Author details

Full Name

William Marston Linehan

Affiliation

ORCID

Career Start Year

1971

Papers

732

H Index

133

Expertise

CM4AI Collaborator

PMID	Paper Title	Journal Title	Published Year
36789136	Automatic segmentation of clear cell renal cell tumors, kidney, and cysts in patients with von Hippel-Lindau syndrome using U-net architecture on magnetic resonance images.	ArXiv	2023
36302175	A Phase II Trial of Guadecitabine in Children and Adults with SDH-Deficient GIST, Pheochromocytoma, Paraganglioma, and HLRCC-Associated Renal Cell Carcinoma.	Clin Cancer Res	2023
36207629	Role of ultra-high b-value DWI in the imaging of hereditary leiomyomatosis and renal cell carcinoma (HLRCC).	Abdom Radiol (NY)	2023
38020527	Preoperative Renal Parenchyma Volume as a Predictor of Kidney Function Following Nephrectomy of Complex Renal Masses.		2023
38010527	The kidney imaging surveillance scoring system (KISSS): using qualitative MRI features to predict growth rate of renal tumors in patients with von-Hippel Lindau (VHL) syndrome.		2023
37561409	Cryptic splice mutation in the fumarate hydratase gene in patients with clinical manifestations of Hereditary Leiomyomatosis and Renal Cell Cancer.	Hum Mol Genet	2023
37778955	Outcomes of and indications for renal transplantation in patients with von Hippel Lindau disease.		2023
37095531	High-throughput and targeted drug screens identify pharmacological candidates against MiT-translocation renal cell carcinoma.	J Exp Clin Cancer Res	2023
36713582	Targeting mutant p53-R248W reactivates WT p53 function and alters the onco-metabolic profile.	Front Oncol	2023
36513625	A diagnosis of Birt-Hogg-DubÃ© syndrome in individuals with Smith-Magenis syndrome: Recommendation for cancer screening.	Am J Med Genet A	2023
37331486	PRDM10 RCC: A Birt-Hogg-DubÃ©-like Syndrome Associated With Lipoma and Highly Penetrant, Aggressive Renal Tumors Morphologically Resembling Type 2 Papillary Renal Cell Carcinoma.	Urology	2023
37018064	Proteostasis Modulation in Germline Missense von Hippel Lindau Disease.	Clin Cancer Res	2023
36495949	Comparison of Race-Based and Non-Race-Based Glomerular Filtration Rate Equations for the Assessment of Renal Functional Risk Before Nephrectomy.		2023
37453304	Radiologic reporting of MRI-proven thoracolumbar epidural metastases on body CT: 12-Year single-institution experience.	Clin Imaging	2023
37452654	ANGPTL2-mediated epigenetic repression of MHC-I in tumor cells accelerates tumor immune evasion.		2023
37384546	Complications after Nephron-sparing Interventions for Renal Tumors: Imaging Findings and Management.	Radiographics	2023
37380769	Reprogramming tumour-associated macrophages to outcompete cancer cells.		2023
37182269	Comparative analyses define differences between BHD-associated renal tumour and sporadic chromophobe renal cell carcinoma.	EBioMedicine	2023
36855860	Deep learning-based decision forest for hereditary clear cell renal cell carcinoma segmentation on MRI.	Med Phys	2023
37353242	EDITORIAL COMMENT.		2023
37037679	A novel multiplex score to predict outcomes of partial nephrectomy for multiple tumors.		2023
36987696	TFEB and TFE3 drive kidney cystogenesis andÂ tumorigenesis.	EMBO Mol Med	2023
35070081	Seventh BHD international symposium: recent scientific and clinical advancement.	Oncotarget	2022
35396773	Targeting chemoresistance in Xp11.2 translocation renal cell carcinoma using a novel polyamide-chlorambucil conjugate.	Cancer Science	2022
36040304	Resolving Enantiomers of 2-Hydroxy Acids by Nuclear Magnetic Resonance.	Analytical Chemistry	2022
36093377	TEMPOL inhibits SARS-CoV-2 replication and development of lung disease in the Syrian hamster model.	iScience	2022
35754026	Inhibition of HSP 90 is associated with potent anti-tumor activity in Papillary Renal Cell Carcinoma.	J Exp Clin Cancer Res	2022
35874919	Single-cell transcriptomes underscore genetically distinct tumor characteristics and microenvironment for hereditary kidney cancers.	iScience	2022
35869307	An MRI-based radiomics model to predict clear cell renal cell carcinoma growth rate classes in patients with von Hippel-Lindau syndrome.	Abdom Radiol (NY)	2022
35681624	A Histone Deacetylase Inhibitor Induces Acetyl-CoA Depletion Leading to Lethal Metabolic Stress in RAS-Pathway Activated Cells.	Cancers (Basel)	2022
35474866	MPA<sub>PASS</sub> software enables stitched multiplex, multidimensional EV repertoire analysis and a standard framework for reporting bead-based assays.	Cell Rep Methods	2022
36190452	Conditional Covalent Lethality Driven by Oncometabolite Accumulation.	ACS Chemical Biology	2022
35469800	Differential VHL Mutation Patterns in Bilateral Clear Cell RCC Distinguishes Between Independent Primary Tumors and Contralateral Metastatic Disease.	Urology	2022
33846112	Using Prostate Imaging-Reporting and Data System (PI-RADS) Scores to Select an Optimal Prostate Biopsy Method: A Secondary Analysis of the Trio Study.	Eur Urol Oncol	2022
33067352	A germline 1;3 translocation disrupting the gene: a novel genetic cause for von Hippel-Lindau.	Journal of Medical Genetics	2022
35223446	Tumor-Infiltrating Myeloid Cells Co-Express TREM1 and TREM2 and Elevated TREM-1 Associates With Disease Progression in Renal Cell Carcinoma.	Front Oncol	2022
34818478	Belzutifan for Renal Cell Carcinoma in von Hippel-Lindau Disease.	N Engl J Med	2021
32359162	Summary From the First Kidney Cancer Research Summit, September 12-13, 2019: A Focus on Translational Research.	J Natl Cancer Inst	2021
34171743	A deep-learning based artificial intelligence (AI) approach for differentiation of clear cell renal cell carcinoma from oncocytoma on multi-phasic MRI.	Clin Imaging	2021
34058014	Differences in risk factors for molecular subtypes of clear cell renal cell carcinoma.	Int J Cancer	2021
33527590	Characterization of genetically defined sporadic and hereditary type 1 papillary renal cell carcinoma cell lines.	Genes Chromosomes Cancer	2021
34108512	Real-Time insight into in vivo redox status utilizing hyperpolarized [1-<sup>13</sup>C] N-acetyl cysteine.	Sci Rep	2021
33675279	Comprehensive characterization of Alu-mediated breakpoints in germline VHL gene deletions and rearrangements in patients from 71 VHL families.	Human Mutation	2021
33670168	Precision Surgery and Kidney Cancer: Knowledge of Genetic Alterations Influences Surgical Management.	Genes	2021
33665124	Macronodular adrenal hyperplasia masquerading as an upper pole renal mass.	Urol Case Rep	2021
33831400	X-Capsular Incision for Tumor Enucleation (X-CITE)-Technique: A Method to Maximize Renal Parenchymal Preservation for Completely Endophytic Renal Tumors.	Urology	2021
33512384	Therapeutic inhibition of HIF-2Î± reverses polycythemia and pulmonary hypertension in murine models of human diseases.	Blood	2021
34343338	Genetic risk assessment for hereditary renal cell carcinoma: Clinical consensus statement.	Cancer	2021
34083449	Fe-S cofactors in the SARS-CoV-2 RNA-dependent RNA polymerase are potential antiviral targets.	Science	2021
33974442	Prognostic Factors in De Novo Metastatic Renal Cell Carcinoma: A Report From the Latin American Renal Cancer Group.	JCO Glob Oncol	2021