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Author Details

Keith Syson Chan
Samuel Oschin Cancer Center, Cedars Sinai Medical Center
2000
40
24
PMIDPaper TitleJournal TitlePublished Year
35195258Understanding Drug Sensitivity and Tackling Resistance in Cancer.Cancer Res2022
35347124Cell death-induced immunogenicity enhances chemoimmunotherapeutic response by converting immune-excluded into T-cell inflamed bladder tumors.Nat Commun2022
35764795The dynamic roles of the bladder tumour microenvironment.Nat Rev Urol2022
35718227Dual Stromal Targeting Sensitizes Pancreatic Adenocarcinoma for Anti-Programmed Cell Death Protein 1 Therapy.Gastroenterology2022
35618577Characterizing molecular subtypes of high-risk non-muscle-invasive bladder cancer in African American patients.Urol Oncol2022
36433954circCsnk1g3- and circAnkib1-regulated interferon responses in sarcoma promote tumorigenesis by shaping the immune microenvironment.Nat Commun2022
35918812Discoidin Domain Receptor-Driven Gene Signatures as Markers of Patient Response to Anti-PD-L1 Immune Checkpoint Therapy.J Natl Cancer Inst2022
35031545Cabozantinib plus Nivolumab Phase I Expansion Study in Patients with Metastatic Urothelial Carcinoma Refractory to Immune Checkpoint Inhibitor Therapy.Clin Cancer Res2022
34541033Loss of CDCP1 triggers FAK activation in detached prostate cancer cells.Am J Clin Exp Urol2021
33821233Inhibitory DAMPs in immunogenic cell death and its clinical implications.Cell Stress2021
34400221RNF144A deficiency promotes PD-L1 protein stabilization and carcinogen-induced bladder tumorigenesis.Cancer Lett2021
33335285Integrative multi-omics analysis of muscle-invasive bladder cancer identifies prognostic biomarkers for frontline chemotherapy and immunotherapy.Commun Biol2020
32024545Plasminogen activator inhibitor-2 (PAI-2) overexpression supports bladder cancer development in PAI-1 knockout mice in N-butyl-N- (4-hydroxybutyl)-nitrosamine- induced bladder cancer mouse model.J Transl Med2020
32037144Reply To Kenneth B. Yatai, Mark J. Dunning, Dennis Wang. Consensus Genomic Subtypes of Muscle-invasive Bladder Cancer: A Step in the Right Direction but Still a Long Way To Go. Eur Urol 2020;77:434-5.Eur Urol2020
31086186Collagen-rich airway smooth muscle cells are a metastatic niche for tumor colonization in the lung.Nat Commun2019
31905599Prognostic Significance of Lymphocyte Infiltration and a Stromal Immunostaining of a Bladder Cancer Associated Diagnostic Panel in Urothelial Carcinoma.Diagnostics (Basel)2019
28541380A fully Bayesian latent variable model for integrative clustering analysis of multi-type omics data.Biostatistics2018
29342309Prognostic Power of a Tumor Differentiation Gene Signature for Bladder Urothelial Carcinomas.J Natl Cancer Inst2018
28235762Cellular Hierarchy as a Determinant of Tumor Sensitivity to Chemotherapy.Cancer Res2017
27376123Bladder Cancer Molecular Taxonomy: Summary from a Consensus Meeting.Bladder Cancer2016
26671994Molecular Pathways: Targeting Cancer Stem Cells Awakened by Chemotherapy to Abrogate Tumor Repopulation.Clin Cancer Res2016
27655672Positive association of collagen type I with non-muscle invasive bladder cancer progression.Oncotarget2016
25470039Blocking PGE2-induced tumour repopulation abrogates bladder cancer chemoresistance.Nature2015
25313057RUNX1 is essential for mesenchymal stem cell proliferation and myofibroblast differentiation.Proc Natl Acad Sci U S A2014
22308455Three differentiation states risk-stratify bladder cancer into distinct subtypes.Proc Natl Acad Sci U S A2012
22890301Normal and neoplastic urothelial stem cells: getting to the root of the problem.Nat Rev Urol2012
22532166Stat3 activation in urothelial stem cells leads to direct progression to invasive bladder cancer.Cancer Res2012
20657288Cancer stem cells in bladder cancer: a revisited and evolving concept.Curr Opin Urol2010
18576943Imaging of STAT3 signaling pathway during mouse embryonic stem cell differentiation.Stem Cells Dev2009
19666525Identification, molecular characterization, clinical prognosis, and therapeutic targeting of human bladder tumor-initiating cells.Proc Natl Acad Sci U S A2009
17700521Forced expression of a constitutively active form of Stat3 in mouse epidermis enhances malignant progression of skin tumors induced by two-stage carcinogenesis.Oncogene2008
17601706Impact of Stat3 activation upon skin biology: a dichotomy of its role between homeostasis and diseases.J Dermatol Sci2008
17610223Signal transducer and activator of transcription 3 (Stat3) in epithelial carcinogenesis.Mol Carcinog2007
16603078Active Stat3 is required for survival of human squamous cell carcinoma cells in serum-free conditions.Mol Cancer2006
15592573Stat3 links activated keratinocytes and immunocytes required for development of psoriasis in a novel transgenic mouse model.Nat Med2005
15994947Signal transducer and activator of transcription 3 is a key regulator of keratinocyte survival and proliferation following UV irradiation.Cancer Res2005
15059889Epidermal growth factor receptor-mediated activation of Stat3 during multistage skin carcinogenesis.Cancer Res2004
15343391Disruption of Stat3 reveals a critical role in both the initiation and the promotion stages of epithelial carcinogenesis.J Clin Invest2004
11585718Constitutive expression of ErbB-2 in gallbladder epithelium results in development of adenocarcinoma.Cancer Res2001
10980598Constitutive expression of erbB2 in epidermis of transgenic mice results in epidermal hyperproliferation and spontaneous skin tumor development.Oncogene2000
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Collaborators

Jing Xiao
The University of Texas M.D. Anderson Cancer Center
Co-authored papers 5
Jianjun Shen
The University of Texas MD Anderson Cancer Center
Co-authored papers 4
David J McConkey
Johns Hopkins School of Medicine
Co-authored papers 3
Minhyung Kim
Roswell Park Comprehensive Cancer Center
Co-authored papers 3
Sungyong You
Cedars-Sinai Medical Center
Co-authored papers 3
Francisco X Real
Spanish National Cancer Research Centre-CNIO
Co-authored papers 2
Dolores Di Vizio
Cedars-Sinai Medical Center
Co-authored papers 2
Katherine A Hoadley
Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill
Co-authored papers 2
Stephen J Freedland
Cedars-Sinai Medical Center
Co-authored papers 2
Matthew D Galsky
Co-authored papers 2
Erica Lay
Co-authored papers 2
Clarice S Groeneveld
CNRS, Institut Curie, PSL Research University, Universite Paris Cite
Co-authored papers 1
Brian J Druker
Oregon Health & Science University
Co-authored papers 1
Cai Huang
Markey Cancer Center, University of Kentucky 789 South Limestone St
Co-authored papers 1
Jie-Fu Chen
Memorial Sloan Kettering Cancer Center
Co-authored papers 1
Javier Mariscal
Samuel Oschin Comprehensive Cancer Institute
Co-authored papers 1
Sung Yun Jung
Co-authored papers 1
Ronglai Shen
Co-authored papers 1
Yunfeng Dai
Colleges of Medicine, University of Florida
Co-authored papers 1
Jaegil Kim
Co-authored papers 1
Mauro A A Castro
Federal University of Parana
Co-authored papers 1
Susan G Hilsenbeck
Co-authored papers 1
Andrew H Beck
Beth Israel Deaconess Medical Center, Harvard Medical School
Co-authored papers 1
Jie J Zheng
Molecular Biology Institute, University of California los angeles
Co-authored papers 1
David Spetzler
Co-authored papers 1
Colin P Dinney
The University of Texas MD Anderson Cancer Center
Co-authored papers 1
Howard Y Chang
Center for Personal Dynamic Regulomes, Stanford University
Co-authored papers 1
Sara Pollan
Cedars-Sinai Medical Center 8700 Beverly Blvd
Co-authored papers 1
Olga Rasorenova
University of California Irvine Irvine
Co-authored papers 1
Alex B Blair
Johns Hopkins University School of Medicine
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Release 1.2