|
| 38072051 | Cryo-EM structures of the D290V mutant of the hnRNPA2 low-complexity domain suggests how D290V affects phase separation and aggregation. | J Biol Chem | 2024 |
| 36757890 | Small molecules disaggregate alpha-synuclein and prevent seeding from patient brain-derived fibrils. | Proc Natl Acad Sci U S A | 2023 |
| 38077690 | Fibril structures of TFG protein mutants validate the identification of TFG as a disease-related amyloid protein by the IMPAcT method. | PNAS Nexus | 2023 |
| 37801475 | Structure-based design of nanobodies that inhibit seeding of Alzheimer's patient-extracted tau fibrils. | Proc Natl Acad Sci U S A | 2023 |
| 37185252 | Low complexity domains of the nucleocapsid protein of SARS-CoV-2 form amyloid fibrils. | Nat Commun | 2023 |
| 37398204 | CRISPR screens in iPSC-derived neurons reveal principles of tau proteostasis. | bioRxiv | 2023 |
| 34954854 | Atomic view of an amyloid dodecamer exhibiting selective cellular toxic vulnerability in acute brain slices. | Protein Sci | 2022 |
| 35405097 | Bioinformatic identification of previously unrecognized amyloidogenic proteins. | J Biol Chem | 2022 |
| 35377792 | Cryo-EM structure of RNA-induced tau fibrils reveals a small C-terminal core that may nucleate fibril formation. | Proc Natl Acad Sci U S A | 2022 |
| 35344984 | Amyloid fibrils in FTLD-TDP are composed of TMEM106B and not TDP-43. | Nature | 2022 |
| 35637421 | Identifying amyloid-related diseases by mapping mutations in low-complexity protein domains to pathologies. | Nat Struct Mol Biol | 2022 |
| 36420821 | Amyloid nomenclature 2022: update, novel proteins, and recommendations by the International Society of Amyloidosis (ISA) Nomenclature Committee. | Amyloid | 2022 |
| 35969734 | De novo designed protein inhibitors of amyloid aggregation and seeding. | Proc Natl Acad Sci U S A | 2022 |
| 35988647 | Micro-electron diffraction structure of the aggregation-driving N terminus of Drosophila neuronal protein Orb2A reveals amyloid-like β-sheets. | J Biol Chem | 2022 |
| 36091211 | The rippled β-sheet layer configuration-a novel supramolecular architecture based on predictions by Pauling and Corey. | Chem Sci | 2022 |
| 36114178 | Structure-based discovery of small molecules that disaggregate Alzheimer's disease tissue derived tau fibrils in vitro. | Nat Commun | 2022 |
| 35132852 | Extended β-Strands Contribute to Reversible Amyloid Formation. | ACS Nano | 2022 |
| 33372136 | Intrinsic electronic conductivity of individual atomically resolved amyloid crystals reveals micrometer-long hole hopping via tyrosines. | Proc Natl Acad Sci U S A | 2021 |
| 33688654 | Inhibition of amyloid formation of the Nucleoprotein of SARS-CoV-2. | bioRxiv | 2021 |
| 34518699 | Cryo-EM structures of hIAPP fibrils seeded by patient-extracted fibrils reveal new polymorphs and conserved fibril cores. | Nat Struct Mol Biol | 2021 |
| 34537246 | Prevalence and species distribution of the low-complexity, amyloid-like, reversible, kinked segment structural motif in amyloid-like fibrils. | J Biol Chem | 2021 |
| 34534463 | The expanding amyloid family: Structure, stability, function, and pathogenesis. | Cell | 2021 |
| 32541896 | Cryo-EM structure and inhibitor design of human IAPP (amylin) fibrils. | Nat Struct Mol Biol | 2020 |
| 31895037 | Inhibition of synucleinopathic seeding by rationally designed inhibitors. | Elife | 2020 |
| 32015135 | The α-synuclein hereditary mutation E46K unlocks a more stable, pathogenic fibril structure. | Proc Natl Acad Sci U S A | 2020 |
| 33100054 | Amyloid nomenclature 2020: update and recommendations by the International Society of Amyloidosis (ISA) nomenclature committee. | Amyloid | 2020 |
| 32632432 | Half a century of amyloids: past, present and future. | Chem Soc Rev | 2020 |
| 32796831 | CryoEM structure of the low-complexity domain of hnRNPA2 and its conversion to pathogenic amyloid. | Nat Commun | 2020 |
| 32284600 | Cryo-EM structure of a human prion fibril with a hydrophobic, protease-resistant core. | Nat Struct Mol Biol | 2020 |
| 32493775 | Crystal structure of a conformational antibody that binds tau oligomers and inhibits pathological seeding by extracts from donors with Alzheimer's disease. | J Biol Chem | 2020 |
| 30419243 | Structural Variability of EspG Chaperones from Mycobacterial ESX-1, ESX-3, and ESX-5 Type VII Secretion Systems. | J Mol Biol | 2019 |
| 31695184 | Structures of fibrils formed by α-synuclein hereditary disease mutant H50Q reveal new polymorphs. | Nat Struct Mol Biol | 2019 |
| 31748568 | Mechanically rigid supramolecular assemblies formed from an Fmoc-guanine conjugated peptide nucleic acid. | Nat Commun | 2019 |
| 31742246 | Non-proteinaceous hydrolase comprised of a phenylalanine metallo-supramolecular amyloid-like structure. | Nat Catal | 2019 |
| 31530939 | Author Correction: Atomic structures of TDP-43 LCD segments and insights into reversible or pathogenic aggregation. | Nat Struct Mol Biol | 2019 |
| 31612856 | Structure-based inhibitors of amyloid beta core suggest a common interface with tau. | Elife | 2019 |
| 31350392 | Structure of amyloid-β (20-34) with Alzheimer's-associated isomerization at Asp23 reveals a distinct protofilament interface. | Nat Commun | 2019 |
| 31235914 | Cryo-EM structures of four polymorphic TDP-43 amyloid cores. | Nat Struct Mol Biol | 2019 |
| 31537646 | Structure-based inhibitors halt prion-like seeding by Alzheimer's disease-and tauopathy-derived brain tissue samples. | J Biol Chem | 2019 |
| 30886570 | Structure-Based Peptide Inhibitor Design of Amyloid-β Aggregation. | Front Mol Neurosci | 2019 |
| 30733338 | A pair of peptides inhibits seeding of the hormone transporter transthyretin into amyloid fibrils. | J Biol Chem | 2019 |
| 29237120 | Ultrafast Time-Resolved Studies on Fluorescein for Recognition Strands Architecture in Amyloid Fibrils. | J Phys Chem B | 2018 |
| 30190461 | Cryo-EM of full-length α-synuclein reveals fibril polymorphs with a common structural kernel. | Nat Commun | 2018 |
| 30213731 | Assessment of the effects of transthyretin peptide inhibitors in Drosophila models of neuropathic ATTR. | Neurobiol Dis | 2018 |
| 30076408 | Atomic insights into the genesis of cellular filaments by globular proteins. | Nat Struct Mol Biol | 2018 |
| 30049866 | Paul D. Boyer (1918-2018). | Science | 2018 |
| 29954863 | Amyloid seeding of transthyretin by ex vivo cardiac fibrils and its inhibition. | Proc Natl Acad Sci U S A | 2018 |
| 30464263 | TDP-43 and RNA form amyloid-like myo-granules in regenerating muscle. | Nature | 2018 |
| 30297750 | Inhibiting amyloid-β cytotoxicity through its interaction with the cell surface receptor LilrB2 by structure-based design. | Nat Chem | 2018 |
| 30420778 | Author Correction: Inhibiting amyloid-β cytotoxicity through its interaction with the cell surface receptor LilrB2 by structure-based design. | Nat Chem | 2018 |