Author details

Full Name

Christopher J Gibson

Affiliation

ORCID

Career Start Year

2008

Papers

H Index

Expertise

CM4AI Collaborator

PMID	Paper Title	Journal Title	Published Year
37483562	Prediction of risk for myeloid malignancy in clonal hematopoiesis.	NEJM Evid	2023
36163163	'ADVANCE' (a pilot trial) ADjuVANt chemotherapy in the elderly: Developing and evaluating lower-toxicity chemotherapy options for older patients with breast cancer.	Journal of Geriatric Oncology	2023
35443568	Molecular assessment and the current limits of post-transplant prognostication for chronic myelomonocytic leukemia.	Haematologica	2023
37595362	PPM1D modulates hematopoietic cell fitness and response to DNA damage and is a therapeutic target in myeloid malignancy.	Blood	2023
37909388	Somatic TET2 Mutations are Associated with Giant Cell Arteritis.		2023
36652671	A practical approach to curate clonal hematopoiesis of indeterminate potential in human genetic data sets.	Blood	2023
36949957	<i>TP53-</i>mediated clonal hematopoiesis confers increased risk for incident atherosclerotic disease.	Nat Cardiovasc Res	2023
37115512	Clonal Hematopoiesis in Young Women Treated for Breast Cancer.		2023
37042724	Clonal hematopoiesis in older patients with breast cancer receiving chemotherapy.		2023
37498674	Genetic modification of inflammation- and clonal hematopoiesis-associated cardiovascular risk.	J Clin Invest	2023
35286378	Impact of diagnostic genetics on remission MRD and transplantation outcomes in older patients with AML.	Blood	2022
35773251	Allosteric inhibition of PPM1D serine/threonine phosphatase via an altered conformational state.	Nat Commun	2022
35714308	TET2-mutant clonal hematopoiesis and risk of gout.	Blood	2022
35584376	Allelic complexity of KMT2A partial tandem duplications in acute myeloid leukemia and myelodysplastic syndromes.	Blood advances	2022
36096050	Clonal hematopoiesis of indeterminate potential andÂ risk of death from COVID-19.	Blood	2022
35385311	Mendelian randomization supports bidirectional causality between telomere length and clonal hematopoiesis of indeterminate potential.	Sci Adv	2022
36129839	Patient perspectives on testing for clonal hematopoiesis ofÂ indeterminate potential.	Blood Adv	2022
34743536	Clonal Hematopoiesis Is Associated With Higher Risk of Stroke.	Stroke	2022
34793200	Donor Clonal Hematopoiesis and Recipient Outcomes After Transplantation.	J Clin Oncol	2022
34855941	Association of clonal hematopoiesis with chronic obstructive pulmonary disease.	Blood	2022
34507355	Genomic profiling of a randomized trial of interferon-Î± vs hydroxyurea in MPN reveals mutation-specific responses.	Blood advances	2022
35015684	BCOR and BCORL1 Mutations Drive Epigenetic Reprogramming and Oncogenic Signaling by Unlinking PRC1.1 from Target Genes.	Blood Cancer Discov	2022
34698806	Dnmt3a-mutated clonal hematopoiesis promotes osteoporosis.	J Exp Med	2021
34019641	The clinical and functional effects of TERT variants in myelodysplastic syndrome.	Blood	2021
33637765	Distinct genetic pathways define pre-malignant versus compensatory clonal hematopoiesis in Shwachman-Diamond syndrome.	Nat Commun	2021
34106216	Association of Diet Quality With Prevalence of Clonal Hematopoiesis and Adverse Cardiovascular Events.	JAMA Cardiology	2021
34342642	Clonal hematopoiesis in patients receiving chimeric antigen receptor T-cell therapy.	Blood advances	2021
33054119	A deep molecular response of splenic marginal zone lymphoma to front-line checkpoint blockade.	Haematologica	2021
34663986	Distinction of lymphoid and myeloid clonal hematopoiesis.	Nat Med	2021
33106634	Cancer therapy shapes the fitness landscape of clonal hematopoiesis.	Nat Genet	2020
31714164	Myelodysplastic syndromes (MDS) occurring in Agent Orange exposed individuals carry a mutational spectrum similar to that of <i>de novo</i> MDS.	Leuk Lymphoma	2020
32097457	Stem cell donors should not be screened for clonal hematopoiesis.	Blood advances	2020
32150605	Identification of germline variants in adults with hemophagocytic lymphohistiocytosis.	Blood advances	2020
32540328	Safety evaluation of E12, W8, X17, and Y9 potatoes: Nutritional evaluation and 90-day subchronic feeding study in rats.	Regulatory Toxicology and Pharmacology	2020
32533060	Clonal hematopoiesis is associated with adverse outcomes in multiple myeloma patients undergoing transplant.	Nat Commun	2020
32961550	Contribution of clonal hematopoiesis to adult-onset hemophagocytic lymphohistiocytosis.	Blood	2020
33015529	Fitness Landscape of Clonal Hematopoiesis Under Selective Pressure of Immune Checkpoint Blockade.	JCO Precis Oncol	2020
31533061	Safety assessment of the biotechnologically produced human-identical milk oligosaccharide 3-Fucosyllactose (3-FL).	Food and Chemical Toxicology	2019
30715446	Premature Aging in Young Cancer Survivors.	Journal of the National Cancer Institute	2019
29724895	High <i>NPM1</i>-mutant allele burden at diagnosis predicts unfavorable outcomes in de novo AML.	Blood	2018
29954749	PPM1D-truncating mutations confer resistance to chemotherapy and sensitivity to PPM1D inhibition in hematopoietic cells.	Blood	2018
29703819	New Insights from Studies of Clonal Hematopoiesis.	Clin Cancer Res	2018
29326119	Association of mutations with morphological dysplasia in acute myeloid leukemia without 2016 WHO Classification-defined cytogenetic abnormalities.	Haematologica	2018
27834397	The genetics of myelodysplastic syndrome: from clonal haematopoiesis to secondary leukaemia.	Nature Reviews Cancer	2017
28636844	Clonal Hematopoiesis and Risk of Atherosclerotic Cardiovascular Disease.	N Engl J Med	2017
28370403	NPM1 mutation but not RUNX1 mutation or multilineage dysplasia defines a prognostic subgroup within de novo acute myeloid leukemia lacking recurrent cytogenetic abnormalities in the revised 2016 WHO classification.	American Journal of Hematology	2017
28446434	Donor-engrafted CHIP is common among stem cell transplant recipients with unexplained cytopenias.	Blood	2017
29296824	Systematic <i>STAT3</i> sequencing in patients with unexplained cytopenias identifies unsuspected large granular lymphocytic leukemia.	Blood Adv	2017
27241017	Detection of activating MAP2K1 mutations in atypical hairy cell leukemia and hairy cell leukemia variant.	Leukemia and Lymphoma	2017
28068180	Clonal Hematopoiesis Associated With Adverse Outcomes After Autologous Stem-Cell Transplantation for Lymphoma.	J Clin Oncol	2017