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Author Details

Zhiya Yu
Center for Cancer Research, National Cancer Institute, National Institutes of Health
1995
94
61
PMIDPaper TitleJournal TitlePublished Year
37377887Reprogramming of Tumor-reactive Tumor-infiltrating Lymphocytes to Human-induced Pluripotent Stem Cells.Cancer Res Commun2023
37377887Reprogramming of Tumor-reactive Tumor-infiltrating Lymphocytes to Human-induced Pluripotent Stem Cells.Cancer Res Commun2023
35113651Molecular signatures of antitumor neoantigen-reactive T cells from metastatic human cancers.Science2022
35749374Adoptive Cellular Therapy with Autologous Tumor-Infiltrating Lymphocytes and T-cell Receptor-Engineered T Cells Targeting Common p53 Neoantigens in Human Solid Tumors.Cancer Immunol Res2022
35926468Cancer genes disfavoring T cell immunity identified via integrated systems approach.Cell Rep2022
35113651Molecular signatures of antitumor neoantigen-reactive T cells from metastatic human cancers.Science2022
35749374Adoptive Cellular Therapy with Autologous Tumor-Infiltrating Lymphocytes and T-cell Receptor-Engineered T Cells Targeting Common p53 Neoantigens in Human Solid Tumors.Cancer Immunol Res2022
35926468Cancer genes disfavoring T cell immunity identified via integrated systems approach.Cell Rep2022
34168045Identification and Validation of T-cell Receptors Targeting <i>RAS</i> Hotspot Mutations in Human Cancers for Use in Cell-based Immunotherapy.Clin Cancer Res2021
34168045Identification and Validation of T-cell Receptors Targeting <i>RAS</i> Hotspot Mutations in Human Cancers for Use in Cell-based Immunotherapy.Clin Cancer Res2021
34526724An engineered IL-2 partial agonist promotes CD8<sup>+</sup> T cell stemness.Nature2021
34526724An engineered IL-2 partial agonist promotes CD8<sup>+</sup> T cell stemness.Nature2021
32231230Identification of Small Molecule Enhancers of Immunotherapy for Melanoma.Sci Rep2020
31959727Enhanced efficacy and limited systemic cytokine exposure with membrane-anchored interleukin-12 T-cell therapy in murine tumor models.J Immunother Cancer2020
32231230Identification of Small Molecule Enhancers of Immunotherapy for Melanoma.Sci Rep2020
31996390Antigen Experienced T Cells from Peripheral Blood Recognize p53 Neoantigens.Clin Cancer Res2020
33303615Stem-like CD8 T cells mediate response of adoptive cell immunotherapy against human cancer.Science2020
32516591Multi-phenotype CRISPR-Cas9 Screen Identifies p38 Kinase as a Target for Adoptive Immunotherapies.Cancer Cell2020
31996390Antigen Experienced T Cells from Peripheral Blood Recognize p53 Neoantigens.Clin Cancer Res2020
31959727Enhanced efficacy and limited systemic cytokine exposure with membrane-anchored interleukin-12 T-cell therapy in murine tumor models.J Immunother Cancer2020
33303615Stem-like CD8 T cells mediate response of adoptive cell immunotherapy against human cancer.Science2020
32516591Multi-phenotype CRISPR-Cas9 Screen Identifies p38 Kinase as a Target for Adoptive Immunotherapies.Cancer Cell2020
30694219T cells genetically engineered to overcome death signaling enhance adoptive cancer immunotherapy.J Clin Invest2019
31628526Antisense targeting of CD47 enhances human cytotoxic T-cell activity and increases survival of mice bearing B16 melanoma when combined with anti-CTLA4 and tumor irradiation.Cancer Immunol Immunother2019
31092734An effective mouse model for adoptive cancer immunotherapy targeting neoantigens.JCI Insight2019
30923193T cell stemness and dysfunction in tumors are triggered by a common mechanism.Science2019
30694219T cells genetically engineered to overcome death signaling enhance adoptive cancer immunotherapy.J Clin Invest2019
31405895Host conditioning with IL-1β improves the antitumor function of adoptively transferred T cells.J Exp Med2019
30778251The transcription factor c-Myb regulates CD8<sup>+</sup> T cell stemness and antitumor immunity.Nat Immunol2019
30714987Neoantigen screening identifies broad TP53 mutant immunogenicity in patients with epithelial cancers.J Clin Invest2019
31405895Host conditioning with IL-1β improves the antitumor function of adoptively transferred T cells.J Exp Med2019
31628526Antisense targeting of CD47 enhances human cytotoxic T-cell activity and increases survival of mice bearing B16 melanoma when combined with anti-CTLA4 and tumor irradiation.Cancer Immunol Immunother2019
30714987Neoantigen screening identifies broad TP53 mutant immunogenicity in patients with epithelial cancers.J Clin Invest2019
30778251The transcription factor c-Myb regulates CD8<sup>+</sup> T cell stemness and antitumor immunity.Nat Immunol2019
30923193T cell stemness and dysfunction in tumors are triggered by a common mechanism.Science2019
31092734An effective mouse model for adoptive cancer immunotherapy targeting neoantigens.JCI Insight2019
29562175Generation of Tumor Antigen-Specific iPSC-Derived Thymic Emigrants Using a 3D Thymic Culture System.Cell Rep2018
29669936Engineered T cells targeting E7 mediate regression of human papillomavirus cancers in a murine model.JCI Insight2018
29562175Generation of Tumor Antigen-Specific iPSC-Derived Thymic Emigrants Using a 3D Thymic Culture System.Cell Rep2018
29669936Engineered T cells targeting E7 mediate regression of human papillomavirus cancers in a murine model.JCI Insight2018
27803044Preclinical Evaluation of Chimeric Antigen Receptors Targeting CD70-Expressing Cancers.Clin Cancer Res2017
28935813ASXL3 Is a Novel Pluripotency Factor in Human Respiratory Epithelial Cells and a Potential Therapeutic Target in Small Cell Lung Cancer.Cancer Res2017
27803044Preclinical Evaluation of Chimeric Antigen Receptors Targeting CD70-Expressing Cancers.Clin Cancer Res2017
27965307Dual-specific Chimeric Antigen Receptor T Cells and an Indirect Vaccine Eradicate a Variety of Large Solid Tumors in an Immunocompetent, Self-antigen Setting.Clin Cancer Res2017
28935813ASXL3 Is a Novel Pluripotency Factor in Human Respiratory Epithelial Cells and a Potential Therapeutic Target in Small Cell Lung Cancer.Cancer Res2017
27965307Dual-specific Chimeric Antigen Receptor T Cells and an Indirect Vaccine Eradicate a Variety of Large Solid Tumors in an Immunocompetent, Self-antigen Setting.Clin Cancer Res2017
26701267Identification of T-cell Receptors Targeting KRAS-Mutated Human Tumors.Cancer Immunol Res2016
26731475The transcription factor BACH2 promotes tumor immunosuppression.J Clin Invest2016
27271569Constitutive Lck Activity Drives Sensitivity Differences between CD8+ Memory T Cell Subsets.J Immunol2016
27158840BACH2 regulates CD8(+) T cell differentiation by controlling access of AP-1 factors to enhancers.Nat Immunol2016
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Collaborators

National Cancer Institute, National Institutes of Health (NIH)
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University of Colorado School of Medicine
Co-authored papers 41
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Jonsson Comprehensive Cancer Center, University of California los angeles
Co-authored papers 8
National Cancer Institute
Co-authored papers 8
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Co-authored papers 5
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Co-authored papers 5
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Co-authored papers 5
Center for Cellular Engineering, NIH Clinical Center, National Institutes of Health
Co-authored papers 4
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Co-authored papers 4
Science Applications International Corporation/Frederick
Co-authored papers 4
College of Health and Life Sciences, Hamad Bin Khalifa University, Qatar Foundation
Co-authored papers 2
National Institute of Allergy and Infectious Diseases
Co-authored papers 2
Co-authored papers 2
Center for Cancer Research, National Cancer Institute
Co-authored papers 2
Stanford University School of Medicine
Co-authored papers 2
National Institute of Child Health and Development
Co-authored papers 2
National Cancer Institute, National Institutes of Health
Co-authored papers 2
Co-authored papers 2
National Eye Institute, National Institutes of Health
Co-authored papers 2
Johns Hopkins School of Medicine, National Cancer Institute, Princeton University, University of Colorado Anschutz Medical Campus, University of Pittsburgh, University of Washington
Co-authored papers 2
National Cancer Institute
Co-authored papers 2
Center for Cancer Research, National Cancer Institute, National Institutes of Health
Co-authored papers 2
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National Institute of Arthritis, National Institutes of Health
Co-authored papers 2
RIKEN Research Center for Allergy and Immunology
Co-authored papers 1
Chalmers University of Technology
Co-authored papers 1
and Blood Institute, National Institutes of Health
Co-authored papers 1
Jiangsu University Zhenjiang 212013
Co-authored papers 1