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Author Details

Sami Mahrus
Department of Pharmaceutical Chemistry, University of California san francisco
2000
21
19
Andrej Sali (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
35511917Replication of Overall Survival, Progression-Free Survival, and Overall Response in Chemotherapy Arms of Non-Small Cell Lung Cancer Trials Using Real-World Data.Clin Cancer Res2022
30770348Phase I Study of the Indoleamine 2,3-Dioxygenase 1 (IDO1) Inhibitor Navoximod (GDC-0919) Administered with PD-L1 Inhibitor (Atezolizumab) in Advanced Solid Tumors.Clin Cancer Res2019
29788155Phase I study of the checkpoint kinase 1 inhibitor GDC-0575 in combination with gemcitabine in patients with refractory solid tumors.Ann Oncol2018
30141341A validated surrogate analyte LC-MS/MS assay for quantitation of endogenous kynurenine and tryptophan in human plasma.Bioanalysis2018
29921320Phase Ia study of the indoleamine 2,3-dioxygenase 1 (IDO1) inhibitor navoximod (GDC-0919) in patients with recurrent advanced solid tumors.J Immunother Cancer2018
27815358Phase I Study of GDC-0425, a Checkpoint Kinase 1 Inhibitor, in Combination with Gemcitabine in Patients with Refractory Solid Tumors.Clin Cancer Res2017
23264352The DegraBase: a database of proteolysis in healthy and apoptotic human cells.Mol Cell Proteomics2013
22308409Global kinetic analysis of proteolysis via quantitative targeted proteomics.Proc Natl Acad Sci U S A2012
22802652Quantitative profiling of caspase-cleaved substrates reveals different drug-induced and cell-type patterns in apoptosis.Proc Natl Acad Sci U S A2012
20505003Prediction of protease substrates using sequence and structure features.Bioinformatics2010
20723762Activation of specific apoptotic caspases with an engineered small-molecule-activated protease.Cell2010
18722006Global sequencing of proteolytic cleavage sites in apoptosis by specific labeling of protein N termini.Cell2008
18762420Tags for labeling protein N-termini with subtiligase for proteomics.Bioorg Med Chem Lett2008
16895390Isotope-coded and affinity-tagged cross-linking (ICATXL): an efficient strategy to probe protein interaction surfaces.J Am Chem Soc2006
15911377Selective chemical functional probes of granzymes A and B reveal granzyme B is a major effector of natural killer cell-mediated lysis of target cells.Chem Biol2005
15494398Granzyme M is a regulatory protease that inactivates proteinase inhibitor 9, an endogenous inhibitor of granzyme B.J Biol Chem2004
12819769The oligomeric structure of human granzyme A is a determinant of its extended substrate specificity.Nat Struct Biol2003
11773410Altered substrate specificity of drug-resistant human immunodeficiency virus type 1 protease.J Virol2002
11468352Novel inter-protein cross-link identified in the GGH-ecotin D137Y dimer.Protein Sci2001
10702240Cathepsin G activates protease-activated receptor-4 in human platelets.J Biol Chem2000
10869434Rapid and general profiling of protease specificity by using combinatorial fluorogenic substrate libraries.Proc Natl Acad Sci U S A2000
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Collaborators

Charles S Craik
Department of Pharmaceutical Chemistry, University of California san francisco
Co-authored papers 9
James A Wells
Department of Pharmaceutical Chemistry, University of California San Francisco
Co-authored papers 7
Alma L Burlingame
Department of Pharmaceutical Chemistry, University of California san francisco
Co-authored papers 5
Jennifer L Harris
Co-authored papers 3
Jonathan C Trinidad
Indiana University
Co-authored papers 3
Andrej Sali (CM4AI)
University of California San Francisco
Co-authored papers 2
David T Barkan
Novartis Institutes for BioMedical Research, Inc.
Co-authored papers 2
Huy Nguyen
The University of Danang-University of Science and Technology
Co-authored papers 2
Shaun R Coughlin
Co-authored papers 1
Kari M Morrissey
Amunix Pharmaceuticals
Co-authored papers 1
Gregory J Riely
Memorial Sloan Kettering Cancer Center
Co-authored papers 1
Sara M Tolaney
Dana-Farber Cancer Institute
Co-authored papers 1
Maria D Person
Center for Biomedical Research Support, The University of Texas at Austin
Co-authored papers 1
Feixia Chu
University of New Hampshire
Co-authored papers 1
Robert J Fletterick
University of California San Francisco
Co-authored papers 1
Emily D Crawford
Co-authored papers 1
Gilberto R Sambrano
Co-authored papers 1
Robert J Chalkley
Department of Pharmaceutical Chemistry, University of California at San Francisco
Co-authored papers 1
Ursula Pieper
University of California san francisco
Co-authored papers 1
Release 1.2