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Author Details

Dieter Weichenhan
German Cancer Research Center (DKFZ)
1988
127
39
PMIDPaper TitleJournal TitlePublished Year
36632736TAL1 activation in T-cell acute lymphoblastic leukemia: a novel oncogenic 3' neo-enhancer.Haematologica2023
37885041Predictive value of DNA methylation patterns in AML patients treated with an azacytidine containing induction regimen.Clin Epigenetics2023
36949154Translocation t(6;7) in AML-M4 cell line GDM-1 results in MNX1 activation through enhancer-hijacking.Leukemia2023
37143403High-resolution transcriptomic and epigenetic profiling identifies novel regulators of COPD.EMBO J2023
36402192Loss of SUV420H2-Dependent Chromatin Compaction Drives Right-Sided Colon Cancer Progression.Gastroenterology2023
36939901Indirect epigenetic testing identifies a diagnostic signature of cardiomyocyte DNA methylation in heart failure.Basic Res Cardiol2023
36704932Global hypomethylation in childhood asthma identified by genome-wide DNA-methylation sequencing preferentially affects enhancer regions.Allergy2023
32822861Epigenomic technologies for precision oncology.Semin Cancer Biol2022
35468210MEOX2 homeobox gene promotes growth of malignant gliomas.Neuro Oncol2022
36070377Pronounced sequence specificity of the TET enzyme catalytic domain guides its cellular function.Sci Adv2022
35931677Club cells employ regeneration mechanisms during lung tumorigenesis.Nat Commun2022
36026441Transcriptional regulation of the thymus master regulator <i>Foxn1</i>.Sci Immunol2022
36287637Global DNA Methylation Analysis of Cancer-Associated Fibroblasts Reveals Extensive Epigenetic Rewiring Linked with RUNX1 Upregulation in Breast Cancer Stroma.Cancer Res2022
35247900Identification and Targeting of the Developmental Blockade in Extranodal Natural Killer/T-cell Lymphoma.Blood Cancer Discov2022
35239184Selective inhibitors of bromodomain BD1 and BD2 of BET proteins modulate radiation-induced profibrotic fibroblast responses.Int J Cancer2022
33468537Integrative analysis reveals early and distinct genetic and epigenetic changes in intraductal papillary and tubulopapillary cholangiocarcinogenesis.Gut2022
33203699Decitabine Induces Gene Derepression on Monosomic Chromosomes: <i>In Vitro</i> and <i>In Vivo</i> Effects in Adverse-Risk Cytogenetics AML.Cancer Res2021
34764283Epigenetic reprogramming of airway macrophages promotes polarization and inflammation in muco-obstructive lung disease.Nat Commun2021
34718742ID3 promotes homologous recombination via non-transcriptional and transcriptional mechanisms and its loss confers sensitivity to PARP inhibition.Nucleic Acids Res2021
34070078Epigenetic Modulation of Radiation-Induced Diacylglycerol Kinase Alpha Expression Prevents Pro-Fibrotic Fibroblast Response.Cancers (Basel)2021
34098582MicroRNA-497/195 is tumor suppressive and cooperates with CDKN2A/B in pediatric acute lymphoblastic leukemia.Blood2021
33197445Diabetes changes gene expression but not DNA methylation in cardiac cells.J Mol Cell Cardiol2021
33060108Aggressive PDACs Show Hypomethylation of Repetitive Elements and the Execution of an Intrinsic IFN Program Linked to a Ductal Cell of Origin.Cancer Discov2021
33100132AmpliconDesign - an interactive web server for the design of high-throughput targeted DNA methylation assays.Epigenetics2021
32272161Genome-Wide DNA Methylation Profiling in Early Stage I Lung Adenocarcinoma Reveals Predictive Aberrant Methylation in the Promoter Region of the Long Noncoding RNA PLUT: An Exploratory Study.J Thorac Oncol2020
31871210Identification of Ppar<i>γ</i>-modulated miRNA hubs that target the fibrotic tumor microenvironment.Proc Natl Acad Sci U S A2020
32005851Neuronal ensemble-specific DNA methylation strengthens engram stability.Nat Commun2020
33110075Globally altered epigenetic landscape and delayed osteogenic differentiation in H3.3-G34W-mutant giant cell tumor of bone.Nat Commun2020
30615206Integrative Analysis Defines Distinct Prognostic Subgroups of Intrahepatic Cholangiocarcinoma.Hepatology2019
30171030Fetal hemoglobin induction during decitabine treatment of elderly patients with high-risk myelodysplastic syndrome or acute myeloid leukemia: a potential dynamic biomarker of outcome.Haematologica2019
30779037Generation of Whole Genome Bisulfite Sequencing Libraries from Very Low DNA Input.Methods Mol Biol2019
31012487Longitudinal trends of serum IgE and IL5RA expression throughout childhood are associated with asthma but not with persistent wheeze.Allergy2019
31064978DNA methylation signatures of monozygotic twins clinically discordant for multiple sclerosis.Nat Commun2019
31135957Somatic mutations and promotor methylation of the ryanodine receptor 2 is a common event in the pathogenesis of head and neck cancer.Int J Cancer2019
30962454Rbpj expression in regulatory T cells is critical for restraining T<sub>H</sub>2 responses.Nat Commun2019
30664630Enhancer hijacking activates oncogenic transcription factor NR4A3 in acinic cell carcinomas of the salivary glands.Nat Commun2019
28921505NFATC1 activation by DNA hypomethylation in chronic lymphocytic leukemia correlates with clinical staging and can be inhibited by ibrutinib.Int J Cancer2018
30537516Molecular Evolution of Early-Onset Prostate Cancer Identifies Molecular Risk Markers and Clinical Trajectories.Cancer Cell2018
28392331Maternal phthalate exposure promotes allergic airway inflammation over 2 generations through epigenetic modifications.J Allergy Clin Immunol2018
29749927The transcriptomic and epigenetic map of vascular quiescence in the continuous lung endothelium.Elife2018
29633898Reactivation of endogenous retroviral elements via treatment with DNMT- and HDAC-inhibitors.Cell Cycle2018
29374152Distinct epigenetic programs regulate cardiac myocyte development and disease in the human heart in vivo.Nat Commun2018
29233739Early-onset childhood atopic dermatitis is related to NLRP2 repression.J Allergy Clin Immunol2018
29224141Tagmentation-Based Library Preparation for Low DNA Input Whole Genome Bisulfite Sequencing.Methods Mol Biol2018
28838933Epigenome-Wide Association Study Identifies Cardiac Gene Patterning and a Novel Class of Biomarkers for Heart Failure.Circulation2017
28100914TET-mediated hydroxymethylcytosine at the Pparγ locus is required for initiation of adipogenic differentiation.Int J Obes (Lond)2017
28344890Suppression of indoleamine-2,3-dioxygenase 1 expression by promoter hypermethylation in ER-positive breast cancer.Oncoimmunology2017
29074949Erratum: DNMT and HDAC inhibitors induce cryptic transcription start sites encoded in long terminal repeats.Nat Genet2017
29144491Corrigendum: Genome-wide DNA-methylation landscape defines specialization of regulatory T cells in tissues.Nat Immunol2017
28783152Genome-wide DNA-methylation landscape defines specialization of regulatory T cells in tissues.Nat Immunol2017
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Collaborators

German Cancer Research Center
Co-authored papers 84
Berlin Institute of Health (BIH) and Charite
Co-authored papers 18
Catholic University (KU) Leuven
Co-authored papers 15
German Cancer Research Center (DKFZ)
Co-authored papers 14
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Co-authored papers 10
University of Augsburg
Co-authored papers 9
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Co-authored papers 8
Berlin Institute of Health at Charite - Universitatsmedizin Berlin
Co-authored papers 8
Institute of Pathology, University Hospital Heidelberg
Co-authored papers 7
University Hospital Regensburg
Co-authored papers 7
German Cancer Research Center (DKFZ)
Co-authored papers 6
German Cancer Research Center
Co-authored papers 5
German Cancer Research Center (DKFZ)
Co-authored papers 5
German Cancer Research Center (DKFZ)
Co-authored papers 4
Co-authored papers 3
Institute of Pathology, University Hospital Heidelberg
Co-authored papers 3
Co-authored papers 3
Co-authored papers 3
German Cancer Research Center (DKFZ)
Co-authored papers 3
Co-authored papers 3
Co-authored papers 3
Co-authored papers 3
Hopp Children's Cancer Center Heidelberg (KiTZ)
Co-authored papers 3
Institute of Pathology, University Hospital Heidelberg
Co-authored papers 3
Center for Genetics, Children's Hospital Oakland Research Institute
Co-authored papers 3
Max Planck Institute for Molecular Genetics
Co-authored papers 3
University Hospital and University of Zurich
Co-authored papers 2
German Cancer Research Center (DKFZ)
Co-authored papers 2
Technical University
Co-authored papers 2
Max-Planck-Institute for Molecular Genetics
Co-authored papers 2