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Author Details

Ningyan Zhang
Stem Cell Translational Research Center of Tongji Hospital, Tongji University
2000
102
33
PMIDPaper TitleJournal TitlePublished Year
37935033Leptin Reduction as a Required Component for Weight Loss.Diabetes2024
36411391A potent and broad neutralization of SARS-CoV-2 variants of concern by DARPins.Nat Chem Biol2023
38078382An ACE2 decamer viral trap as a durable intervention solution for current and future SARS-CoV.Emerg Microbes Infect2023
37992151Hyperleptinemia contributes to antipsychotic drug-associated obesity and metabolic disorders.Sci Transl Med2023
37816743Vaccination with a replication-defective cytomegalovirus vaccine elicits a glycoprotein B-specific monoclonal antibody repertoire distinct from natural infection.NPJ Vaccines2023
37100807Overcoming adaptive resistance to anti-VEGF therapy by targeting CD5L.Nat Commun2023
37328286A highly selective humanized DDR1 mAb reverses immune exclusion by disrupting collagen fiber alignment in breast cancer.J Immunother Cancer2023
36696925Endotrophin neutralization through targeted antibody treatment protects from renal fibrosis in a podocyte ablation model.Mol Metab2023
36762937Antibody therapies for the treatment of acute myeloid leukemia: exploring current and emerging therapeutic targets.Expert Opin Investig Drugs2023
35338087Development of a TCR-like antibody and chimeric antigen receptor against NY-ESO-1/HLA-A2 for cancer immunotherapy.J Immunother Cancer2022
35793453An Enzymatically Cleavable Tripeptide Linker for Maximizing the Therapeutic Index of Antibody-Drug Conjugates.Mol Cancer Ther2022
35425350Homogeneous antibody-angiopep 2 conjugates for effective brain targeting.RSC Adv2022
35717259LILRB2-mediated TREM2 signaling inhibition suppresses microglia functions.Mol Neurodegener2022
35388745Enhanced anti-angiogenetic effect of transferrin receptor-mediated delivery of VEGF-trap in a glioblastoma mouse model.MAbs2022
36540309Engineering antibody and protein therapeutics to cross the blood-brain barrier.Antib Ther2022
36683763A novel humanized Chi3l1 blocking antibody attenuates acetaminophen-induced liver injury in mice.Antib Ther2022
36525420Anti-GRP-R monoclonal antibody antitumor therapy against neuroblastoma.PLoS One2022
35941707Human adipose-derived mesenchymal stem cells-derived exosomes encapsulated in pluronic F127 hydrogel promote wound healing and regeneration.Stem Cell Res Ther2022
36211388Blocking LAIR1 signaling in immune cells inhibits tumor development.Front Immunol2022
36104515Impairment of IgG Fc functions promotes tumor progression and suppresses NK cell antitumor actions.Commun Biol2022
36070367A tetravalent TREM2 agonistic antibody reduced amyloid pathology in a mouse model of Alzheimer's disease.Sci Transl Med2022
36138032Engineering SARS-CoV-2 specific cocktail antibodies into a bispecific format improves neutralizing potency and breadth.Nat Commun2022
36302510Antibody therapeutics for epithelial ovarian cancer.Expert Opin Biol Ther2022
35921534Discovery and engineering of an anti-TREM2 antibody to promote amyloid plaque clearance by microglia in 5XFAD mice.MAbs2022
35132410Engineering SARS-CoV-2 cocktail antibodies into a bispecific format improves neutralizing potency and breadth.bioRxiv2022
34952264Recent progress in development of monoclonal antibodies against human cytomegalovirus.Curr Opin Virol2022
35275718Structural basis for HCMV Pentamer recognition by neuropilin 2 and neutralizing antibodies.Sci Adv2022
32918786Leukocyte immunoglobulin-like receptor B1 and B4 (LILRB1 and LILRB4): Highly sensitive and specific markers of acute myeloid leukemia with monocytic differentiation.Cytometry B Clin Cytom2021
33795676Presence of complete murine viral genome sequences in patient-derived xenografts.Nat Commun2021
33682795Inhibition of astrocyte hemichannel improves recovery from spinal cord injury.JCI Insight2021
33904407Asprosin-neutralizing antibodies as a treatment for metabolic syndrome.Elife2021
33482584Chemical generation of small molecule-based bispecific antibody-drug conjugates for broadening the target scope.Bioorg Med Chem2021
33928233Leukocyte immunoglobulin-like receptor subfamily B: therapeutic targets in cancer.Antib Ther2021
33917421Human Endogenous Retroviruses in Glioblastoma Multiforme.Microorganisms2021
33556256Serum levels of endotrophin are associated with nonalcoholic steatohepatitis.Scand J Gastroenterol2021
35122056LILRB3 supports acute myeloid leukemia development and regulates T-cell antitumor immune responses through the TRAF2-cFLIP-NF-κB signaling axis.Nat Cancer2021
34380633Oncostatin M Receptor-Targeted Antibodies Suppress STAT3 Signaling and Inhibit Ovarian Cancer Growth.Cancer Res2021
34732895Tumour DDR1 promotes collagen fibre alignment to instigate immune exclusion.Nature2021
34078915A conditionally replication-defective cytomegalovirus vaccine elicits potent and diverse functional monoclonal antibodies in a phase I clinical trial.NPJ Vaccines2021
34210985Author Correction: Molecular determinants and mechanism for antibody cocktail preventing SARS-CoV-2 escape.Nat Commun2021
34112795Antibody-drug conjugates with dual payloads for combating breast tumor heterogeneity and drug resistance.Nat Commun2021
34110284Chitinase 3-like-1 contributes to acetaminophen-induced liver injury by promoting hepatic platelet recruitment.Elife2021
34082438Nasal delivery of an IgM offers broad protection from SARS-CoV-2 variants.Nature2021
33361306Potent Bispecific Neutralizing Antibody Targeting Glycoprotein B and the gH/gL/pUL128/130/131 Complex of Human Cytomegalovirus.Antimicrob Agents Chemother2021
33473140Molecular determinants and mechanism for antibody cocktail preventing SARS-CoV-2 escape.Nat Commun2021
32879051LILRB4-targeting Antibody-Drug Conjugates for the Treatment of Acute Myeloid Leukemia.Mol Cancer Ther2020
31988105Critical Role of Matrix Metalloproteinase 14 in Adipose Tissue Remodeling during Obesity.Mol Cell Biol2020
33151102A monoclonal antibody with broad specificity for the ligands of insulin B:9-23 reactive T cells prevents spontaneous type 1 diabetes in mice.MAbs2020
32745149Recognition of a highly conserved glycoprotein B epitope by a bivalent antibody neutralizing HCMV at a post-attachment step.PLoS Pathog2020
32771992Antagonistic anti-LILRB1 monoclonal antibody regulates antitumor functions of natural killer cells.J Immunother Cancer2020
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Collaborators

Zhiqiang An
Zhengzhou University
Co-authored papers 91
Hang Su
Co-authored papers 9
Byung-Kwon Choi
Baylor College of Medicine
Co-authored papers 7
Amy S Espeseth
Merck & Co., Inc.
Co-authored papers 6
Zihao Yuan
Auburn University
Co-authored papers 6
Jason S McLellan
Co-authored papers 6
Chisato Yamasaki
Osaka University
Co-authored papers 5
Pei-Yong Shi
University of Texas Medical Branch
Co-authored papers 5
Xuping Xie
University of Texas Medical Branch
Co-authored papers 5
Vineet D Menachery
University of Texas Medical Branch
Co-authored papers 5
Anil K Sood
The University of Texas MD Anderson Cancer Center
Co-authored papers 4
Naoto T Ueno
Cancer Research Center of Hawaii: University of Hawai'i Cancer Center.
Co-authored papers 3
Kalpit A Vora
Co-authored papers 3
Yize Li
Co-authored papers 2
Michael J Birrer
Co-authored papers 2
Cristina Ivan
The University of Texas MD Anderson Cancer Center
Co-authored papers 2
Hongjie Xia
University of Texas Medical Branch
Co-authored papers 2
Robert H Collins
University of Texas Southwestern Medical Center
Co-authored papers 2
Wenjin Jim Zheng
University of Texas Health Science Center at Houston
Co-authored papers 2
Michael S Diamond
Washington University School of Medicine
Co-authored papers 1
Hui Zheng
Baylor College of Medicine
Co-authored papers 1
Takae Kiyama
University of Texas Health Science Center at Houston Medical School
Co-authored papers 1
Kimberly Stegmaier
Dana-Farber Cancer Institute
Co-authored papers 1
Giovanni Roti
University of Parma
Co-authored papers 1
Claudine Isaacs
Co-authored papers 1
Yuntao Yang
University of Texas Health Science Center at Houston
Co-authored papers 1
Young Do Kwon
Co-authored papers 1
Daizhan Zhou
The Fourth Affiliated Hospital, Zhejiang University School of Medicine
Co-authored papers 1
Wenjin Zheng
University of Texas Health Science Center at Houston
Co-authored papers 1
Deborah L Berry
Lombardi Comprehensive Cancer Center, Georgetown University
Co-authored papers 1
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