Skip to Main Content

Author Details

Holger Fr??hlich
Bonn-Aachen International Center for IT (B-IT), University of Bonn
2004
119
29
Timothy Clark (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
36239995A Sequential Targeting Strategy Interrupts AKT-Driven Subclone-Mediated Progression in Glioblastoma.Clin Cancer Res2023
37681175MultiGML: Multimodal graph machine learning for prediction of adverse drug events.Heliyon2023
37347632A Transformer-Based Model Trained on Large Scale Claims Data for Prediction of Severe COVID-19 Disease Progression.IEEE J Biomed Health Inform2023
36780558AI reveals insights into link between CD33 and cognitive impairment in Alzheimer's Disease.PLoS Comput Biol2023
36801900Artificial intelligence-based clustering and characterization of Parkinson's disease trajectories.Sci Rep2023
36827273Bayesian network modeling of risk and prodromal markers of Parkinson's disease.PLoS One2023
34109729Unraveling the heterogeneity in Alzheimer's disease progression across multiple cohorts and the implications for data-driven disease modeling.Alzheimers Dement2022
35454993Epigenome-Wide Analysis of DNA Methylation in Parkinson's Disease Cortex.Life (Basel)2022
36452960Modeling approaches for early warning and monitoring of pandemic situations as well as decision support.Front Public Health2022
35986075Generation of realistic synthetic data using Multimodal Neural Ordinary Differential Equations.NPJ Digit Med2022
36380848Critical assessment of transformer-based AI models for German clinical notes.JAMIA Open2022
36124304Accurate prediction of virus-host protein-protein interactions via a Siamese neural network using deep protein sequence embeddings.Patterns (N Y)2022
35951526Ten quick tips for biomarker discovery and validation analyses using machine learning.PLoS Comput Biol2022
35279550Deep Learning-based detection of psychiatric attributes from German mental health records.Int J Med Inform2022
35266528GenRisk: a tool for comprehensive genetic risk modeling.Bioinformatics2022
35295840Leveraging the Potential of Digital Technology for Better Individualized Treatment of Parkinson's Disease.Front Neurol2022
32931565SEEDS: data driven inference of structural model errors and unknown inputs for dynamic systems biology.Bioinformatics2021
33734308Towards realizing the vision of precision medicine: AI based prediction of clinical drug response.Brain2021
33892789Remote monitoring technologies in Alzheimer's disease: design of the RADAR-AD study.Alzheimers Res Ther2021
34439949Comprehensive Profiling of Blood Coagulation and Fibrinolysis Marker Reveals Elevated Plasmin-Antiplasmin Complexes in Parkinson's Disease.Biology (Basel)2021
34514393CADA: phenotype-driven gene prioritization based on a case-enriched knowledge graph.NAR Genom Bioinform2021
34422142Caution, "normal" BMI: health risks associated with potentially masked individual underweight-EPMA Position Paper 2021.EPMA J2021
34040048A method for the rational selection of drug repurposing candidates from multimodal knowledge harmonization.Sci Rep2021
34095818An Explainable Multimodal Neural Network Architecture for Predicting Epilepsy Comorbidities Based on Administrative Claims Data.Front Artif Intell2021
32299344PathME: pathway based multi-modal sparse autoencoders for clustering of patient-level multi-omics data.BMC Bioinformatics2020
33693390Variational Autoencoder Modular Bayesian Networks for Simulation of Heterogeneous Clinical Study Data.Front Big Data2020
32028068Comprehensive analysis of tumor necrosis factor receptor TNFRSF9 (4-1BB) DNA methylation with regard to molecular and clinicopathological features, immune infiltrates, and response prediction to immunotherapy in melanoma.EBioMedicine2020
33344750Evaluating the Alzheimer's disease data landscape.Alzheimers Dement (N Y)2020
33154531Clustering of Alzheimer's and Parkinson's disease based on genetic burden of shared molecular mechanisms.Sci Rep2020
33091717Drug repositioning of antiretroviral ritonavir for combinatorial therapy in glioblastoma.Eur J Cancer2020
32620927Realistic simulation of virtual multi-scale, multi-modal patient trajectories using Bayesian networks and sparse auto-encoders.Sci Rep2020
32843907Differences in cohort study data affect external validation of artificial intelligence models for predictive diagnostics of dementia - lessons for translation into clinical practice.EPMA J2020
32839667Optimal multiparametric set-up modelled for best survival outcomes in palliative treatment of liver malignancies: unsupervised machine learning and 3 PM recommendations.EPMA J2020
32411185Corrigendum: The Impact of Pathway Database Choice on Statistical Enrichment Analysis and Predictive Modeling.Front Genet2020
30980104Benefits of a factorial design focusing on inclusion of female and male animals in one experiment.J Mol Med (Berl)2019
31730697Deep learning for clustering of multivariate clinical patient trajectories with missing values.Gigascience2019
31824580The Impact of Pathway Database Choice on Statistical Enrichment Analysis and Predictive Modeling.Front Genet2019
31296310Classic bladder exstrophy and adenocarcinoma of the bladder: Methylome analysis provide no evidence for underlying disease-mechanisms of this association.Cancer Genet2019
28902406Genetic and epigenetic insights into uveal melanoma.Clin Genet2018
30042519Using Multi-Scale Genetic, Neuroimaging and Clinical Data for Predicting Alzheimer's Disease and Reconstruction of Relevant Biological Mechanisms.Sci Rep2018
30145981From hype to reality: data science enabling personalized medicine.BMC Med2018
30199087Corrigendum.Clin Genet2018
29896316Premenopausal breast cancer: potential clinical utility of a multi-omics based machine learning approach for patient stratification.EPMA J2018
30352093Molecular signatures in IASLC/ATS/ERS classified growth patterns of lung adenocarcinoma.PLoS One2018
30563179Towards a Central Role of <i>ISL1</i> in the Bladder Exstrophy⁻Epispadias Complex (BEEC): Computational Characterization of Genetic Variants and Structural Modelling.Genes (Basel)2018
29518977Key Players of Cisplatin Resistance: Towards a Systems Pharmacology Approach.Int J Mol Sci2018
29467476A Simple 3-Parameter Model for Cancer Incidences.Sci Rep2018
28858780A Machine Learning Approach to Automated Gait Analysis for the Noldus Catwalk System.IEEE Trans Biomed Eng2018
28505258Modelling and mathematical analysis of the M$_{2}$ receptor-dependent joint signalling and secondary messenger network in CHO cells.Math Med Biol2018
27883297Patients' perception of Parkinson's disease-associated pain following initiation of rotigotine: a multicenter non-interventional study.Postgrad Med2017
  • 1 - 50 of 119

Recommended Authors

Anna Goldenberg
SickKids Research Institute
Career Start Year 2011
Number of shared co-authors 14
Joel T Dudley
Institute for Next Generation Healthcare
Career Start Year 2006
Number of shared co-authors 6
Woochang Hwang
College of Medicine, Hanyang University
Career Start Year 2006
Number of shared co-authors 1
Artem Sokolov
Harvard Medical School
Career Start Year 2006
Number of shared co-authors 7
Dongxiao Zhu
Wayne State University
Career Start Year 2005
Number of shared co-authors 0
Doheon Lee
Korea Advanced Institute of Science and Technology
Career Start Year 2004
Number of shared co-authors 0
Bin Zhang
Graduate School of Medicine, The University of Tokyo
Career Start Year 2004
Number of shared co-authors 10
Adam A Margolin
Icahn School of Medicine
Career Start Year 2004
Number of shared co-authors 15
Julio Saez-Rodriguez
Institute of Computational Biomedicine, Heidelberg University
Career Start Year 2004
Number of shared co-authors 22
Giuseppe Jurman
Data Science for Health Research Unit, Bruno Kessler Foundation
Career Start Year 2003
Number of shared co-authors 1
Andrei Zinovyev
INSERM U, Institut Curie, PSL Research University
Career Start Year 2003
Number of shared co-authors 3
Su-In Lee
University of Washington
Career Start Year 2003
Number of shared co-authors 2
Assaf Gottlieb
Center for Precision Health, University of Texas Health Science Center at Houston
Career Start Year 2002
Number of shared co-authors 0
J??rg Rahnenf??hrer
TU Dortmund University
Career Start Year 2002
Number of shared co-authors 3
Mar??a Rodr??guez Mart??nez
Herbert Irving Cancer Research Center, Columbia University Medical Center
Career Start Year 2002
Number of shared co-authors 3
Gil Alterovitz
Brigham and Women's Hospital
Career Start Year 2002
Number of shared co-authors 1
Frank Emmert-Streib
Tampere University
Career Start Year 2000
Number of shared co-authors 1
Tero Aittokallio
Institute for Molecular Medicine Finland (FIMM), University of Helsinki
Career Start Year 1999
Number of shared co-authors 13
Ranadip Pal
Texas Tech University
Career Start Year 1999
Number of shared co-authors 0
Igor Jurisica
Schroeder Arthritis Institute
Career Start Year 1998
Number of shared co-authors 4
Cesare Furlanello
Bruno Kessler Foundation
Career Start Year 1996
Number of shared co-authors 1
Samuel Kaski
Aalto University
Career Start Year 1995
Number of shared co-authors 11
Dimitris Anastassiou
Columbia University
Career Start Year 1995
Number of shared co-authors 0
Giorgio Valentini
Universita degli Studi di Milano
Career Start Year 1995
Number of shared co-authors 3
Pietro Li??
University of Cambridge
Career Start Year 1994
Number of shared co-authors 2
Jesper Tegn??r
King Abdullah University of Science and Technology (KAUST)
Career Start Year 1993
Number of shared co-authors 3
Andrea Califano
Columbia University
Career Start Year 1993
Number of shared co-authors 11
Fabian J Theis
Technical University of Munich
Career Start Year 1992
Number of shared co-authors 12
Bart De Moor
STADIUS Center for Dynamical Systems
Career Start Year 1990
Number of shared co-authors 1
Seiya Imoto
Human Genome Center, The Institute of Medical Science, The University of Tokyo
Career Start Year 1978
Number of shared co-authors 2

Collaborators

Martin Hofmann-Apitius
Co-authored papers 13
Holger S??ltmann
German Cancer Research Center (DKFZ)
Co-authored papers 8
Daniel Domingo-Fern??ndez
Fraunhofer Institute for Algorithms and Scientific Computing (SCAI)
Co-authored papers 7
Sumit Madan
Co-authored papers 6
Paurush Praveen
Miltenyi Biotec B.V. & Co. KG
Co-authored papers 5
Markus M N??then
Institute of Human Genetics, University Hospital Bonn
Co-authored papers 4
Per Hoffmann
Institute of Human Genetics, University of Bonn and University Hospital Bonn
Co-authored papers 4
Stefan Wiemann
Co-authored papers 3
Niko Beerenwinkel
ETH Zurich
Co-authored papers 3
Simon Lovestone
Janssen Medical Ltd
Co-authored papers 3
Enrico Glaab
University of Luxembourg
Co-authored papers 3
Stefan Herms
Institute of Human Genetics, University of Bonn
Co-authored papers 3
Andrea Hofmann
Institute of Human Genetics, University of Bonn and Department of Genomics
Co-authored papers 3
Hubert J M Smeets
Maastricht University Medical Centre+
Co-authored papers 2
Martin Glas
University Hospital Essen
Co-authored papers 2
Andreas Till
University Hospital Bonn
Co-authored papers 2
Charles Tapley Hoyt
Harvard Medical School
Co-authored papers 2
Anandhi Iyappan
Fraunhofer Institute for Algorithms and Scientific Computing (Fraunhofer SCAI)
Co-authored papers 2
Johannes Schumacher
Philipps University of Marburg
Co-authored papers 2
Juliane Fluck
Co-authored papers 2
Frank G Holz
University of Bonn
Co-authored papers 2
Bj??rn Scheffler
German Cancer Research Center (DKFZ)
Co-authored papers 2
Franziska Degenhardt
University of Duisburg-Essen
Co-authored papers 2
Stefanie Heilmann-Heimbach
Institute of Human Genetics, University Hospital of Bonn & University of Bonn
Co-authored papers 2
Susanne Moebus
Co-authored papers 2
Rainer Spang
University of Regensburg
Co-authored papers 2
Florian Markowetz
CRUK Cambridge Institute, University of Cambridge
Co-authored papers 2
Christian Ebeling
Co-authored papers 2
Wolfgang Wagner
Center for Integrated Oncology Aachen Bonn Cologne Dusseldorf (CIO ABCD)
Co-authored papers 2
Genevera I Allen
Jan and Dan Duncan Neurological Research Institute at Texas Children's Hospital
Co-authored papers 1
Release 1.2