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Author Details

J Crawford Downs
University of Alabama at Birmingham
1987
102
45
PMIDPaper TitleJournal TitlePublished Year
37149973Morphological and biomechanical analyses of the human healthy and glaucomatous aqueous outflow pathway: Imaging-to-modeling.Comput Methods Programs Biomed2023
35026624Finite element modeling of the complex anisotropic mechanical behavior of the human sclera and pia mater.Comput Methods Programs Biomed2022
35660943Biomechanics of human trabecular meshwork in healthy and glaucoma eyes via dynamic Schlemm's canal pressurization.Comput Methods Programs Biomed2022
35660940Modeling the biomechanics of the conventional aqueous outflow pathway microstructure in the human eye.Comput Methods Programs Biomed2022
36497183Modeling the Endothelial Glycocalyx Layer in the Human Conventional Aqueous Outflow Pathway.Cells2022
36074454Ocular Pulse Amplitude Correlates With Ocular Rigidity at Native IOP Despite the Variability in Intraocular Pulse Volume With Each Heartbeat.Transl Vis Sci Technol2022
36354583The Effect of Intraocular Pressure Load Boundary on the Biomechanics of the Human Conventional Aqueous Outflow Pathway.Bioengineering (Basel)2022
36294371Viscoelastic Biomechanical Properties of the Conventional Aqueous Outflow Pathway Tissues in Healthy and Glaucoma Human Eyes.J Clin Med2022
36255364Relative Contributions of Intraocular and Cerebrospinal Fluid Pressures to the Biomechanics of the Lamina Cribrosa and Laminar Neural Tissues.Invest Ophthalmol Vis Sci2022
35144807Ocular biomechanics during improvised explosive device blast: A computational study using eye-specific models.Injury2022
35331675Unmet Needs in the Detection, Diagnosis, Monitoring, Treatment, and Understanding of Primary Open-Angle Glaucoma: A Position Statement of the American Glaucoma Society and the American Society of Cataract and Refractive Surgery.Ophthalmol Glaucoma2022
34245889Modeling the biomechanics of the lamina cribrosa microstructure in the human eye.Acta Biomater2021
33516762Histologic validation of optical coherence tomography-based three-dimensional morphometric measurements of the human optic nerve head: Methodology and preliminary results.Exp Eye Res2021
34375590Strain by virtual extensometers and video-imaging optical coherence tomography as a repeatable metric for IOP-Induced optic nerve head deformations.Exp Eye Res2021
34598082Ocular biomechanics due to ground blast reinforcement.Comput Methods Programs Biomed2021
32492113Intra-Subject Variability and Diurnal Cycle of Ocular Perfusion Pressure as Characterized by Continuous Telemetry in Nonhuman Primates.Invest Ophthalmol Vis Sci2020
32051652A Mesh-Free Approach to Incorporate Complex Anisotropic and Heterogeneous Material Properties into Eye-Specific Finite Element Models.Comput Methods Appl Mech Eng2020
32097479Diurnal Cycle of Translaminar Pressure in Nonhuman Primates Quantified With Continuous Wireless Telemetry.Invest Ophthalmol Vis Sci2020
33240571Quantification of Translaminar Pressure Gradient (TLPG) With Continuous Wireless Telemetry in Nonhuman Primates (NHPs).Transl Vis Sci Technol2020
33074300Effect of Body Position on Intraocular Pressure (IOP), Intracranial Pressure (ICP), and Translaminar Pressure (TLP) Via Continuous Wireless Telemetry in Nonhuman Primates (NHPs).Invest Ophthalmol Vis Sci2020
33262420Comparison of extraocular and intraocular pressure transducers for measurement of transient intraocular pressure fluctuations using continuous wireless telemetry.Sci Rep2020
31170817Cyclic Pattern of Intraocular Pressure (IOP) and Transient IOP Fluctuations in Nonhuman Primates Measured with Continuous Wireless Telemetry.Curr Eye Res2019
31799505Acute Stress Increases Intraocular Pressure in Nonhuman Primates.Ophthalmol Glaucoma2019
30153437The Magnitude of Intraocular Pressure Elevation Associated with Eye Rubbing.Ophthalmology2019
31529079Effect of Anesthesia on Intraocular Pressure Measured With Continuous Wireless Telemetry in Nonhuman Primates.Invest Ophthalmol Vis Sci2019
31212310Transient Intraocular Pressure Fluctuations: Source, Magnitude, Frequency, and Associated Mechanical Energy.Invest Ophthalmol Vis Sci2019
31598625The Relationship Between Scleral Strain Change and Differential Cumulative Intraocular Pressure Exposure in the Nonhuman Primate Chronic Ocular Hypertension Model.Invest Ophthalmol Vis Sci2019
30208417IOP, IOP Transient Impulse, Ocular Perfusion Pressure, and Mean Arterial Pressure Relationships in Nonhuman Primates Instrumented With Telemetry.Invest Ophthalmol Vis Sci2018
30025140A Novel Tree Shrew (Tupaia belangeri) Model of Glaucoma.Invest Ophthalmol Vis Sci2018
27898470Lamina cribrosa in glaucoma.Curr Opin Ophthalmol2017
29228251The Magnitude and Time Course of IOP Change in Response to Body Position Change in Nonhuman Primates Measured Using Continuous IOP Telemetry.Invest Ophthalmol Vis Sci2017
28660275The Magnitude of Hypotony and Time Course of Intraocular Pressure Recovery Following Anterior Chamber Cannulation in Nonhuman Primates.Invest Ophthalmol Vis Sci2017
28738420Variation in the Three-Dimensional Histomorphometry of the Normal Human Optic Nerve Head With Age and Race: Lamina Cribrosa and Peripapillary Scleral Thickness and Position.Invest Ophthalmol Vis Sci2017
26939754Image-based quantification of fiber alignment within electrospun tissue engineering scaffolds is related to mechanical anisotropy.J Biomed Mater Res A2016
27942258Measuring Mean Cup Depth in the Optic Nerve Head.Comput Aided Des Appl2016
27196306Nanofiber Alignment Regulates NIH3T3 Cell Orientation and Cytoskeletal Gene Expression on Electrospun PCL+Gelatin Nanofibers.PLoS One2016
25819451Optic nerve head biomechanics in aging and disease.Exp Eye Res2015
26658503High-Magnitude and/or High-Frequency Mechanical Strain Promotes Peripapillary Scleral Myofibroblast Differentiation.Invest Ophthalmol Vis Sci2015
26352161The Thrombospondin1-TGF-β Pathway and Glaucoma.J Ocul Pharmacol Ther2015
26641545The Connective Tissue Components of Optic Nerve Head Cupping in Monkey Experimental Glaucoma Part 1: Global Change.Invest Ophthalmol Vis Sci2015
26720486Physical Factors Affecting Outflow Facility Measurements in Mice.Invest Ophthalmol Vis Sci2015
26216571IOP telemetry in the nonhuman primate.Exp Eye Res2015
25711640Peripapillary choroidal thickness variation with age and race in normal eyes.Invest Ophthalmol Vis Sci2015
25650423Lamina cribrosa microarchitecture in normal monkey eyes part 1: methods and initial results.Invest Ophthalmol Vis Sci2015
25782403Schiotz tonometry accurately measures intraocular pressure in Boston type 1 keratoprosthesis eyes.Cornea2015
23684352Material properties of the posterior human sclera.J Mech Behav Biomed Mater2014
25414182Variation of laminar depth in normal eyes with age and race.Invest Ophthalmol Vis Sci2014
25405660The promise of prediction: biomechanical analyses in neuro-ophthalmology.J Neuroophthalmol2014
25237162Human scleral structural stiffness increases more rapidly with age in donors of African descent compared to donors of European descent.Invest Ophthalmol Vis Sci2014
25190652Age-related differences in longitudinal structural change by spectral-domain optical coherence tomography in early experimental glaucoma.Invest Ophthalmol Vis Sci2014
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Collaborators

Heersink School of Medicine, University of Alabama-Birmingham
Co-authored papers 34
Heersink School of Medicine, University of Alabama-Birmingham
Co-authored papers 15
Singapore Eye Research Institute
Co-authored papers 12
University of Pittsburgh
Co-authored papers 10
University of Alabama at Birmingham
Co-authored papers 8
Perelman School of Medicine, University of Pennsylvania
Co-authored papers 7
University of Pittsburgh
Co-authored papers 5
University of Alabama at Birmingham
Co-authored papers 5
University of Wisconsin-Madison
Co-authored papers 5
University of Washington
Co-authored papers 4
University of Washington
Co-authored papers 4
University of Alabama at Birmingham
Co-authored papers 4
University of Alabama at Birmingham
Co-authored papers 4
University of Alabama at Birmingham
Co-authored papers 4
Universite de la Polynesie francaise
Co-authored papers 3
Heersink School of Medicine, University of Alabama at Birmingham
Co-authored papers 3
University of Alabama at Birmingham
Co-authored papers 3
University
Co-authored papers 2
Co-authored papers 2
Mettapracharak (Wat Rai Khing) Hospital
Co-authored papers 1
Medical College of Wisconsin
Co-authored papers 1
Duke University
Co-authored papers 1
University of Alabama at Birmingham
Co-authored papers 1
Co-authored papers 1
Imperial College London
Co-authored papers 1