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Author Details

Leigh Thorne
1993
90
35
PMIDPaper TitleJournal TitlePublished Year
35129287Plastic bronchitis: Autopsy findings in the sudden death of a healthy pediatric patient with sickle cell disease.Pediatric Blood and Cancer2022
35816430Prevalence and Mechanisms of Mucus Accumulation in COVID-19 Lung Disease.Am J Respir Crit Care Med2022
35857635SARS-CoV-2 infection produces chronic pulmonary epithelial and immune cell dysfunction with fibrosis in mice.Sci Transl Med2022
36377074Generalized Modules for Membrane Antigens (GMMA), an outer membrane vesicle-based vaccine platform, for efficient viral antigen delivery.Journal of Extracellular Vesicles2022
34990404Rapid idiosyncratic mechanisms of clinical resistance to KRAS G12C inhibition.J Clin Invest2022
35217407Protease-anti-protease compartmentalization in SARS-CoV-2 ARDS: Therapeutic implications.eBioMedicine2022
35194605A model of persistent post SARS-CoV-2 induced lung disease for target identification and testing of therapeutic strategies.bioRxiv2022
32860343Decline in circulating viral and human tumor markers after resection of head and neck carcinoma.Head and Neck2021
34179214Fatal Pediatric COVID-19 Case With Seizures and Fulminant Cerebral Edema.Child Neurol Open2021
31894737Transmissible spongiform encephalopathy in goats: is PrP rapid test sensitivity affected by genotype?Journal of Veterinary Diagnostic Investigation2020
30930645DNA barcoding of British mosquitoes (Diptera, Culicidae) to support species identification, discovery of cryptic genetic diversity and monitoring invasive species.ZooKeys2019
29132993Re-evaluating the effect of Favipiravir treatment on rabies virus infection.Vaccine2019
31111687Incomplete inactivation of atypical scrapie following recommended autoclave decontamination procedures.Transboundary and Emerging Diseases2019
31053164Evidence for infection but not transmission of Zika virus by Aedes albopictus (Diptera: Culicidae) from Spain.Parasites and Vectors2019
29409530Frequency of breast cancer subtypes among African American women in the AMBER consortium.Breast Cancer Res2018
28859290Racial Differences in PAM50 Subtypes in the Carolina Breast Cancer Study.J Natl Cancer Inst2018
30408075Molecular characterisation of atypical BSE prions by mass spectrometry and changes following transmission to sheep and transgenic mouse models.PLoS ONE2018
29970149Assessment of vector competence of UK mosquitoes for Usutu virus of African origin.Parasites and Vectors2018
29480819Integrated RNA and DNA sequencing reveals early drivers of metastatic breast cancer.J Clin Invest2018
29745870Isolation, antigenicity and immunogenicity of Lleida bat lyssavirus.Journal of General Virology2018
29543916Correction: Molecular Subtypes in Head and Neck Cancer Exhibit Distinct Patterns of Chromosomal Gain and Loss of Canonical Cancer Genes.PLoS One2018
29543715Utilisation of Chimeric Lyssaviruses to Assess Vaccine Protection against Highly Divergent Lyssaviruses.Viruses2018
28610033Molecular approaches for blood meal analysis and species identification of mosquitoes (Insecta: Diptera: Culicidae) in rural locations in southern England, United Kingdom.Zootaxa2017
27825366L-BSE experimentally transmitted to sheep presents as a unique disease phenotype.Veterinary Research2016
26536169Comprehensive Molecular Characterization of Papillary Renal-Cell Carcinoma.N Engl J Med2016
26711328Performance of Three-Biomarker Immunohistochemistry for Intrinsic Breast Cancer Subtyping in the AMBER Consortium.Cancer Epidemiol Biomarkers Prev2016
27809975Detection of Theileria orientalis in mosquito blood meals in the United Kingdom.Veterinary Parasitology2016
27747159Two fatal herpesvirus cases: Treatable but easily missed diagnoses.IDCases2016
27640200Evidence of scrapie transmission to sheep via goat milk.BMC Veterinary Research2016
26061751Comprehensive, Integrative Genomic Analysis of Diffuse Lower-Grade Gliomas.N Engl J Med2015
25853789Ability of wild type mouse bioassay to detect bovine spongiform encephalopathy (BSE) in the presence of excess scrapie.Acta neuropathologica communications2015
26041899Does the Presence of Scrapie Affect the Ability of Current Statutory Discriminatory Tests To Detect the Presence of Bovine Spongiform Encephalopathy?Journal of Clinical Microbiology2015
25224251Alterations of LKB1 and KRAS and risk of brain metastasis: comprehensive characterization by mutation analysis, copy number, and gene expression in non-small-cell lung carcinoma.Lung Cancer2014
24257620Assessing the susceptibility of transgenic mice overexpressing deer prion protein to bovine spongiform encephalopathy.Journal of Virology2014
23701907Prediction of lung cancer histological types by RT-qPCR gene expression in FFPE specimens.J Mol Diagn2013
22583114Validation of interobserver agreement in lung cancer assessment: hematoxylin-eosin diagnostic reproducibility for non-small cell lung cancer: the 2004 World Health Organization classification and therapeutically relevant subsets.Arch Pathol Lab Med2013
23472112Strain typing of classical scrapie by transgenic mouse bioassay using protein misfolding cyclic amplification to replace primary passage.PLoS ONE2013
23175776PPARγ coactivator-1α contributes to exercise-induced regulation of intramuscular lipid droplet programming in mice and humans.Journal of Lipid Research2013
23651710Evidence of effective scrapie transmission via colostrum and milk in sheep.BMC Veterinary Research2013
23451093Molecular subtypes in head and neck cancer exhibit distinct patterns of chromosomal gain and loss of canonical cancer genes.PLoS One2013
22013047The oral secretion of infectious scrapie prions occurs in preclinical sheep with a range of PRNP genotypes.Journal of Virology2012
22590557Differential pathogenesis of lung adenocarcinoma subtypes involving sequence mutations, copy number, chromosomal instability, and methylation.PLoS One2012
22735904Different cellular p16(INK4a) localisation may signal different survival outcomes in head and neck cancer.Br J Cancer2012
22915693Infectious titres of sheep scrapie and bovine spongiform encephalopathy agents cannot be accurately predicted from quantitative laboratory test results.Journal of General Virology2012
22410851Epstein-Barr virus infection is common in inflamed gastrointestinal mucosa.Digestive Diseases and Sciences2012
23153009In vitro amplification of ovine prions from scrapie-infected sheep from Great Britain reveals distinct patterns of propagation.BMC Veterinary Research2012
23116457The interpretation of disease phenotypes to identify TSE strains following murine bioassay: characterisation of classical scrapie.Veterinary Research2012
21919992Use of murine bioassay to resolve ovine transmissible spongiform encephalopathy cases showing a bovine spongiform encephalopathy molecular profile.Brain Pathology2012
21987099Differentiating ovine BSE from CH1641 scrapie by serial protein misfolding cyclic amplification.Molecular Biotechnology2012
21592355Detection of prions in the faeces of sheep naturally infected with classical scrapie.Veterinary Research2011
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Center for Cancer Research, University of Tennessee Health Science Center
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Uniformed Services University of the Health Sciences
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University of Illinois at Urbana-Champaign
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Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill
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Johns Hopkins Bloomberg School of Public Health
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Lineberger Cancer Center, University of North Carolina
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University of North Carolina
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Canada British Columbia Cancer Research Centre, University of British Columbia
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University of North Carolina at Chapel Hill
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Broad Institute
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Nationwide Children's Hospital
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Present address: Dxige Research Inc.
Co-authored papers 2
Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill
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