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Author Details

Shixin Liu
The Rockefeller University
2006
45
21
PMIDPaper TitleJournal TitlePublished Year
36711595Structure and DNA bridging activity of the essential Rec114â⿬"Mei4 trimer interface.bioRxiv2023
37595555Catalytic and non-catalytic mechanisms of histone H4 lysine 20 methyltransferase SUV420H1.Mol Cell2023
36993485Catalytic and non-catalytic mechanisms of histone H4 lysine 20 methyltransferase SUV420H1.bioRxiv2023
36945399Incomplete transcripts dominate the <i>Mycobacterium tuberculosis</i> transcriptome.bioRxiv2023
37442580Structure and DNA-bridging activity of the essential Rec114-Mei4 trimer interface.Genes Dev2023
37242904Thermal Conductivity of Polyvinylidene Fluoride Films with a Multi-Scale Framework.Polymers (Basel)2023
37333354Differential dynamics specify MeCP2 function at methylated DNA and nucleosomes.bioRxiv2023
36917983Head-on and co-directional RNA polymerase collisions orchestrate bidirectional transcription termination.Mol Cell2023
35147499The MIDAS domain of AAA mechanoenzyme Mdn1 forms catch bonds with two different substrates.Elife2022
35810158Chromatin sequesters pioneer transcription factor Sox2 from exerting force on DNA.Nat Commun2022
35484234Single-stranded nucleic acid binding and coacervation by linker histone H1.Nat Struct Mol Biol2022
36418314Smc5/6's multifaceted DNA binding capacities stabilize branched DNA structures.Nat Commun2022
36215487Origin recognition complex harbors an intrinsic nucleosome remodeling activity.Proc Natl Acad Sci U S A2022
35999198Nucleosome-directed replication origin licensing independent of a consensus DNA sequence.Nat Commun2022
36063325Probing the Interaction Between Chromatin and Chromatin-Associated Complexes with Optical Tweezers.Methods Mol Biol2022
35923103Mechanical regulation of the helicase activity of Zika virus NS3.Biophys J2022
36263752Solution processed, vertically stacked hetero-structured diodes based on liquid-exfoliated WS<sub>2</sub> nanosheets: from electrode-limited to bulk-limited behavior.Nanoscale2022
33340543Force-dependent stimulation of RNA unwinding by SARS-CoV-2 nsp13 helicase.Biophys J2021
34849486Optical tweezers in single-molecule biophysics.Nat Rev Methods Primers2021
34057467Cooperative DNA looping by PRC2 complexes.Nucleic Acids Res2021
32458799Characterization of the kinetic cycle of an ABC transporter by single-molecule and cryo-EM analyses.Elife2020
33208532Single-molecule and in silico dissection of the interaction between Polycomb repressive complex 2 and chromatin.Proc Natl Acad Sci U S A2020
32766580Force-dependent stimulation of RNA unwinding by SARS-CoV-2 nsp13 helicase.bioRxiv2020
30503774Dynamics of Cas10 Govern Discrimination between Self and Non-self in Type III CRISPR-Cas Immunity.Mol Cell2019
31348887Replication Fork Activation Is Enabled by a Single-Stranded DNA Gate in CMG Helicase.Cell2019
31484078Nonreciprocal and Conditional Cooperativity Directs the Pioneer Activity of Pluripotency Transcription Factors.Cell Rep2019
31308523Full-length RNA profiling reveals pervasive bidirectional transcription terminators in bacteria.Nat Microbiol2019
31251042A Tour de Force on the Double Helix: Exploiting DNA Mechanics To Study DNA-Based Molecular Machines.Biochemistry2019
30867295Using a system's equilibrium behavior to reduce its energy dissipation in nonequilibrium processes.Proc Natl Acad Sci U S A2019
30894531Reversible histone glycation is associated with disease-related changes in chromatin architecture.Nat Commun2019
29436555Ultra-broadband nonlinear optical response of two-dimensional h-BN nanosheets and their hybrid gel glasses.Nanoscale2018
30012596Molecular switch-like regulation enables global subunit coordination in a viral ring ATPase.Proc Natl Acad Sci U S A2018
27844435Deciphering the Molecular Mechanism of the Bacteriophage Ͽ29 DNA Packaging Motor.Methods Mol Biol2017
25597693Protein denaturation at a single-molecule level: the effect of nonpolar environments and its implications on the unfolding mechanism by proteases.Nanoscale2015
25686273Design and synthesis of novel xyloketal derivatives and their protective activities against H2O2-induced HUVEC injury.Mar Drugs2015
24766813A viral packaging motor varies its DNA rotation and step size to preserve subunit coordination as the capsid fills.Cell2014
24806916Mechanical operation and intersubunit coordination of ring-shaped molecular motors: insights from single-molecule studies.Biophys J2014
24066225Complete dissection of transcription elongation reveals slow translocation of RNA polymerase II in a linear ratchet mechanism.Elife2013
24351912Synthesis and neuroprotective action of xyloketal derivatives in Parkinson's disease models.Mar Drugs2013
23178121High degree of coordination and division of labor among subunits in a homomeric ring ATPase.Cell2012
20547794Structure-activity analysis of vinylogous urea inhibitors of human immunodeficiency virus-encoded ribonuclease H.Antimicrob Agents Chemother2010
21102446Initiation complex dynamics direct the transitions between distinct phases of early HIV reverse transcription.Nat Struct Mol Biol2010
19008444Slide into action: dynamic shuttling of HIV reverse transcriptase on nucleic acid substrates.Science2008
17496145Dissecting the multistep reaction pathway of an RNA enzyme by single-molecule kinetic "fingerprinting".Proc Natl Acad Sci U S A2007
16872630Two distinct binding modes of a protein cofactor with its target RNA.J Mol Biol2006
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Collaborators

University of California berkeley
Co-authored papers 8
The Rockefeller University
Co-authored papers 5
Howard Hughes Medical Institute, Harvard University
Co-authored papers 5
The Rockefeller University
Co-authored papers 4
Massachusetts Institute of Technology
Co-authored papers 3
Tri-Institutional PhD Program in Chemical Biology
Co-authored papers 3
The Rockefeller University
Co-authored papers 2
Howard Hughes Medical Institute, The Rockefeller University
Co-authored papers 2
The Rockefeller University
Co-authored papers 2
The Rockefeller University
Co-authored papers 2
University of California san francisco
Co-authored papers 2
Brain and Mind Research Institute
Co-authored papers 2
Massachusetts Institute of Technology
Co-authored papers 2
Center for Eukaryotic Gene Regulation, Pennsylvania State University, University Park
Co-authored papers 2
The Rockefeller University
Co-authored papers 2
Tri-Institutional MD-PhD Program
Co-authored papers 1
The Rockefeller University
Co-authored papers 1
Tri-Institutional PhD Program in Chemical Biology
Co-authored papers 1
The Rockefeller University
Co-authored papers 1
Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center (MSKCC)
Co-authored papers 1
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University of Texas Medical Branch
Co-authored papers 1
Massachusetts Institute of Technology, University of California, San Francisco, University of Notre Dame
Co-authored papers 1
Tri-Institutional PhD Program in Chemical Biology
Co-authored papers 1
Memorial Sloan-Kettering Cancer Center
Co-authored papers 1
Memorial Sloan-Kettering Cancer Center
Co-authored papers 1
Harvard Medical School
Co-authored papers 1
Princeton University
Co-authored papers 1