Author details

Full Name

Kunio Nagashima

Affiliation

ORCID

Career Start Year

1976

Papers

193

H Index

Expertise

CM4AI Collaborator

PMID	Paper Title	Journal Title	Published Year
36975211	Reserpine maintains photoreceptor survival in retinal ciliopathy by resolving proteostasis imbalance and ciliogenesis defects.	Elife	2023
37279797	A Single-Arm, Open-Label Phase II Study of ONC201 in Recurrent/Refractory Metastatic Breast Cancer and Advanced Endometrial Carcinoma.	Oncologist	2023
34787650	CEP97 phosphorylation by Dyrk1a is critical for centriole separation during multiciliogenesis.	J Cell Biol	2022
36170207	Delivery of ceramide phosphoethanolamine lipids to the cleavage furrow through the endocytic pathway is essential for male meiotic cytokinesis.	PLoS Biol	2022
34521765	Adenosine A2A Receptor Activation Enhances Blood-Tumor Barrier Permeability in a Rodent Glioma Model.	Mol Cancer Res	2021
34290273	Interleukin-27 promotes autophagy in human serum-induced primary macrophages via an mTOR- and LC3-independent pathway.	Scientific Reports	2021
33662400	SSSPTA is essential for serine palmitoyltransferase function during development and hematopoiesis.	Journal of Biological Chemistry	2021
33918371	FIB-SEM as a Volume Electron Microscopy Approach to Study Cellular Architectures in SARS-CoV-2 and Other Viral Infections: A Practical Primer for a Virologist.	Viruses	2021
33649225	HIV-1 cores retain their integrity until minutes before uncoating in the nucleus.	Proceedings of the National Academy of Sciences of the United States of America	2021
33323015	Autophosphorylation-induced self-assembly and STIL-dependent reinforcement underlie Plk4's ring-to-dot localization conversion around a human centriole.	Cell Cycle	2020
32049013	A FLCN-TFE3 Feedback Loop Prevents Excessive Glycogenesis and Phagocyte Activation by Regulating Lysosome Activity.	Cell Rep	2020
32094182	HIV-1 uncoats in the nucleus near sites of integration.	Proceedings of the National Academy of Sciences of the United States of America	2020
33016243	Naturally Acquired Mouse Kidney Parvovirus Infection Produces a Persistent Interstitial Nephritis in Immunocompetent Laboratory Mice.	Veterinary Pathology	2020
31357166	A PLPPV sequence in the p8 region of Gag provides late domain function for mouse mammary tumor virus.	Virology	2019
31631019	Improved Retinal Organoid Differentiation by Modulating Signaling Pathways Revealed by Comparative Transcriptome Analyses with Development InÂ Vivo.	Stem Cell Reports	2019
31270137	Developmentally regulated GTP-binding protein 1 modulates ciliogenesis via an interaction with Dishevelled.	Journal of Cell Biology	2019
29769289	Metarrestin, a perinucleolar compartment inhibitor, effectively suppresses metastasis.	Sci Transl Med	2018
29039094	Immunoelectron Microscopy for Visualization of Nanoparticles.	Methods in Molecular Biology	2018
30185559	Defective cortex glia plasma membrane structure underlies light-induced epilepsy in mutants.	Proceedings of the National Academy of Sciences of the United States of America	2018
29719618	ONC201 kills breast cancer cells <i>in vitro</i> by targeting mitochondria.	Oncotarget	2018
28125936	An Adult Mouse Thyroid Side Population Cell Line that Exhibits Enriched Epithelial-Mesenchymal Transition.	Thyroid	2017
28446240	Molecular mechanisms by which HERV-K Gag interferes with HIV-1 Gag assembly and particle infectivity.	Retrovirology	2017
28369466	REEP6 mediates trafficking of a subset of Clathrin-coated vesicles and is critical for rod photoreceptor function and survival.	Hum Mol Genet	2017
28700940	InÂ Vitro Modeling Using Ciliopathy-Patient-Derived Cells Reveals Distinct Cilia Dysfunctions Caused by CEP290 Mutations.	Cell Rep	2017
27003604	Polyclonal Crypt Genesis and Development of Familial Small Intestinal Neuroendocrine Tumors.	Gastroenterology	2016
26962944	HIV-1 Nucleocapsid Mimics the Membrane Adaptor Syntenin PDZ to Gain Access to ESCRTs and Promote Virus Budding.		2016
26421679	Ty3 Retrotransposon Hijacks Mating Yeast RNA Processing Bodies to Infect New Genomes.	PLoS Genet	2015
25775561	Folliculin-interacting proteins Fnip1 and Fnip2 play critical roles in kidney tumor suppression in cooperation with Flcn.	Proc Natl Acad Sci U S A	2015
25609380	Chromatin decompaction by the nucleosomal binding protein HMGN5 impairs nuclear sturdiness.	Nature Communications	2015
26002800	Activated platelet-T-cell conjugates in peripheral blood of patients with HIV infection: coupling coagulation/inflammation and T cells.	AIDS	2015
24642596	Ceramide transfer protein deficiency compromises organelle function and leads to senescence in primary cells.	PLoS ONE	2014
24908670	Folliculin (Flcn) inactivation leads to murine cardiac hypertrophy through mTORC1 deregulation.	Human Molecular Genetics	2014
24947469	Ciliopathy-associated gene Cc2d2a promotes assembly of subdistal appendages on the mother centriole during cilia biogenesis.	Nat Commun	2014
25002678	Phosphatidic acid phospholipase A1 mediates ER-Golgi transit of a family of G protein-coupled receptors.	Journal of Cell Biology	2014
23408603	Roles played by capsid-dependent induction of membrane curvature and Gag-ESCRT interactions in tetherin recruitment to HIV-1 assembly sites.	Journal of Virology	2013
23895345	Ubiquitin conjugation to Gag is essential for ESCRT-mediated HIV-1 budding.	Retrovirology	2013
24290756	An IKKÎ±-nucleophosmin axis utilizes inflammatory signaling to promote genome integrity.	Cell Rep	2013
23684610	Essential regulation of lung surfactant homeostasis by the orphan G protein-coupled receptor GPR116.	Cell Reports	2013
23099087	Elements in HIV-1 Gag contributing to virus particle assembly.	Virus Research	2013
23671100	Murine leukemia virus glycosylated Gag blocks apolipoprotein B editing complex 3 and cytosolic sensor access to the reverse transcription complex.	Proceedings of the National Academy of Sciences of the United States of America	2013
23555259	Dimeric RNA recognition regulates HIV-1 genome packaging.	PLoS Pathogens	2013
23343771	Essential role of Cenexin1, but not Odf2, in ciliogenesis.	Cell Cycle	2013
22248819	DNA immunization with HBsAg-based particles expressing a B cell epitope of amyloid Î²-peptide attenuates disease progression and prolongs survival in a mouse model of Alzheimer's disease.	Vaccine	2012
22345468	Budding of retroviruses utilizing divergent L domains requires nucleocapsid.	Journal of Virology	2012
22870217	Identification of CBX3 and ABCA5 as putative biomarkers for tumor stem cells in osteosarcoma.	PLoS One	2012
22454152	Thyroid regeneration: characterization of clear cells after partial thyroidectomy.	Endocrinology	2012
22993163	Functional redundancy in HIV-1 viral particle assembly.	Journal of Virology	2012
22984402	Melanoregulin, product of the dsu locus, links the BLOC-pathway and OA1 in organelle biogenesis.	PLoS ONE	2012
23150719	Regulation of mitochondrial oxidative metabolism by tumor suppressor FLCN.	Journal of the National Cancer Institute	2012
23144615	Structural and functional insights into the HIV-1 maturation inhibitor binding pocket.	PLoS Pathogens	2012