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Author Details

Gregory W Carter
Tufts University School of Medicine
2005
61
20
PMIDPaper TitleJournal TitlePublished Year
36906075Reduction in GABAB on glia induce Alzheimer's disease related changes.Brain Behav Immun2023
37614242Bridging the rodent to human translational gap: Marmosets as model systems for the study of Alzheimer's disease.Alzheimers Dement (N Y)2023
37547005Characterization of covalent inhibitors that disrupt the interaction between the tandem SH2 domains of SYK and FCER1G phospho-ITAM.bioRxiv2023
37217254Variation in histone configurations correlates with gene expression across nine inbred strains of mice.Genome Res2023
37215505Open drug discovery in Alzheimer's disease.Alzheimers Dement (N Y)2023
37016304Differential splicing of neuronal genes in a Trem2*R47H mouse model mimics alterations associated with Alzheimer's disease.BMC Genomics2023
373652403D bioengineered neural tissue generated from patient-derived iPSCs mimics time-dependent phenotypes and transcriptional features of Alzheimer's disease.Mol Psychiatry2023
37162857Transcriptome Analysis Reveals Organ-Specific Effects of 2-Deoxyglucose Treatment in Healthy Mice.bioRxiv2023
36641439A novel human tau knock-in mouse model reveals interaction of Abeta and human tau under progressing cerebral amyloidosis in 5xFAD mice.Alzheimers Res Ther2023
35197847Corrigendum: Uncovering Disease Mechanisms in a Novel Mouse Model Expressing Humanized APOEε4 and Trem2<sup>*</sup>R47H.Front Aging Neurosci2022
35846156Prophylactic evaluation of verubecestat on disease- and symptom-modifying effects in 5XFAD mice.Alzheimers Dement (N Y)2022
35675330Identification of Arhgef12 and Prkci as genetic modifiers of retinal dysplasia in the Crb1rd8 mouse model.PLoS Genet2022
35370604The <i>APOE</i> <sup>ε3/ε4</sup> Genotype Drives Distinct Gene Signatures in the Cortex of Young Mice.Front Aging Neurosci2022
35813947<i>Plcg2<sup>M28L</sup></i> Interacts With High Fat/High Sugar Diet to Accelerate Alzheimer's Disease-Relevant Phenotypes in Mice.Front Aging Neurosci2022
35448524Independent and Interactive Effects of Genetic Background and Sex on Tissue Metabolomes of Adipose, Skeletal Muscle, and Liver in Mice.Metabolites2022
36142331Single-Cell RNA Sequencing Reveals Molecular Features of Heterogeneity in the Murine Retinal Pigment Epithelium.Int J Mol Sci2022
36016830Pharmacokinetic, pharmacodynamic, and transcriptomic analysis of chronic levetiracetam treatment in 5XFAD mice: A MODEL-AD preclinical testing core study.Alzheimers Dement (N Y)2022
34366832Comprehensive Evaluation of the 5XFAD Mouse Model for Preclinical Testing Applications: A MODEL-AD Study.Front Aging Neurosci2021
33567283Natural genetic variation determines microglia heterogeneity in wild-derived mouse models of Alzheimer's disease.Cell Rep2021
33733350The Combined Analysis of Pleiotropy and Epistasis (CAPE).Methods Mol Biol2021
33892506Effects of kinship correction on inflation of genetic interaction statistics in commonly used mouse populations.G3 (Bethesda)2021
34707490Uncovering Disease Mechanisms in a Novel Mouse Model Expressing Humanized APOEε4 and Trem2*R47H.Front Aging Neurosci2021
32492070Transcriptomic stratification of late-onset Alzheimer's cases reveals novel genetic modifiers of disease pathology.PLoS Genet2020
32001511HELLS and PRDM9 form a pioneer complex to open chromatin at meiotic recombination hot spots.Genes Dev2020
31929156Staging Alzheimer's Disease in the Brain and Retina of B6.APP/PS1 Mice by Transcriptional Profiling.J Alzheimers Dis2020
31694854Genetic Interactions Affect Lung Function in Patients with Systemic Sclerosis.G3 (Bethesda)2020
33172468A novel systems biology approach to evaluate mouse models of late-onset Alzheimer's disease.Mol Neurodegener2020
33283040Model organism development and evaluation for late-onset Alzheimer's disease: MODEL-AD.Alzheimers Dement (N Y)2020
33188183Molecular estimation of neurodegeneration pseudotime in older brains.Nat Commun2020
33273466Author Correction: Molecular estimation of neurodegeneration pseudotime in older brains.Nat Commun2020
32668255Meta-Analysis of the Alzheimer's Disease Human Brain Transcriptome and Functional Dissection in Mouse Models.Cell Rep2020
30593494Tissue-Specific Trans Regulation of the Mouse Epigenome.Genetics2019
31878951Genetic perturbations of disease risk genes in mice capture transcriptomic signatures of late-onset Alzheimer's disease.Mol Neurodegener2019
31510680Identifying and ranking potential driver genes of Alzheimer's disease using multiview evidence aggregation.Bioinformatics2019
31150388Enhancing face validity of mouse models of Alzheimer's disease with natural genetic variation.PLoS Genet2019
30649999Uncoupling of transcriptomic and cytological differentiation in mouse spermatocytes with impaired meiosis.Mol Biol Cell2019
29507048A Bayesian Framework for Generalized Linear Mixed Modeling Identifies New Candidate Loci for Late-Onset Alzheimer's Disease.Genetics2018
30017478The Tandem Duplicator Phenotype Is a Prevalent Genome-Wide Cancer Configuration Driven by Distinct Gene Mutations.Cancer Cell2018
28592500Epistatic Networks Jointly Influence Phenotypes Related to Metabolic Disease and Gene Expression in Diversity Outbred Mice.Genetics2017
28459858Epistatic interaction between the lipase-encoding genes Pnpla2 and Lipe causes liposarcoma in mice.PLoS Genet2017
28358130Genetic interactions improve models of quantitative traits.Nat Genet2017
28978474Precocious Interleukin 21 Expression in Naive Mice Identifies a Natural Helper Cell Population in Autoimmune Disease.Cell Rep2017
26828925Weak Epistasis Generally Stabilizes Phenotypes in a Mouse Intercross.PLoS Genet2016
27519264Regulatory complexity revealed by integrated cytological and RNA-seq analyses of meiotic substages in mouse spermatocytes.BMC Genomics2016
26351520Affinity-seq detects genome-wide PRDM9 binding sites and reveals the impact of prior chromatin modifications on mammalian recombination hotspot usage.Epigenetics Chromatin2015
24297548Dissection of complex gene expression using the combined analysis of pleiotropy and epistasis.Pac Symp Biocomput2014
25251056A genetic interaction network model of a complex neurological disease.Genes Brain Behav2014
23550134Inferring gene function and network organization in Drosophila signaling by combined analysis of pleiotropy and epistasis.G3 (Bethesda)2013
24274089Clustering of transcriptional profiles identifies changes to insulin signaling as an early event in a mouse model of Alzheimer's disease.BMC Genomics2013
24204223CAPE: an R package for combined analysis of pleiotropy and epistasis.PLoS Comput Biol2013
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Collaborators

Gareth R Howell
Tufts University Graduate School of Biomedical Sciences
Co-authored papers 16
Lara M Mangravite
Children's Hospital Oakland Research Institute
Co-authored papers 10
Christoph Preuss
Universite de Montreal
Co-authored papers 10
Benjamin A Logsdon
Fred Hutchinson Cancer Research Center
Co-authored papers 10
Timothy Galitski
Institute for Systems Biology
Co-authored papers 8
Vivek M Philip
Center for Computational Sciences
Co-authored papers 6
Sumit Mukherjee
Microsoft Corporation
Co-authored papers 4
Philip L De Jager
Columbia University Medical Center
Co-authored papers 4
Solveig K Sieberts
University of Washington
Co-authored papers 4
Anna K Greenwood
Fred Hutchinson Cancer Research Center
Co-authored papers 4
David A Bennett
Rush University Medical Center
Co-authored papers 3
John M Mahoney
Larner College of Medicine, University of Vermont
Co-authored papers 3
Gary A Churchill
Tufts University
Co-authored papers 3
Robyn L Ball
Stanford University
Co-authored papers 3
Thanneer M Perumal
F. Hoffmann-La Roche Ltd
Co-authored papers 3
Nil??fer Ertekin-Taner
Mayo Clinic
Co-authored papers 3
Nathan D Price
Institute for Systems Biology
Co-authored papers 2
Larsson Omberg
Cornell University
Co-authored papers 2
Catherine C Kaczorowski
The University of Michigan ann arbor
Co-authored papers 2
Baha El Kassaby
Diamond Light Source Ltd, Harwell Science and Innovation Campus
Co-authored papers 2
Suman Jayadev
University of Washington
Co-authored papers 2
Gwenn A Garden
University of Washington School of Medicine
Co-authored papers 2
Natalie R Powers
Yale University School of Medicine
Co-authored papers 2
Ilya Shmulevich
Institute for Systems Biology
Co-authored papers 2
Vesteinn Thorsson
Institute for Systems Biology
Co-authored papers 2
Matthew A Hibbs
Co-authored papers 2
Opher Gileadi
Structural Genomics Consortium Karolinska Institute Stockholm Sweden.
Co-authored papers 2
Allan I Levey
Emory University School of Medicine
Co-authored papers 2
Jungwoo Wren Kim
Institute for Cell Engineering, Johns Hopkins University School of Medicine
Co-authored papers 1
David J Dilworth
Institute for Systems Biology
Co-authored papers 1
Release 1.2