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Author Details

Michelle R Downes
University of Toronto
2006
68
19
PMIDPaper TitleJournal TitlePublished Year
37246824International Society of Urological Pathology (ISUP) Consensus Conference on Current Issues in Bladder Cancer. Working Group 1: Comparison of Bladder Cancer Grading System Performance.Am J Surg Pathol2024
37919231Engineering the future of 3D pathology.J Pathol Clin Res2024
37558528Addition of Cribriform and Intraductal Carcinoma Presence to Prostate Biopsy Reporting Strengthens Pretreatment Risk Stratification Using CAPRA and NCCN Tools.Clin Genitourin Cancer2024
37548751Redefining and capturing pre-analytic deficiencies in an anatomical pathology laboratory: a quality improvement initiative.Virchows Arch2024
37284047International Opinions on Grading of Urothelial Carcinoma: A Survey Among European Association of Urology and International Society of Urological Pathology Members.Eur Urol Open Sci2023
37546794Prostate Cancer Reshapes the Secreted and Extracellular Vesicle Urinary Proteomes.bioRxiv2023
37680023ABCC2 brush-border expression predicts outcome in papillary renal cell carcinoma: a multi-institutional study of 254 cases.Histopathology2023
35466737The Search for the Optimal cut-off Value of p53-Immunohistochemistry to Predict Prognosis of Invasive Bladder Cancer: A Multi-Center, Multi-Laboratory Analysis.Int J Surg Pathol2023
35816346Morphologic Pattern, Frequency, and Spatial Distribution of Lymphovascular Invasion Foci in Radical Prostatectomy Specimens.Int J Surg Pathol2023
34103388Three-antibody classifier for muscle invasive urothelial carcinoma and its correlation with p53 expression.J Clin Pathol2022
35676330Impact of cribriform pattern 4 and intraductal prostatic carcinoma on National Comprehensive Cancer Network (NCCN) and Cancer of Prostate Risk Assessment (CAPRA) patient stratification.Mod Pathol2022
36230835Development of a Clinically Applicable NanoString-Based Gene Expression Classifier for Muscle-Invasive Bladder Cancer Molecular Stratification.Cancers (Basel)2022
35074179The impact of grading scheme on non-muscle invasive bladder cancer progression: potential utility of hybrid grading schemes.Pathology2022
34878188Prevalence of adverse pathology features in grade group 2 prostatectomy specimens with syn- or metachronous metastatic disease.Prostate2022
35027623Upregulation of IFNÉ£-mediated chemokines dominate the immune transcriptome of muscle-invasive urothelial carcinoma.Sci Rep2022
34812724Target prostate biopsies: How best to report in synoptic format?Can Urol Assoc J2022
32471889Immune gene expression profiles in high-grade urothelial carcinoma of the bladder: a NanoString study.J Clin Pathol2021
34509050Development of a multiplex immuno-oncology biomarker and digital pathology workflow for assessment of urothelial carcinoma.Pathol Res Pract2021
34453155Proteomic discovery of non-invasive biomarkers of localized prostate cancer using mass spectrometry.Nat Rev Urol2021
34152685A proteomic investigation of isogenic radiation resistant prostate cancer cell lines.Proteomics Clin Appl2021
33172830Immune cell profiling in Gleason 9 prostate cancer patients treated with brachytherapy versus external beam radiotherapy: An exploratory study.Radiother Oncol2021
33077335Cribriform architecture prostatic adenocarcinoma in needle biopsies is a strong independent predictor for lymph node metastases in radical prostatectomy.Eur J Cancer2021
33175216The impact of pre-analytical parameters on class II biomarkers by immunohistochemistry: concordance across four tissue processing protocols.Virchows Arch2021
31161221Temporal Stability and Prognostic Biomarker Potential of the Prostate Cancer Urine miRNA Transcriptome.J Natl Cancer Inst2020
31874245miR-191 promotes radiation resistance of prostate cancer through interaction with RXRA.Cancer Lett2020
31919144Correlation of mismatch repair protein deficiency, PD-L1 and CD8 expression in high-grade urothelial carcinoma of the bladder.J Clin Pathol2020
32861170Reassessment of p53 immunohistochemistry thresholds in invasive high grade bladder cancer shows a better correlation with TP53 and FGFR3 mutations.Pathol Res Pract2020
33022560Can immune markers help identify fast relapse in patients with muscle invasive bladder cancer?Pathol Res Pract2020
32188330A Practical Approach to Investigating Cross-Contaminants in the Anatomical Pathology Laboratory.Int J Surg Pathol2020
31243779Inter- and intraobserver agreement of programmed death ligand 1 scoring in head and neck squamous cell carcinoma, urothelial carcinoma and breast carcinoma.Histopathology2020
31485721Evaluation of cancer testis antigen (CT10, PRAME) and MHC I expression in high-grade urothelial carcinoma of the bladder.Virchows Arch2020
30694165Value of Increasing Biopsy Cores per Target with Cognitive MRI-targeted Transrectal US Prostate Biopsy.Radiology2019
30160779Concordance of biopsy and prostatectomy diagnosis of intraductal and cribriform carcinoma in a prospectively collected data set.Histopathology2019
31381885Integrated Molecular Analysis of Papillary Renal Cell Carcinoma and Precursor Lesions Unfolds Evolutionary Process from Kidney Progenitor-Like Cells.Am J Pathol2019
31177561Gleason grade patterns in nodal metastasis and corresponding prostatectomy specimens: impact on patient outcome.Histopathology2019
31322262MicroRNAâ¿¿198 suppresses prostate tumorigenesis by targeting MIB1.Oncol Rep2019
31043833A Canadian guideline on the use of next-generation sequencing in oncology.Curr Oncol2019
28768702Tumour front inflammation and necrosis are independent prognostic predictors in high-grade urothelial carcinoma of the bladder.J Clin Pathol2018
30075156Reproducibility of PD-L1 immunohistochemistry interpretation across various types of genitourinary and head/neck carcinomas, antibody clones, and tissue types.Hum Pathol2018
29962847Harmonization of PD-L1 testing in oncology: a Canadian pathology perspective.Curr Oncol2018
29896907Modulating ATP binding cassette transporters in papillary renal cell carcinoma type 2 enhances its response to targeted molecular therapy.Mol Oncol2018
30257853Immune infiltrates and PD-L1 expression in treatment-naïve acinar prostatic adenocarcinoma: an exploratory analysis.J Clin Pathol2018
29947424Basal-subtype bladder tumours show a 'hot' immunophenotype.Histopathology2018
29776013Prognostic pathological factors in radical cystectomy after neoadjuvant chemotherapy.Histopathology2018
29750666PD-L1 Immunohistochemistry Assay Concordance in Urothelial Carcinoma of the Bladder and Hypopharyngeal Squamous Cell Carcinoma.Am J Surg Pathol2018
27530957Analysis of papillary urothelial carcinomas of the bladder with grade heterogeneity: supportive evidence for an early role of CDKN2A deletions in the FGFR3 pathway.Histopathology2017
28342221p53 immunohistochemistry in high-grade urothelial carcinoma of the bladder is prognostically significant.Histopathology2017
28984673Toward Biological Subtyping of Papillary Renal Cell Carcinoma With Clinical Implications Through Histologic, Immunohistochemical, and Molecular Analysis.Am J Surg Pathol2017
28756619Prostate carcinoma with amphicrine features: further refining the spectrum of neuroendocrine differentiation in tumours of primary prostatic origin?Histopathology2017
27993699Gastroesophageal Mucosal Injury after Cholecystectomy: An Indication for Surveillance?J Am Coll Surg2017
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Collaborators

University Health Network, University of Toronto
Co-authored papers 22
Odette Cancer Centre, University of Toronto
Co-authored papers 17
University of Toronto, Canada Odette Cancer Centre
Co-authored papers 15
University of Toronto
Co-authored papers 8
University of Toronto
Co-authored papers 6
University of California los angeles
Co-authored papers 6
McGill University Health Centre, McGill University
Co-authored papers 5
Princess Margaret Cancer Centre, University Health Network and University of Toronto
Co-authored papers 5
Princess Margaret Cancer Center, University Health Network.
Co-authored papers 5
Princess Margaret Hospital
Co-authored papers 4
Princess Margaret Hospital, University of Toronto
Co-authored papers 3
Sunnybrook Research Institute, University of Toronto
Co-authored papers 3
University of Edinburgh
Co-authored papers 3
Ontario Institute for Cancer Research
Co-authored papers 3
Co-authored papers 3
Princess Margaret Cancer Centre, University Health Network, University of Toronto
Co-authored papers 3
Memorial Sloan Kettering Cancer Center
Co-authored papers 3
Ontario Institute for Cancer Research
Co-authored papers 3
University of Toronto, University Health Network
Co-authored papers 2
Princess Margaret Cancer Centre
Co-authored papers 2
St. Michael's Hospital, University of Toronto
Co-authored papers 2
University of Toronto
Co-authored papers 2
Eastern Virginia Medical School
Co-authored papers 2
Eastern Virginia Medical School
Co-authored papers 2
Margaret Cancer Center
Co-authored papers 2
University Health Network
Co-authored papers 2
Evaluative Clinical Sciences, Sunnybrook Research Institute
Co-authored papers 2
UCD Conway Institute, University College Dublin
Co-authored papers 2
Margaret Cancer Center
Co-authored papers 2
Institut du cancer de Montreal
Co-authored papers 2