along unique energetically optimized pathways.RNA2011
20421509Phenothiazines inhibit S100A4 function by inducing protein oligomerization.Proc Natl Acad Sci U S A2010
20108972Conformational states of human purine nucleoside phosphorylase at rest, at work, and with transition state analogues.Biochemistry2010
19273107Evolutionary and biophysical relationships among the papillomavirus E2 proteins.Front Biosci (Landmark Ed)2009
19426806Complementing global measures of RNA folding with local reports of backbone solvent accessibility by time resolved hydroxyl radical footprinting.Methods2009
19522538Biochemical and structural characterization of the human TL1A ectodomain.Biochemistry2009
19119852PEGylation of Val-1(alpha) destabilizes the tetrameric structure of hemoglobin.Biochemistry2009
18182486Evolution of GITRL immune function: murine GITRL exhibits unique structural and biochemical properties within the TNF superfamily.Proc Natl Acad Sci U S A2008
18772866Semiautomated and rapid quantification of nucleic acid footprinting and structure mapping experiments.Nat Protoc2008
18926923Energy barriers, pathways, and dynamics during folding of large, multidomain RNAs.Curr Opin Chem Biol2008
18977756Solution structure and refolding of the Mycobacterium tuberculosis pentapeptide repeat protein MfpA.J Biol Chem2008
18471829Hinge stiffness is a barrier to RNA folding.J Mol Biol2008
18477638High-throughput single-nucleotide structural mapping by capillary automated footprinting analysis.Nucleic Acids Res2008
18606810Function and structural organization of Mot1 bound to a natural target promoter.J Biol Chem2008
18274531Monitoring structural changes in nucleic acids with single residue spatial and millisecond time resolution by quantitative hydroxyl radical footprinting.Nat Protoc2008
17964944Following molecular transitions with single residue spatial and millisecond time resolution.Methods Cell Biol2008
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Collaborators

Case Western Reserve University
Co-authored papers 21
Albert Einstein College of Medicine
Co-authored papers 14
University of North Carolina at Chapel Hill
Co-authored papers 8
Lawrence Berkeley National Laboratory
Co-authored papers 6
Poornaprajna Institute of Scientific Research (PPISR)
Co-authored papers 6
Stanford University
Co-authored papers 5
Albert Einstein College of Medicine
Co-authored papers 4
Cornell University
Co-authored papers 4
Albert Einstein College of Medicine
Co-authored papers 3
Co-authored papers 3
Co-authored papers 3
Medical College of Wisconsin and Marquette University
Co-authored papers 3
Albert Einstein College of Medicine
Co-authored papers 3
Stanford University
Co-authored papers 2
New York University Grossman School of Medicine
Co-authored papers 2
Dana-Farber Cancer Institute
Co-authored papers 2
The Fenway Institute
Co-authored papers 2
Albert Einstein College of Medicine
Co-authored papers 2
Co-authored papers 2
Stanford University School of Medicine
Co-authored papers 2
University of Virginia
Co-authored papers 2
Yale University, USA Howard Hughes Medical Institute
Co-authored papers 2
Columbia University
Co-authored papers 2
Co-authored papers 2
Albert Einstein College of Medicine
Co-authored papers 2
Albert Einstein College of Medicine, Montefiore Medical Center
Co-authored papers 2
Lawrence Berkeley National Laboratory
Co-authored papers 2
Albert Einstein College of Medicine
Co-authored papers 1
Institute for Computational Biomedicine
Co-authored papers 1
New York University (NYU) Langone Health
Co-authored papers 1