Author details

Full Name

Johan Weigelt

Affiliation

Karolinska Institutet

ORCID

Career Start Year

1996

Papers

H Index

Expertise

CM4AI Collaborator

Andrej Sali (CM4AI)

PMID	Paper Title	Journal Title	Published Year
23742272	PARP inhibitor with selectivity toward ADP-ribosyltransferase ARTD3/PARP3.	ACS Chem Biol	2013
24188023	Chemical probes to study ADP-ribosylation: synthesis and biochemical evaluation of inhibitors of the human ADP-ribosyltransferase ARTD3/PARP3.	J Med Chem	2013
22343925	Family-wide chemical profiling and structural analysis of PARP and tankyrase inhibitors.	Nat Biotechnol	2012
22823910	Discovery of ligands for ADP-ribosyltransferases via docking-based virtual screening.	J Med Chem	2012
21439891	Towards new business models for R&D for novel antibiotics.	Drug Resist Updat	2011
21308845	A secretory system for bacterial production of high-profile protein targets.	Protein Sci	2011
20359538	A software tool to accelerate design of protein constructs for recombinant expression.	Protein Expr Purif	2010
20565110	Structural basis for the interaction between tankyrase-2 and a potent Wnt-signaling inhibitor.	J Med Chem	2010
20191434	Open-access public-private partnerships to enable drug discovery--new approaches.	IDrugs	2010
20211166	Structural genomics-impact on biomedicine and drug discovery.	Exp Cell Res	2010
19244245	The DEXD/H-box RNA helicase DDX19 is regulated by an {alpha}-helical switch.	J Biol Chem	2009
19721463	The case for open-access chemical biology. A strategy for pre-competitive medicinal chemistry to promote drug discovery.	EMBO Rep	2009
19354255	Structural basis for inhibitor specificity in human poly(ADP-ribose) polymerase-3.	J Med Chem	2009
18171622	The use of systematic N- and C-terminal deletions to promote production and structural studies of recombinant proteins.	Protein Expr Purif	2008
18235434	Protein production and purification.	Nat Methods	2008
18436240	Zinc binding catalytic domain of human tankyrase 1.	J Mol Biol	2008
17982461	In situ proteolysis for protein crystallization and structure determination.	Nat Methods	2007
17035505	Chemical screening methods to identify ligands that promote protein stability, protein crystallization, and structure determination.	Proc Natl Acad Sci U S A	2006
15012988	Mechanism of action of pyridazine analogues on protein tyrosine phosphatase 1B (PTP1B).	Bioorg Med Chem Lett	2004
11890787	Site-selective screening by NMR spectroscopy with labeled amino acid pairs.	J Am Chem Soc	2002
12470259	Site-selective labeling strategies for screening by NMR.	Comb Chem High Throughput Screen	2002
12018484	Backbone 1H, 13C and 15N resonance assignment of the N-terminal 24 kDa fragment of the gyrase B subunit from E. coli.	J Biomol NMR	2002
11965396	Structure-based screening and design in drug discovery.	Drug Discov Today	2002
11574466	NMR structure of the LCCL domain and implications for DFNA9 deafness disorder.	EMBO J	2001
11352721	Solution structure of the DNA binding domain of the human forkhead transcription factor AFX (FOXO4).	Biochemistry	2001
10921784	1H, 13C and 15N resonance assignments of the DNA binding domain of the human forkhead transcription factor AFX.	J Biomol NMR	2000
10404597	NMR structure of the N-terminal domain of E. coli DnaB helicase: implications for structure rearrangements in the helicase hexamer.	Structure	1999
9679300	Backbone NMR assignments and secondary structure of the N-terminal domain of DnaB helicase from E. coli.	J Biomol NMR	1998
9835050	Spin-state selection filters for the measurement of heteronuclear one-bond coupling constants.	J Biomol NMR	1998
9070233	Precise limits of the N-terminal domain of DnaB helicase determined by NMR spectroscopy.	Biochem Biophys Res Commun	1997
8819765	Removal of zero-quantum coherence in protein NMR spectra using SESAM decoupling and suppression of decoupling sidebands.	J Magn Reson B	1996

1 - 31 of 31

Lester G Carter

Stanford University

Career Start Year 2004

Number of shared co-authors 13

Ronald D Seidel

Albert Einstein College of Medicine

Career Start Year 2001

Number of shared co-authors 6

Rodrigo J Carbajo

Oncology R&D

Career Start Year 1997

Number of shared co-authors 1

Witek Kwiatkowski

Swiss Federal Institute of Technology

Career Start Year 1996

Number of shared co-authors 1

Roberto Sanchez

Department of Pharmacological Sciences, Icahn School of Medicine at Mount Sinai

Career Start Year 1996

Number of shared co-authors 6

Yuanpeng J Huang

Center for Advanced Biotechnology and Medicine, The State University of New Jersey

Career Start Year 1996

Number of shared co-authors 24

Volker D??tsch

Institute for Biophysical Chemistry, Goethe-University

Career Start Year 1995

Number of shared co-authors 4

Mark W Maciejewski

University of Connecticut School of Medicine

Career Start Year 1995

Number of shared co-authors 2

Ram??n Campos-Olivas

Spanish National Cancer Research Centre (CNIO)

Career Start Year 1995

Number of shared co-authors 4

Antonio Pineda-Lucena

Instituto de Investigacion Sanitaria La Fe

Career Start Year 1994

Number of shared co-authors 5

John R Cort

Pacific Northwest National Laboratory

Career Start Year 1994

Number of shared co-authors 23

Diana R Tomchick

University of Texas Southwestern Medical Center

Career Start Year 1993

Number of shared co-authors 2

Michael A Kennedy

Miami University

Career Start Year 1993

Number of shared co-authors 24

Michael Sattler

Technical University of Munich, Institute of Structural Biology

Career Start Year 1991

Number of shared co-authors 3

Gye Won Han

Bridge Institute, University of Southern California

Career Start Year 1991

Number of shared co-authors 6

Hartmut Oschkinat

Leibniz-Forschungsinstitut fur Molekulare Pharmakologie

Career Start Year 1988

Number of shared co-authors 5

Geerten W Vuister

Leicester Institute of Structural and Chemical Biology, University of Leicester

Career Start Year 1988

Number of shared co-authors 8

Paul C Driscoll

The Francis Crick Institute

Career Start Year 1987

Number of shared co-authors 3

Thomas A Frenkiel

The Medical Research Council Biomedical NMR Centre, The Francis Crick Institute

Career Start Year 1984

Number of shared co-authors 2

Lu-Yun Lian

Institute of Systems, The University of Liverpool

Career Start Year 1984

Number of shared co-authors 3

David Neuhaus

Medical Research Council - Laboratory of Molecular Biology

Career Start Year 1984

Number of shared co-authors 2

Mike P Williamson

The University of Sheffield

Career Start Year 1982

Number of shared co-authors 2

Walter J Chazin

and Center for Structural Biology, Vanderbilt University

Career Start Year 1982

Number of shared co-authors 6

Ruben Abagyan

Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California

Career Start Year 1981

Number of shared co-authors 4

Peter Bayer

University of Duisburg-Essen

Career Start Year 1981

Number of shared co-authors 2

Angela M Gronenborn

University of Pittsburgh

Career Start Year 1980

Number of shared co-authors 3

Tom L Blundell

Heartand Lung Research Institute, University of Cambridge

Career Start Year 1971

Number of shared co-authors 3

David Cowburn

Albert Einstein College of Medicine

Career Start Year 1969

Number of shared co-authors 3

John L Markley

University of Wisconsin-Madison

Career Start Year 1967

Number of shared co-authors 10

Jens Meiler

Vanderbilt University

Career Start Year 1954

Number of shared co-authors 6

row(s) 1 - 30 of 30

P??r Nordlund

Karolinska Institutet, BioClinicum J6

Co-authored papers 4

Susanne Gr??slund

Karolinska Institutet

Co-authored papers 4

Aled M Edwards

University of Toronto

Co-authored papers 3

Cheryl H Arrowsmith

University of Toronto

Co-authored papers 3

Raymond Hui

University of Toronto

Co-authored papers 3

Alexei Savchenko

University of Toronto

Co-authored papers 2

Youngchang Kim

Argonne National Laboratory

Co-authored papers 2

Adelinda Yee

University of Toronto

Co-authored papers 2

Andrzej Joachimiak

Center for Structural Biology of Infectious Diseases, University of Chicago

Co-authored papers 2

Thomas Helleday

The University of Sheffield

Co-authored papers 2

Sirano Dhe-Paganon

Dana-Farber Cancer Institute

Co-authored papers 2

Hee-Won Park

Kangwon National University College of Medicine

Co-authored papers 2

Rong Xiao

School of Public Health, Capital Medical University

Co-authored papers 1

Raymond C Stevens

iHuman Institute, ShanghaiTech University

Co-authored papers 1

Mei Jiang

The University of Texas MD Anderson Cancer Center

Co-authored papers 1

Kristin C Gunsalus

Center for Genomics and Systems Biology, New York University Abu Dhabi (NYUAD)

Co-authored papers 1

Alex Ignatchenko

European Bioinformatics Institute (EMBL-EBI)

Co-authored papers 1

Masayori Inouye

Robert Wood Johnson Medical School, Rutgers University

Co-authored papers 1

Gaetano T Montelione

Rensselaer Polytechnic Institute

Co-authored papers 1

Maksymilian Chruszcz

University of South Carolina, Michigan State University

Co-authored papers 1

Ritu Shastry

Co-authored papers 1

Opher Gileadi

Structural Genomics Consortium Karolinska Institute Stockholm Sweden.

Co-authored papers 1

Zihe Rao

Nankai University

Co-authored papers 1

Ian A Wilson

The Scripps Research Institute, USA The Skaggs Institute for Chemical Biology

Co-authored papers 1

Kellie Cunningham

Co-authored papers 1

Yang Shen

National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Co-authored papers 1

F W Studier

Brookhaven National Laboratory

Co-authored papers 1

Olga Loseva

Karolinska Institutet

Co-authored papers 1

Geoffrey S Waldo

Los Alamos National Laboratory

Co-authored papers 1

Yufeng Tong

University of Windsor

Co-authored papers 1

1 - 30

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