Author details

Full Name

Tommi H Nyr??nen

Affiliation

CSC - IT Center for Science Ltd

ORCID

Career Start Year

1999

Papers

H Index

Expertise

CM4AI Collaborator

PMID	Paper Title	Journal Title	Published Year
34820659	The Data Use Ontology to streamline responsible access to human biomedical datasets.	Cell Genom	2021
35072136	GA4GH: International policies and standards for data sharing across genomic research and healthcare.	Cell Genom	2021
34820660	GA4GH Passport standard for digital identity and access permissions.	Cell Genom	2021
31455890	Leveraging European infrastructures to access 1 million human genomes by 2022.	Nat Rev Genet	2019
31520075	Author Correction: Leveraging European infrastructures to access 1 million human genomes by 2022.	Nat Rev Genet	2019
31405382	The bio.tools registry of software tools and data resources for the life sciences.	Genome Biol	2019
30069064	Registered access: authorizing data access.	Eur J Hum Genet	2018
30254736	Common ELIXIR Service for Researcher Authentication and Authorisation.	F1000Res	2018
28330491	Orchestrating differential data access for translational research: a pilot implementation.	BMC Med Inform Decis Mak	2017
26157454	Future opportunities and trends for e-infrastructures and life sciences: going beyond the grid to enable life science data analysis.	Front Genet	2015
24971633	Glucuronidation converts clopidogrel to a strong time-dependent inhibitor of CYP2C8: a phase II metabolite as a perpetrator of drug-drug interactions.	Clin Pharmacol Ther	2014
23194423	Computational and functional analysis of the androgen receptor antagonist atraric acid and its derivatives.	Anticancer Agents Med Chem	2013
23803301	Best practices in bioinformatics training for life scientists.	Brief Bioinform	2013
23742982	iAnn: an event sharing platform for the life sciences.	Bioinformatics	2013
22110242	Bioinformatics Training Network (BTN): a community resource for bioinformatics trainers.	Brief Bioinform	2012
20562256	Bioinformatics training: a review of challenges, actions and support requirements.	Brief Bioinform	2010
22823968	Structural basis for computational screening of non-steroidal androgen receptor ligands.	Expert Opin Drug Discov	2010
18712859	Computationally identified novel diphenyl- and phenylpyridine androgen receptor antagonist structures.	J Chem Inf Model	2008
17447751	Small molecule designed to target metal binding site in the alpha2I domain inhibits integrin function.	J Med Chem	2007
16562991	SOMA--workflow for small molecule property calculations on a multiplatform computing grid.	J Chem Inf Model	2006
16821785	Docking and three-dimensional quantitative structure-activity relationship (3D QSAR) analyses of nonsteroidal progesterone receptor ligands.	J Med Chem	2006
16509586	Molecular evolution of adrenoceptors and dopamine receptors: implications for the binding of catecholamines.	J Med Chem	2006
15715462	Three-dimensional structure-activity relationships of nonsteroidal ligands in complex with androgen receptor ligand-binding domain.	J Med Chem	2005
15943481	BRUTUS: optimization of a grid-based similarity function for rigid-body molecular superposition. 1. Alignment and virtual screening applications.	J Med Chem	2005
15866736	Model structures of alpha-2 adrenoceptors in complex with automatically docked antagonist ligands raise the possibility of interactions dissimilar from agonist ligands.	J Struct Biol	2005
15154745	Comparing the quality and predictiveness between 3D QSAR models obtained from manual and automated alignment.	J Chem Inf Comput Sci	2004
15566299	An in silico approach to discovering novel inhibitors of human sirtuin type 2.	J Med Chem	2004
15663001	BODIL: a molecular modeling environment for structure-function analysis and drug design.	J Comput Aided Mol Des	2004
12556518	Mitochondrial targeting of normal and mutant protoporphyrinogen oxidase.	J Biol Chem	2003
15124929	A structure-activity relationship study of catechol-O-methyltransferase inhibitors combining molecular docking and 3D QSAR methods.	J Comput Aided Mol Des	2003
12970108	Molecular mechanisms of ligand-receptor interactions in transmembrane domain V of the alpha2A-adrenoceptor.	Br J Pharmacol	2003
12473122	Determinants of antagonist binding at the alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptor subunit, GluR-D. Role of the conserved arginine 507 and glutamate 727 residues.	Eur J Biochem	2002
11306720	Molecular mechanism for agonist-promoted alpha(2A)-adrenoceptor activation by norepinephrine and epinephrine.	Mol Pharmacol	2001
10531352	"RKKH" peptides from the snake venom metalloproteinase of Bothrops jararaca bind near the metal ion-dependent adhesion site of the human integrin alpha(2) I-domain.	J Biol Chem	1999
10438518	Three-dimensional models of alpha(2A)-adrenergic receptor complexes provide a structural explanation for ligand binding.	J Biol Chem	1999

1 - 35 of 35

Joel Karpiak

Department of Pharmaceutical Sciences, University of California San Francisco

Career Start Year 2009

Number of shared co-authors 0

Scott J Lusher

Center for Molecular & Biomolecular Informatics, Radboud University Medical Center

Career Start Year 2006

Number of shared co-authors 6

Suwen Zhao

ShanghaiTech University, China iHuman Institute

Career Start Year 2006

Number of shared co-authors 0

Jens Carlsson

Uppsala University

Career Start Year 2004

Number of shared co-authors 0

Gerald H Lushington

Inc. 16 Dekalb Pike

Career Start Year 2002

Number of shared co-authors 0

Anna Gaulton

European Bioinformatics Institute (EMBL-EBI)

Career Start Year 2002

Number of shared co-authors 9

William H Bisson

Knight Cancer Institute, Oregon Health & Science University

Career Start Year 2001

Number of shared co-authors 0

Christopher J Langmead

Monash University

Career Start Year 2000

Number of shared co-authors 0

Nevena Veljkovic

Heliant Ltd

Career Start Year 1999

Number of shared co-authors 3

Stephan C Sch??rer

Institute for Data Science and Computing, University of Miami

Career Start Year 1998

Number of shared co-authors 4

David Lagorce

INSERM

Career Start Year 1998

Number of shared co-authors 7

Peter Kolb

Institut fur Pharmazeutische Chemie, Philipps-Universitat Marburg

Career Start Year 1996

Number of shared co-authors 0

S??ndor Szalma

Takeda California Inc.

Career Start Year 1995

Number of shared co-authors 0

Andrew L Hopkins

University of Dundee

Career Start Year 1995

Number of shared co-authors 1

Cristian G Bologa

University of New Mexico School of Medicine

Career Start Year 1995

Number of shared co-authors 6

Hualiang Jiang

Shanghai Institute of Materia Medica, Chinese Academy of Sciences

Career Start Year 1994

Number of shared co-authors 0

Tudor I Oprea

Expert Systems Inc.

Career Start Year 1993

Number of shared co-authors 6

Robert Preissner

Institute for Physiology, Charite-University Medicine Berlin

Career Start Year 1990

Number of shared co-authors 0

Howard Broughton

Lilly Research Laboratories

Career Start Year 1990

Number of shared co-authors 0

John P Overington

Institute of Cardiovascular Science, University College London

Career Start Year 1988

Number of shared co-authors 6

Herman W T van Vlijmen

Leiden Academic Centre for Drug Research (LACDR), Leiden University

Career Start Year 1988

Number of shared co-authors 4

Andrew R Leach

European Bioinformatics Institute (EMBL-EBI)

Career Start Year 1987

Number of shared co-authors 4

Diane Joseph-McCarthy

Boston University

Career Start Year 1987

Number of shared co-authors 0

Antonio Macchiarulo

Department of Pharmaceutical Sciences, University of Perugia

Career Start Year 1986

Number of shared co-authors 0

Terry R Stouch

Lexicon Pharmaceuticals

Career Start Year 1983

Number of shared co-authors 2

Ferran Sanz

Hospital del Mar Medical Research Institute (IMIM), Pompeu Fabra University

Career Start Year 1982

Number of shared co-authors 21

Russ B Altman

Stanford University

Career Start Year 1982

Number of shared co-authors 9

Ruben Abagyan

Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California

Career Start Year 1981

Number of shared co-authors 1

Christine Humblet

Lilly Research Laboratories

Career Start Year 1977

Number of shared co-authors 2

Jens Meiler

Vanderbilt University

Career Start Year 1954

Number of shared co-authors 4

row(s) 1 - 30 of 30

Mark S Johnson

Abo Akademi University

Co-authored papers 9

Mikael Linden

CSC - IT Center for Science Ltd

Co-authored papers 6

Ilkka Lappalainen

European Bioinformatics Institute

Co-authored papers 5

Rafael C Jimenez

European Bioinformatics Institute

Co-authored papers 5

Jordi Rambla

Universitat Pompeu Fabra

Co-authored papers 5

Nicola Mulder

University of Cape Town

Co-authored papers 4

Michael Baudis

University of Zurich

Co-authored papers 4

Petr Holub

Institute of Computer Science, Masaryk University

Co-authored papers 4

Paul Flicek

European Bioinformatics Institute

Co-authored papers 4

Stephanie O M Dyke

Montreal Neurological Institute, McGill University

Co-authored papers 4

Javier De Las Rivas

Cancer Research Centre (IBMCC/CSIC/USAL/IBSAL)

Co-authored papers 4

Alfonso Valencia

Josep Carreras Leukaemia Research Institute (IJC)

Co-authored papers 4

Anthony A Philippakis

Broad Institute of Harvard and the Massachusetts Institute of Technology

Co-authored papers 4

Helen Parkinson

European Bioinformatics Institute

Co-authored papers 4

Susheel Varma

European Bioinformatics Institute (EMBL-EBI)

Co-authored papers 4

John D Spalding

European Bioinformatics Institute

Co-authored papers 4

Gary Saunders

European Bioinformatics Institute (EMBL-EBI)

Co-authored papers 4

Teresa K Attwood

Co-authored papers 4

Serena Scollen

Pfizer Ltd

Co-authored papers 4

Niklas Blomberg

Universitat Tubingen, Institut fur Arbeitsmedizin

Co-authored papers 3

Moran N Cabili

Foundation Medicine Inc.

Co-authored papers 3

Anthony J Brookes

University of Leicester

Co-authored papers 3

Jaime M Guidry Auvil

National Cancer Institute

Co-authored papers 3

Peter Goodhand

Ontario Institute for Cancer Research

Co-authored papers 3

Angela Page

Broad Institute

Co-authored papers 3

Laura Lyman Rodriguez

Patient-Centered Outcomes Research Institute

Co-authored papers 3

Martin Kuba

Masaryk University

Co-authored papers 3

Giselle Kerry

European Bioinformatics Institute

Co-authored papers 3

Thomas M Keane

European Bioinformatics Institute

Co-authored papers 3

S??ren Brunak

Novo Nordisk Foundation Center for Protein Research, University of Copenhagen

Co-authored papers 3

1 - 30

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