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Author Details

Donald J Zack
Johns Hopkins University School of Medicine
1980
298
78
PMIDPaper TitleJournal TitlePublished Year
38082180Screening for lipid nanoparticles that modulate the immune activity of helper T cells towards enhanced antitumour activity.Nat Biomed Eng2024
36680758Traumatic Axonal Injury in the Optic Nerve: The Selective Role of SARM1 in the Evolution of Distal Axonopathy.J Neurotrauma2023
38025164The Retinal Ganglion Cell Repopulation, Stem Cell Transplantation, and Optic Nerve Regeneration Consortium.Ophthalmol Sci2023
37802075Rare intercellular material transfer as a confound to interpreting inner retinal neuronal transplantation following internal limiting membrane disruption.Stem Cell Reports2023
37904133Neutral sphingomyelinase inhibition promotes local and network degeneration in vitro and in vivo.Cell Commun Signal2023
37849975Deciphering viscoelastic cell manipulation in rectangular microchannels.Phys Fluids (1994)2023
37657693Engineered peptide-drug conjugate provides sustained protection of retinal ganglion cells with topical administration in rats.J Control Release2023
38062868A Novel Approach to Increase Glial Cell Populations in Brain Microphysiological Systems.Adv Biol (Weinh)2023
37745321A novel approach to increase glial cell populations in brain microphysiological systems.bioRxiv2023
37645816Intercellular communication atlas reveals Oprm1 as a neuroprotective factor for retinal ganglion cells.Res Sq2023
37502873Intercellular communication atlas reveals Oprm1 as a neuroprotective factor for retinal ganglion cells.bioRxiv2023
37762022Regional Gene Expression in the Retina, Optic Nerve Head, and Optic Nerve of Mice with Optic Nerve Crush and Experimental Glaucoma.Int J Mol Sci2023
37190063IKKβ Inhibition Attenuates Epithelial Mesenchymal Transition of Human Stem Cell-Derived Retinal Pigment Epithelium.Cells2023
36993314Regional Gene Expression in the Retina, Optic Nerve Head, and Optic Nerve of Mice with Experimental Glaucoma and Optic Nerve Crush.bioRxiv2023
37010860Microfluidic Platforms Promote Polarization of Human-Derived Retinal Ganglion Cells That Model Axonopathy.Transl Vis Sci Technol2023
37009209The importance of unambiguous cell origin determination in neuronal repopulation studies.iScience2023
36925616First Organoid Intelligence (OI) workshop to form an OI community.Front Artif Intell2023
36690463Alternative RNA Splicing in the Retina: Insights and Perspectives.Cold Spring Harb Perspect Med2023
34985952High-throughput and high-content bioassay enables tuning of polyester nanoparticles for cellular uptake, endosomal escape, and systemic in vivo delivery of mRNA.Sci Adv2022
35709078Aquaporin 4 is not present in normal porcine and human lamina cribrosa.PLoS One2022
35584680Human photoreceptors switch from autonomous axon extension to cell-mediated process pulling during synaptic marker redistribution.Cell Rep2022
35802384Integrated Stress Response Regulation of Corneal Epithelial Cell Motility and Cytokine Production.Invest Ophthalmol Vis Sci2022
35764123Differential expression patterns of phospholipase D isoforms 1 and 2 in the mammalian brain and retina.J Lipid Res2022
35600072Reactive Astrocytes Derived From Human Induced Pluripotent Stem Cells Suppress Oligodendrocyte Precursor Cell Differentiation.Front Mol Neurosci2022
35394873Monocyte-derived SDF1 supports optic nerve regeneration and alters retinal ganglion cells' response to Pten deletion.Proc Natl Acad Sci U S A2022
35812361Restoring partial vision to a blind patient.Fac Rev2022
36423582Quantitative fate mapping: A general framework for analyzing progenitor state dynamics via retrospective lineage barcoding.Cell2022
36030648Fatality assessment and variant risk monitoring for COVID-19 using three new hospital occupancy related metrics.EBioMedicine2022
36291110Ex Vivo Integration of Human Stem Retinal Ganglion Cells into the Mouse Retina.Cells2022
33900546A hypotonic gel-forming eye drop provides enhanced intraocular delivery of a kinase inhibitor with melanin-binding properties for sustained protection of retinal ganglion cells.Drug Deliv Transl Res2022
35095414Temporal and Isoform-Specific Expression of <i>CTBP2</i> Is Evolutionarily Conserved Between the Developing Chick and Human Retina.Front Mol Neurosci2022
33382979Role of the Internal Limiting Membrane in Structural Engraftment and Topographic Spacing of Transplanted Human Stem Cell-Derived Retinal Ganglion Cells.Stem Cell Reports2021
33792620Transcriptome Landscape of Epithelial to Mesenchymal Transition of Human Stem Cell-Derived RPE.Invest Ophthalmol Vis Sci2021
33510160Single-cell transcriptomic reveals molecular diversity and developmental heterogeneity of human stem cell-derived oligodendrocyte lineage cells.Nat Commun2021
34869356CRISPR Generated SIX6 and POU4F2 Reporters Allow Identification of Brain and Optic Transcriptional Differences in Human PSC-Derived Organoids.Front Cell Dev Biol2021
34383881Intrinsic Morphologic and Physiologic Development of Human Derived Retinal Ganglion Cells In Vitro.Transl Vis Sci Technol2021
34487221Complement component 3 from astrocytes mediates retinal ganglion cell loss during neuroinflammation.Acta Neuropathol2021
34455105Proteome Landscape of Epithelial-to-Mesenchymal Transition (EMT) of Retinal Pigment Epithelium Shares Commonalities With Malignancy-Associated EMT.Mol Cell Proteomics2021
34686321Proteomic and phosphoproteomic analyses identify liver-related signaling in retinal pigment epithelial cells during EMT.Cell Rep2021
34184634Large-scale phenotypic drug screen identifies neuroprotectants in zebrafish and mouse models of retinitis pigmentosa.Elife2021
34062883Ion-Complex Microcrystal Formulation Provides Sustained Delivery of a Multimodal Kinase Inhibitor from the Subconjunctival Space for Protection of Retinal Ganglion Cells.Pharmaceutics2021
33951368We Shall See?N Engl J Med2021
34228937Size-Controlled and Shelf-Stable DNA Particles for Production of Lentiviral Vectors.Nano Lett2021
33404293BNIP3L-mediated mitophagy is required for mitochondrial remodeling during the differentiation of optic nerve oligodendrocytes.Autophagy2021
32386599Single-Cell Analysis of Human Retina Identifies Evolutionarily Conserved and Species-Specific Mechanisms Controlling Development.Dev Cell2020
32031578TNFα-Mediated Priming of Mesenchymal Stem Cells Enhances Their Neuroprotective Effect on Retinal Ganglion Cells.Invest Ophthalmol Vis Sci2020
32081919Investigating cone photoreceptor development using patient-derived NRL null retinal organoids.Commun Biol2020
33318207Inhibition of GCK-IV kinases dissociates cell death and axon regeneration in CNS neurons.Proc Natl Acad Sci U S A2020
32936736Human Organoids for the Study of Retinal Development and Disease.Annu Rev Vis Sci2020
32895514Gelling hypotonic polymer solution for extended topical drug delivery to the eye.Nat Biomed Eng2020
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Collaborators

The Wilmer Eye Institute, Johns Hopkins University School of Medicine
Co-authored papers 58
Co-authored papers 35
College of Animal Science and Technology, Guangxi University
Co-authored papers 25
National Eye Institute, National Institutes of Health
Co-authored papers 21
Cleveland Institute for Computational Biology, Case Western Reserve University
Co-authored papers 21
Co-authored papers 20
Icahn School of Medicine at Mount Sinai
Co-authored papers 17
Shiley Eye Institute, University of California San Diego
Co-authored papers 17
NYU Grossman School of Medicine
Co-authored papers 16
Augusta University
Co-authored papers 16
NYU College of Arts and Sciences
Co-authored papers 16
Scripps Institution of Oceanography, University of California San Diego
Co-authored papers 15
Marshfield Clinic Research Institute
Co-authored papers 13
John P. Hussman Institute for Human Genomics.
Co-authored papers 13
Co-authored papers 13
Northwestern University
Co-authored papers 12
Genentech Inc.
Co-authored papers 12
Harvard T. H. Chan School of Public Health
Co-authored papers 11
Shiley Eye Institute, University of California
Co-authored papers 9
Center for Human Disease Modeling, Duke University School of Medicine
Co-authored papers 8
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Johns Hopkins School of Medicine
Co-authored papers 8
Harvard University
Co-authored papers 8
University of Minnesota Medical School, 1035 University Drive duluth
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Johns Hopkins University School of Medicine.
Co-authored papers 7
Einhorn Clinical Research Center, New York Eye and Ear Infirmary of Mount Sinai
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Scheie Eye Institute, Perelman School of Medicine, University of Pennsylvania
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Columbia University Medical Center
Co-authored papers 7
University of Massachusetts Chan Medical School
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Columbia University
Co-authored papers 6