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Author Details

Ying-Wooi Wan
Baylor College of Medicine
2008
65
31
PMIDPaper TitleJournal TitlePublished Year
36640327Mutations in the transcriptional regulator MeCP2 severely impact key cellular and molecular signatures of human astrocytes during maturation.Cell Rep2023
37190222MicroRNA, mRNA, and Proteomics Biomarkers and Therapeutic Targets for Improving Lung Cancer Treatment Outcomes.Cancers (Basel)2023
36982190A Comprehensive and Integrative Approach to MeCP2 Disease Transcriptomics.Int J Mol Sci2023
36976514Loss of the Maternal Effect Gene Nlrp2 Alters the Transcriptome of Ovulated Mouse Oocytes and Impacts Expression of Histone Demethylase KDM1B.Reprod Sci2023
36924764Disruption of the ATXN1-CIC complex reveals the role of additional nuclear ATXN1 interactors in spinocerebellar ataxia type 1.Neuron2023
36848184MeCP2 regulates <i>Gdf11</i>, a dosage-sensitive gene critical for neurological function.Elife2023
36577402Disruption of the ATXN1-CIC complex reveals the role of additional nuclear ATXN1 interactors in spinocerebellar ataxia type 1.Neuron2023
35196083Activation of PDGFRA signaling contributes to filamin C-related arrhythmogenic cardiomyopathy.Sci Adv2022
35442423Chemotherapy Coupled to Macrophage Inhibition Induces T-cell and B-cell Infiltration and Durable Regression in Triple-Negative Breast Cancer.Cancer Res2022
36109320Environmental oxygen affects ex vivo growth and proliferation of mesenchymal progenitors by modulating mitogen-activated protein kinase and mammalian target of rapamycin signaling.Cytotherapy2022
33658357Antisense oligonucleotide therapy in a humanized mouse model of <i>MECP2</i> duplication syndrome.Sci Transl Med2021
33878299The bone microenvironment increases phenotypic plasticity of ER<sup>+</sup> breast cancer cells.Dev Cell2021
33871358Downregulation of glial genes involved in synaptic function mitigates Huntington's disease pathogenesis.Elife2021
33709453Dual targeting of brain region-specific kinases potentiates neurological rescue in Spinocerebellar ataxia type 1.EMBO J2021
33554954Modulation of ATXN1 S776 phosphorylation reveals the importance of allele-specific targeting in SCA1.JCI Insight2021
32159514Losing Dnmt3a dependent methylation in inhibitory neurons impairs neural function by a mechanism impacting Rett syndrome.Elife2020
31917687Type I interferon response drives neuroinflammation and synapse loss in Alzheimer disease.J Clin Invest2020
32774506Early-onset colorectal cancer: A distinct entity with unique genetic features.Oncol Lett2020
32668255Meta-Analysis of the Alzheimer's Disease Human Brain Transcriptome and Functional Dissection in Mouse Models.Cell Rep2020
30664766Loss of function of NCOR1 and NCOR2 impairs memory through a novel GABAergic hypothalamus-CA3 projection.Nat Neurosci2019
31561642A Portal to Visualize Transcriptome Profiles in Mouse Models of Neurological Disorders.Genes (Basel)2019
31222187Author Correction: Loss of function of NCOR1 and NCOR2 impairs memory through a novel GABAergic hypothalamus-CA3 projection.Nat Neurosci2019
29570050Forniceal deep brain stimulation induces gene expression and splicing changes that promote neurogenesis and plasticity.Elife2018
30104565Apparent bias toward long gene misregulation in MeCP2 syndromes disappears after controlling for baseline variations.Nat Commun2018
30108137TFEB enhances astroglial uptake of extracellular tau species and reduces tau spreading.J Exp Med2018
30415998Complement C3aR Inactivation Attenuates Tau Pathology and Reverses an Immune Network Deregulated in Tauopathy Models and Alzheimer's Disease.Neuron2018
29526553ATXN1-CIC Complex Is the Primary Driver of Cerebellar Pathology in Spinocerebellar Ataxia Type 1 through a Gain-of-Function Mechanism.Neuron2018
29382756Loss of Capicua alters early T cell development and predisposes mice to T cell lymphoblastic leukemia/lymphoma.Proc Natl Acad Sci U S A2018
28637297A Role for Progesterone-Regulated sFRP4 Expression in Uterine Leiomyomas.J Clin Endocrinol Metab2017
28361706Comprehensive evaluation of RNA-seq quantification methods for linearity.BMC Bioinformatics2017
28502612MARRVEL: Integration of Human and Model Organism Genetic Resources to Facilitate Functional Annotation of the Human Genome.Am J Hum Genet2017
28288114Disruption of the ATXN1-CIC complex causes a spectrum of neurobehavioral phenotypes in mice and humans.Nat Genet2017
28902396Data Analysis Pipeline for RNA-seq Experiments: From Differential Expression to Cryptic Splicing.Curr Protoc Bioinformatics2017
27365498Loss of MeCP2 in the rat models regression, impaired sociability and transcriptional deficits of Rett syndrome.Hum Mol Genet2016
28174757Transcriptional Regulation by ATOH1 and its Target SPDEF in the Intestine.Cell Mol Gastroenterol Hepatol2016
26568634TCGA2STAT: simple TCGA data access for integrated statistical analysis in R.Bioinformatics2016
27586041XMRF: an R package to fit Markov Networks to high-throughput genetics data.BMC Syst Biol2016
28007900Extensive cryptic splicing upon loss of RBM17 and TDP43 in neurodegeneration models.Hum Mol Genet2016
27918591Transcriptomic Analysis of Mouse Cochlear Supporting Cell Maturation Reveals Large-Scale Changes in Notch Responsiveness Prior to the Onset of Hearing.PLoS One2016
25492685A genome-wide screen for copy number alterations in an adolescent pilot cohort with müllerian anomalies.Fertil Steril2015
26605526Reversal of phenotypes in MECP2 duplication mice using genetic rescue or antisense oligonucleotides.Nature2015
24105472NLRP7 affects trophoblast lineage differentiation, binds to overexpressed YY1 and alters CpG methylation.Hum Mol Genet2014
25259927A drosophila genetic resource of mutants to study mechanisms underlying human genetic diseases.Cell2014
25392692Network-based identification of biomarkers coexpressed with multiple pathways.Cancer Inform2014
25186948Serine catabolism regulates mitochondrial redox control during hypoxia.Cancer Discov2014
24463180Combinatorial therapy discovery using mixed integer linear programming.Bioinformatics2014
24489963On the reproducibility of TCGA ovarian cancer microRNA profiles.PLoS One2014
23497278Digital sorting of complex tissues for cell type-specific gene expression profiles.BMC Bioinformatics2013
24564637Molecular pathway identification using biological network-regularized logistic models.BMC Genomics2013
23690307Expression and functional pathway analysis of nuclear receptor NR2F2 in ovarian cancer.J Clin Endocrinol Metab2013
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Collaborators

Zhandong Liu
Jan and Dan Duncan Neurological Research Institute at Texas Children's Hospital
Co-authored papers 43
Genevera I Allen
Jan and Dan Duncan Neurological Research Institute at Texas Children's Hospital
Co-authored papers 5
Hui Zheng
Baylor College of Medicine
Co-authored papers 4
Rami Al-Ouran
Baylor College of Medicine
Co-authored papers 4
Nicholas E Propson
Co-authored papers 2
Tom V Lee
Baylor College of Medicine
Co-authored papers 2
John Q Trojanowski
University of Pennsylvania
Co-authored papers 2
Virginia M-Y Lee
Perelman School of Medicine at the University of Pennsylvania
Co-authored papers 2
Juan Botas
Baylor College of Medicine
Co-authored papers 2
Joshua M Shulman
Baylor College of Medicine
Co-authored papers 2
Shinya Yamamoto
Baylor College of Medicine, TX Jan and Dan Duncan Neurological Research Institute
Co-authored papers 2
Michael F Wangler
Baylor College of Medicine
Co-authored papers 2
Hugo J Bellen
Baylor College of Medicine
Co-authored papers 2
Pengfei Liu
Co-authored papers 2
Heidi Martini-Stoica
Baylor College of Medicine
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Ghayda M Mirzaa
Seattle Children's Hospital.
Co-authored papers 1
Tomasz Gambin
Institute of Computer Science, Warsaw University of Technology
Co-authored papers 1
Paramita Chakrabarty
Center for Translational Research in Neurodegenerative Disease, University of Florida
Co-authored papers 1
Nathan D Price
Institute for Systems Biology
Co-authored papers 1
Yanhui Hu
Co-authored papers 1
Yunping Lei
Center for Precision Environmental Health, Baylor College of Medicine
Co-authored papers 1
Kristen K Dang
Benaroya Research Institute at Virginia Mason
Co-authored papers 1
Allan I Levey
Emory University School of Medicine
Co-authored papers 1
Eric W Klee
Mayo Clinic College of Medicine and Science
Co-authored papers 1
Cory C Funk
Institute for Systems Biology
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David A Bennett
Rush University Medical Center
Co-authored papers 1
Sara Mostafavi
University of British Columbia and BC Children's Hospital
Co-authored papers 1
Robin D Clark
Loma Linda University Health
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