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Author Details

George P Tegos
Drexel University College of Medicine
2002
80
44
PMIDPaper TitleJournal TitlePublished Year
36715588Visible-Light-Activated Molecular Machines Kill Fungi by Necrosis Following Mitochondrial Dysfunction and Calcium Overload.Adv Sci (Weinh)2023
35574602Probiotics: insights and new opportunities for <i>Clostridioides difficile</i> intervention.Crit Rev Microbiol2023
36002317Hemithioindigo-Based Visible Light-Activated Molecular Machines Kill Bacteria by Oxidative Damage.Adv Sci (Weinh)2022
35648847Light-activated molecular machines are fast-acting broad-spectrum antibacterials that target the membrane.Sci Adv2022
32470603Early network properties of the COVID-19 pandemic - The Chinese scenario.Int J Infect Dis2020
32855026Light-based technologies for management of COVID-19 pandemic crisis.J Photochem Photobiol B2020
32653070The value of antimicrobial peptides in the age of resistance.Lancet Infect Dis2020
31249569Assessing the Dynamics and Complexity of Disease Pathogenicity Using 4-Dimensional Immunological Data.Front Immunol2019
29177837High-Throughput Flow Cytometry Screening of Multidrug Efflux Systems.Methods Mol Biol2018
29618576Options and Limitations in Clinical Investigation of Bacterial Biofilms.Clin Microbiol Rev2018
29519734Attaching NorA efflux pump inhibitors to methylene blue enhances antimicrobial photodynamic inactivation of Escherichia coli and Acinetobacter baumannii in vitro and in vivo.Bioorg Med Chem Lett2018
27884621Photoantimicrobials-are we afraid of the light?Lancet Infect Dis2017
28799332Attaching the NorA Efflux Pump Inhibitor INF55 to Methylene Blue Enhances Antimicrobial Photodynamic Inactivation of Methicillin-Resistant Staphylococcus aureus in Vitro and in Vivo.ACS Infect Dis2017
26946404Terms of endearment: Bacteria meet graphene nanosurfaces.Biomaterials2016
27734016Pneumonia and Pleural Empyema due to a Mixed <i>Lactobacillus</i> spp. Infection as a Possible Early Esophageal Carcinoma Signature.Front Med (Lausanne)2016
27411058Preventing Data Ambiguity in Infectious Diseases with Four-Dimensional and Personalized Evaluations.PLoS One2016
27375617Detecting the Hidden Properties of Immunological Data and Predicting the Mortality Risks of Infectious Syndromes.Front Immunol2016
25745401Defining the microbial effluxome in the content of the host-microbiome interaction.Front Pharmacol2015
26587842Investigating the Role of the Host Multidrug Resistance Associated Protein Transporter Family in Burkholderia cepacia Complex Pathogenicity Using a Caenorhabditis elegans Infection Model.PLoS One2015
25760340Therapeutic options and emerging alternatives for multidrug resistant staphylococcal infections.Curr Pharm Des2015
25760339Harnessing the power of light to treat staphylococcal infections focusing on MRSA.Curr Pharm Des2015
25760333Versatile approaches to target staphylococcal infections.Curr Pharm Des2015
24410618Clostridium difficile infection: molecular pathogenesis and novel therapeutics.Expert Rev Anti Infect Ther2014
25027381A high throughput flow cytometric assay platform targeting transporter inhibition.Drug Discov Today Technol2014
22923785A selective ATP-binding cassette subfamily G member 2 efflux inhibitor revealed via high-throughput flow cytometry.J Biomol Screen2013
24083556Selective photoinactivation of Candida albicans in the non-vertebrate host infection model Galleria mellonella.BMC Microbiol2013
24241242Biodefense: trends and challenges in combating biological warfare agents.Virulence2013
23890825Emerging trends in the discovery of natural product antibacterials.Curr Opin Pharmacol2013
23879608Photodynamic inactivation of biofilm: taking a lightly colored approach to stubborn infection.Expert Rev Anti Infect Ther2013
24012294Disruptive innovations: new anti-infectives in the age of resistance.Curr Opin Pharmacol2013
23802986Antimicrobial strategies centered around reactive oxygen species--bactericidal antibiotics, photodynamic therapy, and beyond.FEMS Microbiol Rev2013
23792964Efficient purification and reconstitution of ATP binding cassette transporter B6 (ABCB6) for functional and structural studies.J Biol Chem2013
23470221Fluorescent substrates for flow cytometric evaluation of efflux inhibition in ABCB1, ABCC1, and ABCG2 transporters.Anal Biochem2013
23457486Photodynamic and antibiotic therapy impair the pathogenesis of Enterococcus faecium in a whole animal insect model.PLoS One2013
23569468Microbial efflux systems and inhibitors: approaches to drug discovery and the challenge of clinical implementation.Open Microbiol J2013
23262998Blue light rescues mice from potentially fatal Pseudomonas aeruginosa burn infection: efficacy, safety, and mechanism of action.Antimicrob Agents Chemother2013
23349872Effect of virulence factors on the photodynamic inactivation of Cryptococcus neoformans.PLoS One2013
23129051Antimicrobial photodynamic inactivation inhibits Candida albicans virulence factors and reduces in vivo pathogenicity.Antimicrob Agents Chemother2013
22038048Down-regulation of glutatione S-transferase α 4 (hGSTA4) in the muscle of thermally injured patients is indicative of susceptibility to bacterial infection.FASEB J2012
22808084A novel flow cytometric HTS assay reveals functional modulators of ATP binding cassette transporter ABCB6.PLoS One2012
22846406Blue light for infectious diseases: Propionibacterium acnes, Helicobacter pylori, and beyond?Drug Resist Updat2012
22929495Ultraviolet C light for Acinetobacter baumannii wound infections in mice: potential use for battlefield wound decontamination?J Trauma Acute Care Surg2012
22514547Concepts and principles of photodynamic therapy as an alternative antifungal discovery platform.Front Microbiol2012
22546904Dissecting novel virulent determinants in the Burkholderia cepacia complex.Virulence2012
22242675Strategies to potentiate antimicrobial photoinactivation by overcoming resistant phenotypes.Photochem Photobiol2012
21073470Ultraviolet-C irradiation for prevention of central venous catheter-related infections: an in vitro study.Photochem Photobiol2011
21971183All you need is light: antimicrobial photoinactivation as an evolving and emerging discovery strategy against infectious disease.Virulence2011
21930868Blue dye and red light, a dynamic combination for prophylaxis and treatment of cutaneous Candida albicans infections in mice.Antimicrob Agents Chemother2011
21525022Influence of multidrug efflux systems on methylene blue-mediated photodynamic inactivation of Candida albicans.J Antimicrob Chemother2011
21743839Antimicrobial Photodynamic Therapy with Functionalized Fullerenes: Quantitative Structure-activity Relationships.J Nanomed Nanotechnol2011
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Collaborators

Laser Research Centre, University of Johannesburg
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Massachusetts General Hospital, Harvard Medical School
Co-authored papers 19
University of New Mexico School of Medicine
Co-authored papers 9
GAMA Therapeutics LLC
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Co-authored papers 7
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Expert Systems Inc.
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Scientific and Commercial Ltd.
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Nove de Julho UniversityUNINOVE
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ABC Federal University (UFABC)
Co-authored papers 3
Institut Quimic de Sarria, Universitat Ramon Llull
Co-authored papers 2
Massachusetts General Hospital
Co-authored papers 2
Stanford University
Co-authored papers 2
Seattle Children's Hospital, University of Washington
Co-authored papers 2
University of British Columbia
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Stanford University
Co-authored papers 1
GAMA Therapeutics LLC, USA Department of Chemistry Rice University
Co-authored papers 1
Macquarie University
Co-authored papers 1
Interdisciplinary Research Center HALOmem, Martin Luther University Halle-Wittenberg
Co-authored papers 1
University of Aveiro, Campus Universitario de Santiago
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Harvard Medical School, USA Infectious Disease Institute (P.J.M.B.
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Institute of Chemistry, University of Sao Paulo
Co-authored papers 1
Paris Lodron University of Salzburg
Co-authored papers 1
Bijvoet Center for Biomolecular Research, Utrecht University
Co-authored papers 1
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Stanford University
Co-authored papers 1