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Author Details

Gideon M Hirschfield
University of Toronto
2001
313
68
PMIDPaper TitleJournal TitlePublished Year
37399238Adequate versus deep response to ursodeoxycholic acid in primary biliary cholangitis: To what extent and under what conditions is normal alkaline phosphatase level associated with complication-free survival gain?Hepatology2024
37904314Open-label, clinical trial extension: Two-year safety and efficacy results of seladelpar in patients with primary biliary cholangitis.Aliment Pharmacol Ther2024
37945164Primary Biliary Cholangitis: Pathophysiology.Clin Liver Dis2024
36343847GLIMMER: A Randomized Phase 2b Dose-Ranging Trial of Linerixibat in Primary Biliary Cholangitis Patients With Pruritus.Clin Gastroenterol Hepatol2023
37534935Living donor liver transplantation can address disparities in transplant access for patients with primary sclerosing cholangitis.Hepatol Commun2023
37191344Bacterial and metabolic phenotypes associated with inadequate response to ursodeoxycholic acid treatment in primary biliary cholangitis.Gut Microbes2023
37157905Optimizing therapy in primary biliary cholangitis: Alkaline phosphatase at six months identifies one-year non-responders and predicts survival.Liver Int2023
37386786Seladelpar efficacy and safety at 3 months in patients with primary biliary cholangitis: ENHANCE, a phase 3, randomized, placebo-controlled study.Hepatology2023
37184523Safety, tolerability, and efficacy of maralixibat in adults with primary sclerosing cholangitis: Open-label pilot study.Hepatol Commun2023
36964518Improving quality of life in patients with rare autoimmune liver diseases by structured peer-delivered support (Q.RARE.LI): study protocol for a transnational effectiveness-implementation hybrid trial.BMC Psychiatry2023
37026715Regulation of immune responses in primary biliary cholangitis: a transcriptomic analysis of peripheral immune cells.Hepatol Commun2023
36621963Ursodeoxycholic Acid Treatment-Induced GLOBE Score Changes Are Associated With Liver Transplantation-Free Survival in Patients With Primary Biliary Cholangitis.Am J Gastroenterol2023
36809835New Treatment Paradigms in Primary Biliary Cholangitis.Clin Gastroenterol Hepatol2023
36468575Geographical region and clinical outcomes of patients with primary biliary cholangitis from Western Europe.Eur J Gastroenterol Hepatol2023
36870613Primary sclerosing cholangitis and overlap features of autoimmune hepatitis: A coming of age or an age-ist problem?J Hepatol2023
36639314Corrigendum to: "An international genome-wide meta-analysis of primary biliary cholangitis: Novel risk loci and candidate drugs" [J Hepatol 75 (2021) 572-581].J Hepatol2023
35961518UK-Wide Multicenter Evaluation of Second-line Therapies in Primary Biliary Cholangitis.Clin Gastroenterol Hepatol2023
34231037Evaluation of quantitative MRCP (MRCP+) for risk stratification of primary sclerosing cholangitis: comparison with morphological MRCP, MR elastography, and biochemical risk scores.Eur Radiol2022
35609437The relationship between disease activity and UDCA response criteria in primary biliary cholangitis: A cohort study.EBioMedicine2022
35397207Progressive liver, kidney, and heart degeneration in children and adults affected by TULP3 mutations.Am J Hum Genet2022
35367282A phase II, randomized, open-label, 52-week study of seladelpar in patients with primary biliary cholangitis.J Hepatol2022
35777587Liver stiffness measurement by vibration-controlled transient elastography improves outcome prediction in primary biliary cholangitis.J Hepatol2022
36150526Greater Transplant-Free Survival in Patients Receiving Obeticholic Acid for Primary Biliary Cholangitis in a Clinical Trial Setting Compared to Real-World External Controls.Gastroenterology2022
36138566Liver transplant-free survival according to alkaline phosphatase and GLOBE score in patients with primary biliary cholangitis treated with ursodeoxycholic acid.Aliment Pharmacol Ther2022
36270719Autoantibodies in Primary Biliary Cholangitis.Clin Liver Dis2022
36267872Farnesoid X receptor agonist tropifexor attenuates cholestasis in a randomised trial in patients with primary biliary cholangitis.JHEP Rep2022
36327436A Randomized, Dose-Finding, Proof-of-Concept Study of Berberine Ursodeoxycholate in Patients With Primary Sclerosing Cholangitis.Am J Gastroenterol2022
36223935Trends in liver transplantation for autoimmune liver diseases: a Canadian study.Can J Surg2022
35977610Reply to: "Seladelpar in patients with primary biliary cholangitis: Need for a closer look!"J Hepatol2022
34951722Machine learning in primary biliary cholangitis: A novel approach for risk stratification.Liver Int2022
35220609Ethnicity, disease severity, and survival in Canadian patients with primary biliary cholangitis.Hepatology2022
35143897Risk factors and outcomes associated with recurrent autoimmune hepatitis following liver transplantation.J Hepatol2022
35133427Elevated Serum Aminotransferases.JAMA2022
34403559Seladelpar improved measures of pruritus, sleep, and fatigue and decreased serum bile acids in patients with primary biliary cholangitis.Liver Int2022
34548339The human liver microenvironment shapes the homing and function of CD4<sup>+</sup> T-cell populations.Gut2022
34626833Clinical Utility of Magnetic Resonance Imaging Biomarkers for Identifying Nonalcoholic Steatohepatitis Patients at High Risk of Progression: A Multicenter Pooled Data and Meta-Analysis.Clin Gastroenterol Hepatol2022
32562892Effects of Primary Biliary Cholangitis on Quality of Life and Health Care Costs in the United Kingdom.Clin Gastroenterol Hepatol2021
35989897Single Topic Conference on Autoimmune Liver Disease from the Canadian Association for the Study of the Liver.Can Liver J2021
33493696The Epidemiology of UK Autoimmune Liver Disease Varies With Geographic Latitude.Clin Gastroenterol Hepatol2021
33488578CD80 on Human T Cells Is Associated With FoxP3 Expression and Supports Treg Homeostasis.Front Immunol2021
33484775A randomized placebo-controlled trial of elafibranor in patients with primary biliary cholangitis and incomplete response to UDCA.J Hepatol2021
33872692Downregulation of TGR5 (GPBAR1) in biliary epithelial cells contributes to the pathogenesis of sclerosing cholangitis.J Hepatol2021
33898959Potent suppression of hydrophobic bile acids by aldafermin, an FGF19 analogue, across metabolic and cholestatic liver diseases.JHEP Rep2021
33584535Correlations Between MRI Biomarkers PDFF and cT1 With Histopathological Features of Non-Alcoholic Steatohepatitis.Front Endocrinol (Lausanne)2021
34406347Sex Disparity in Liver Transplant and Access to Living Donation.JAMA Surg2021
34425003Editorial: liver disease in secondary care-'money or your life'. Authors' reply.Aliment Pharmacol Ther2021
33942335Letter to the Editor: Are We Confident That Primary Biliary Cholangitis Liver-Related Mortality Is Higher in Males?Hepatology2021
33941746A Comparison of Prognostic Scores (Mayo, UK-PBC, and GLOBE) in Primary Biliary Cholangitis.Am J Gastroenterol2021
34129689The Serum Proteome and Ursodeoxycholic Acid Response in Primary Biliary Cholangitis.Hepatology2021
34181776Internal medicine hospitalisations and liver disease: a comparative disease burden analysis of a multicentre cohort.Aliment Pharmacol Ther2021
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Collaborators

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University of Toronto, Lunenfeld Tanenbaum Research Institute, Mount Sinai Hospital
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Co-authored papers 17
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Co-authored papers 17
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University of Cambridge
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Baylor College of Medicine
Co-authored papers 12
Chaohu Hospital Affiliated to Anhui Medical University
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Pinnacle Clinical Research Center
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Mayo Clinic
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University of California davis
Co-authored papers 6
Institute of Clinical Molecular Biology, Kiel University
Co-authored papers 5
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Wellcome Sanger Institute
Co-authored papers 5
Population Health Sciences Institute, Newcastle University
Co-authored papers 5
US Department of Veterans Affairs Medical Center
Co-authored papers 5
Scripps Clinic and Scripps Translational Science Institute
Co-authored papers 5
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Mayo Clinic
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Institute for Clinical and Translational Research, Baylor College of Medicine
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Institute of Biomedical Technologies, National Research Council of Italy
Co-authored papers 3
Queen Elizabeth Hospital Birmingham
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Virginia Commonwealth University
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