Author details

Full Name

Judith A Clements

Affiliation

ORCID

Career Start Year

1974

Papers

255

H Index

Expertise

CM4AI Collaborator

PMID	Paper Title	Journal Title	Published Year
36598826	The roles of proteases in prostate cancer.	IUBMB Life	2023
37945903	Characterizing prostate cancer risk through multi-ancestry genome-wide discovery of 187 novel risk variants.	Nat Genet	2023
37561382	Genomic and Phenotypic Biomarkers for Precision Medicine Guidance in Advanced Prostate Cancer.		2023
38076926	Unravelling the Role of Iroquois Homeobox 4 and its Interplay with Androgen Receptor in Prostate Cancer.		2023
36708740	GelMA and Biomimetic Culture Allow the Engineering of Mineralized, Adipose, and Tumor Tissue Human Microenvironments for the Study of Advanced Prostate Cancer In Vitro and In Vivo.		2023
37264224	Characterisation of cell lines derived from prostate cancer patients with localised disease.	Prostate Cancer Prostatic Dis	2023
37311464	Evaluating approaches for constructing polygenic risk scores for prostate cancer in men of African and European ancestry.	Am J Hum Genet	2023
37292833	Evaluating Approaches for Constructing Polygenic Risk Scores for Prostate Cancer in Men of African and European Ancestry.	medRxiv	2023
35102281	Remodelling of the tumour microenvironment by the kallikrein-related peptidases.	Nature Reviews Cancer	2022
34462519	A humanized orthotopic tumor microenvironment alters the bone metastatic tropism of prostate cancer cells.	Commun Biol	2021
33473200	Publisher Correction: Trans-ancestry genome-wide association meta-analysis of prostate cancer identifies new susceptibility loci and informs genetic risk prediction.	Nat Genet	2021
33572476	SWATH-MS Based Proteomic Profiling of Prostate Cancer Cells Reveals Adaptive Molecular Mechanisms in Response to Anti-Androgen Therapy.	Cancers	2021
34193425	In vitro engineering of a bone metastases model allows for study of the effects of antiandrogen therapies in advanced prostate cancer.	Science advances	2021
34085829	A Suite of Activity-Based Probes To Dissect the KLK Activome in Drug-Resistant Prostate Cancer.	Journal of the American Chemical Society	2021
34298795	Allele-Specific MicroRNA-Mediated Regulation of a Glycolysis Gatekeeper PDK1 in Cancer Metabolism.	Cancers	2021
33398198	Trans-ancestry genome-wide association meta-analysis of prostate cancer identifies new susceptibility loci and informs genetic risk prediction.	Nat Genet	2021
32514134	The effect of sample size on polygenic hazard models for prostate cancer.	Eur J Hum Genet	2020
31630475	The molecular function of kallikrein-related peptidase 14 demonstrates a key modulatory role in advanced prostate cancer.	Mol Oncol	2020
33255452	KLK4 Induces Anti-Tumor Effects in Human Xenograft Mouse Models of Orthotopic and Metastatic Prostate Cancer.	Cancers	2020
31044095	Engineering osteoblastic metastases to delineate the adaptive response of androgen-deprived prostate cancer in the bone metastatic microenvironment.	Bone Research	2019
31650320	Preface to "Proteases in Cancer Progression and Metastasis" special issue.	Cancer and Metastasis Reviews	2019
31659564	Beyond the biomarker role: prostate-specific antigen (PSA) in the prostate cancer microenvironment.	Cancer and Metastasis Reviews	2019
30396040	A 3D tumor microenvironment regulates cell proliferation, peritoneal growth and expression patterns.	Biomaterials	2019
30538273	Post-GWAS in prostate cancer: from genetic association to biological contribution.	Nature Reviews Cancer	2019
30538125	Prostate Cancer Risk-Associated Single-Nucleotide Polymorphism Affects Prostate-Specific Antigen Glycosylation and Its Function.	Clinical Chemistry	2019
30622367	Author Correction: Association analyses of more than 140,000 men identify 63 new prostate cancer susceptibility loci.	Nat Genet	2019
30705123	Integration of Two In-depth Quantitative Proteomics Approaches Determines the Kallikrein-related Peptidase 7 (KLK7) Degradome in Ovarian Cancer Cell Secretome.	Molecular and Cellular Proteomics	2019
30866453	Gamma-Tocotrienol Induces Apoptosis in Prostate Cancer Cells by Targeting the Ang-1/Tie-2 Signalling Pathway.	International Journal of Molecular Sciences	2019
31018918	MicroRNA-3162-5p-Mediated Crosstalk between Kallikrein Family Members Including Prostate-Specific Antigen in Prostate Cancer.	Clin Chem	2019
30683880	Shared heritability and functional enrichment across six solid cancers.	Nat Commun	2019
31400612	Microenvironment engineering of osteoblastic bone metastases reveals osteomimicry of patient-derived prostate cancer xenografts.	Biomaterials	2019
31101638	Emergence of MicroRNAs as Key Players in Cancer Cell Metabolism.	Clinical Chemistry	2019
31548585	Publisher Correction: Shared heritability and functional enrichment across six solid cancers.	Nat Commun	2019
29793440	Using high throughput microtissue culture to study the difference in prostate cancer cell behavior and drug response in 2D and 3D co-cultures.	BMC Cancer	2018
28714574	A humanised tissue-engineered bone model allows species-specific breast cancer-related bone metastasis in vivo.	Journal of Tissue Engineering and Regenerative Medicine	2018
29892050	Fine-mapping of prostate cancer susceptibility loci in a large meta-analysis identifies candidate causal variants.	Nat Commun	2018
29892016	Association analyses of more than 140,000 men identify 63 new prostate cancer susceptibility loci.	Nat Genet	2018
30114962	Kallikrein-related peptidases represent attractive therapeutic targets for ovarian cancer.	Expert Opinion on Therapeutic Targets	2018
30397198	Germline variation at 8q24 and prostate cancer risk in men of European ancestry.	Nat Commun	2018
30428629	Humanization of the Prostate Microenvironment Reduces Homing of PC3 Prostate Cancer Cells to Human Tissue-Engineered Bone.	Cancers (Basel)	2018
30337939	Association Analysis of a Microsatellite Repeat in the Gene With Prostate Cancer Risk, Aggressiveness and Survival.	Frontiers in Genetics	2018
30052511	Mining human cancer datasets for kallikrein expression in cancer: the 'KLK-CANMAP' Shiny web tool.	Biol Chem	2018
30287916	Kallikrein-related peptidases 4, 5, 6 and 7 regulate tumour-associated factors in serous ovarian cancer.	British Journal of Cancer	2018
29438364	Height, selected genetic markers and prostate cancer risk: results from the PRACTICAL consortium.	Br J Cancer	2018
29703916	A Plasma Biomarker Panel of Four MicroRNAs for the Diagnosis of Prostate Cancer.	Sci Rep	2018
29377712	Standard PREanalytical Code Version 3.0.	Biopreserv Biobank	2018
29321576	The Microwell-mesh: A high-throughput 3D prostate cancer spheroid and drug-testing platform.	Scientific Reports	2018
29321194	Polygenic hazard score to guide screening for aggressive prostate cancer: development and validation in large scale cohorts.	BMJ	2018
28315249	Determining Protease Substrates Within a Complex Protein Background Using the PROtein TOpography and Migration Analysis Platform (PROTOMAP).	Methods in Molecular Biology	2017
28510269	Kallikrein-related peptidase 4 induces cancer-associated fibroblast features in prostate-derived stromal cells.	Mol Oncol	2017