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Author Details

Jun Takahashi
Center for iPS Cell Research and Application, Kyoto University
1993
151
49
PMIDPaper TitleJournal TitlePublished Year
36566381Protocol for making an animal model of "blindsight" in macaque monkeys.STAR Protoc2023
37146578Next steps in regenerative medicine.Cell Stem Cell2023
36963389Viral delivery of L1CAM promotes axonal extensions by embryonic cerebral grafts in mouse brain.Stem Cell Reports2023
34958047Cryopreservation of Induced Pluripotent Stem Cell-Derived Dopaminergic Neurospheres for Clinical Application.J Parkinsons Dis2022
35605097Pretreatment with Perlecan-Conjugated Laminin-E8 Fragment Enhances Maturation of Grafted Dopaminergic Progenitors in Parkinson's Disease Model.Stem Cells Transl Med2022
35155722Automated measurement of fluorescence signals reveals a significant increase of the graft-derived neurite extension in neonates compared to aged rats.Regen Ther2022
33443074Contribution of the Pulvinar and Lateral Geniculate Nucleus to the Control of Visually Guided Saccades in Blindsight Monkeys.J Neurosci2021
33545076Clinical Trial for Parkinson's Disease Gets a Green Light in the US.Cell Stem Cell2021
34284947Analysis of extracellular vesicles as a potential index for monitoring differentiation of neural lineage cells from induced pluripotent stem cells.J Biosci Bioeng2021
34024783Evading the Immune System: Immune Modulation and Immune Matching in Cell Replacement Therapies for Parkinson's Disease.J Parkinsons Dis2021
34048695ISSCR guidelines for the transfer of human pluripotent stem cells and their direct derivatives into animal hosts.Stem Cell Reports2021
34048692ISSCR Guidelines for Stem Cell Research and Clinical Translation: The 2021 update.Stem Cell Reports2021
32140099L1CAM Is a Marker for Enriching Corticospinal Motor Neurons in the Developing Brain.Front Cell Neurosci2020
33490319iPS cell-based therapy for Parkinson's disease: A Kyoto trial.Regen Ther2020
31724030Induction of the germ cell fate from pluripotent stem cells in cynomolgus monkeysâ¿ .Biol Reprod2020
31929121Exercise Promotes Neurite Extensions from Grafted Dopaminergic Neurons in the Direction of the Dorsolateral Striatum in Parkinson's Disease Model Rats.J Parkinsons Dis2020
31914385Hypothalamic Contribution to Pituitary Functions Is Recapitulated In Vitro Using 3D-Cultured Human iPS Cells.Cell Rep2020
33188020Therapeutics potentiating microglial p21-Nrf2 axis can rescue neurodegeneration caused by neuroinflammation.Sci Adv2020
32632153Pre-clinical study of induced pluripotent stem cell-derived dopaminergic progenitor cells for Parkinson's disease.Nat Commun2020
32679062Axonal Extensions along Corticospinal Tracts from Transplanted Human Cerebral Organoids.Stem Cell Reports2020
32978383Versatile live-cell activity analysis platform for characterization of neuronal dynamics at single-cell and network level.Nat Commun2020
32506530Zonisamide promotes survival of human-induced pluripotent stem cell-derived dopaminergic neurons in the striatum of female rats.J Neurosci Res2020
30644333Preparing for first human trial of induced pluripotent stem cell-derived cells for Parkinson's disease: an interview with Jun Takahashi.Regen Med2019
31708734MicroRNA-Based Separation of Cortico-Fugal Projection Neuron-Like Cells Derived From Embryonic Stem Cells.Front Neurosci2019
31231547Therapeutic effects of combined cell transplantation and locomotor training in rats with brain injury.NPJ Regen Med2019
31257131Self-Organized Synchronous Calcium Transients in a Cultured Human Neural Network Derived from Cerebral Organoids.Stem Cell Reports2019
31509736The Ethics of Cerebral Organoid Research: Being Conscious of Consciousness.Stem Cell Reports2019
30891830Xeno-free culture for generation of forebrain oligodendrocyte precursor cells from human pluripotent stem cells.J Neurosci Res2019
30846821Verification and rectification of cell type-specific splicing of a Seckel syndrome-associated ATR mutation using iPS cell model.J Hum Genet2019
29110329Transplantation of feeder-free human induced pluripotent stem cell-derived cortical neuron progenitors in adult male Wistar rats with focal brain ischemia.J Neurosci Res2018
30061169Three-dimensional induction of dorsal, intermediate and ventral spinal cord tissues from human pluripotent stem cells.Development2018
29742388The Challenges of First-in-Human Stem Cell Clinical Trials: What Does This Mean for Ethics and Institutional Review Boards?Stem Cell Reports2018
29713910Employment status and termination among survivors of pediatric brain tumors: a cross-sectional survey.Int J Clin Oncol2018
29621691Stem cells and regenerative medicine for neural repair.Curr Opin Biotechnol2018
28552230Strategies for bringing stem cell-derived dopamine neurons to the clinic: The Kyoto trial.Prog Brain Res2017
30566308Cell-based therapies for Parkinson's disease.Nihon Rinsho2017
28233934Idiopathic Parkinson's disease patient-derived induced pluripotent stem cells function as midbrain dopaminergic neurons in rodent brains.J Neurosci Res2017
29100010Human Trials of Stem Cell-Derived Dopamine Neurons for Parkinson's Disease: Dawn of a New Era.Cell Stem Cell2017
28858313Human iPS cell-derived dopaminergic neurons function in a primate Parkinson's disease model.Nature2017
28855509MHC matching improves engraftment of iPSC-derived neurons in non-human primates.Nat Commun2017
28507510Enhanced Axonal Extension of Subcortical Projection Neurons Isolated from Murine Embryonic Cortex using Neuropilin-1.Front Cell Neurosci2017
26997644Estradiol Facilitates Functional Integration of iPSC-Derived Dopaminergic Neurons into Striatal Neuronal Circuits via Activation of Integrin α5β1.Stem Cell Reports2016
27739432Purification of functional human ES and iPSC-derived midbrain dopaminergic progenitors using LRTM1.Nat Commun2016
27608814MicroRNA-302 switch to identify and eliminate undifferentiated human pluripotent stem cells.Sci Rep2016
27599427iPS cell therapy for Parkinson's disease.Rinsho Ketsueki2016
27798097Genetic and pharmacological correction of aberrant dopamine synthesis using patient iPSCs with BH4 metabolism disorders.Hum Mol Genet2016
27346608Cytoplasmic aggregates of dynactin in iPSC-derived tyrosine hydroxylase-positive neurons from a patient with Perry syndrome.Parkinsonism Relat Disord2016
27181719[Cell therapy for Parkinson's disease].Nihon Yakurigaku Zasshi2016
26941358WNT-C59, a Small-Molecule WNT Inhibitor, Efficiently Induces Anterior Cortex That Includes Cortical Motor Neurons From Human Pluripotent Stem Cells.Stem Cells Transl Med2016
26912295Cell Therapy for Parkinson's Disease.Neurol Med Chir (Tokyo)2016
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Saitama Medical University International Medical Center
Co-authored papers 5
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John Van Geest Center for Brain Repair, University of Cambridge
Co-authored papers 4
Misao Fujita
Institute for the Advanced Study of Human Biology (WPI-ASHBi), Kyoto University
Co-authored papers 3
Masayo Takahashi
Kobe City Eye Hospital
Co-authored papers 3
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Kitasato University School of Medicine
Co-authored papers 3
Kiyotoshi Sekiguchi
Co-authored papers 3
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Center for Translational Neuromedicine, University of Rochester Medical Center
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Institute of Molecular Biotechnology of the Austrian Academy of Sciences (IMBA)
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The Center for Stem Cell Biology, Memorial Sloan Kettering Cancer Center
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Stanford University
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Mitinori Saitou
Institute for the Advanced Study of Human Biology (ASHBi), Kyoto University
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Hiromitsu Nakauchi
Advanced Research Institute, Tokyo Medical and Dental University
Co-authored papers 2
Yali Cong
Department of Medical Ethics and Law, Peking University Health Science Center
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E Clayton
Harvard Medical School, Vanderbilt University, Yale University Yale Law School
Co-authored papers 2
Insoo Hyun
Center for Bioethics, Harvard Medical School
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Robin Lovell-Badge
The Francis Crick Institute
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Ali H Brivanlou
the Rockefeller University
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Jeffrey P Kahn
Berman Institute of Bioethics, Johns Hopkins University
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Osaka University
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Release 1.2