Author details

Full Name

Thomas Lemmin

Affiliation

ORCID

Career Start Year

2010

Papers

H Index

Expertise

CM4AI Collaborator

PMID	Paper Title	Journal Title	Published Year
36716368	Structure and supramolecular organization of the canine distemper virus attachment glycoprotein.		2023
37605043	Trapping the HIV-1 V3 loop in a helical conformation enables broad neutralization.	Nat Struct Mol Biol	2023
36310334	Structure of the human heterodimeric transporter 4F2hc-LAT2 in complex with Anticalin, an alternative binding protein for applications in single-particle cryo-EM.	Scientific Reports	2022
34904568	Allosteric mechanism of signal transduction in the two-component system histidine kinase PhoQ.	Elife	2021
34226545	Cryo-EM structure and dynamics of the green-light absorbing proteorhodopsin.	Nature Communications	2021
34795280	Distinct conformations of the HIV-1 V3 loop crown are targetable for broad neutralization.	Nat Commun	2021
34461897	High-resolution structure of the amino acid transporter AdiC reveals insights into the role of water molecules and networks in oligomerization and substrate binding.	BMC Biology	2021
33043289	Structures and dynamics of the novel S1/S2 protease cleavage site loop of the SARS-CoV-2 spike glycoprotein.	Journal of Structural Biology: X	2020
32392050	RosENet: Improving Binding Affinity Prediction by Leveraging Molecular Mechanics Energies with an Ensemble of 3D Convolutional Neural Networks.	Journal of Chemical Information and Modeling	2020
31640540	Glycosylator: a Python framework for the rapid modeling of glycans.	BMC Bioinformatics	2019
29771498	Structure and Function of the Transmembrane Domain of NsaS, an Antibiotic Sensing Histidine Kinase in Staphylococcus aureus.	J Am Chem Soc	2018
29867235	Epitope-based vaccine design yields fusion peptide-directed antibodies that neutralize diverse strains of HIV-1.	Nat Med	2018
29311311	Structural heterogeneity and intersubject variability of AÎ² in familial and sporadic Alzheimer's disease.	Proc Natl Acad Sci U S A	2018
28133812	Antibodyomics: bioinformatics technologies for understanding B-cell immunity to HIV-1.	Immunol Rev	2017
28890362	Microsecond Dynamics and Network Analysis of the HIV-1 SOSIP Env Trimer Reveal Collective Behavior and Conserved Microdomains of the Glycan Shield.	Structure	2017
28445724	Quantification of the Impact of the HIV-1-Glycan Shield on Antibody Elicitation.	Cell Rep	2017
28973862	De novo design of covalently constrained mesosize protein scaffolds with unique tertiary structures.	Proc Natl Acad Sci U S A	2017
28837163	A 31-residue peptide induces aggregation of tau's microtubule-binding region in cells.	Nat Chem	2017
28835537	XFEL structures of the influenza M2 proton channel: Room temperature water networks and insights into proton conduction.	Proc Natl Acad Sci U S A	2017
29168496	De novo design of a hyperstable non-natural protein-ligand complex with sub-Ã¿ accuracy.	Nat Chem	2017
28166380	Insights from NMR Spectroscopy into the Conformational Properties of Man-9 and Its Recognition by Two HIV Binding Proteins.	ChemBioChem	2017
27725984	Infrared and fluorescence assessment of the hydration status of the tryptophan gate in the influenza A M2 proton channel.	Phys Chem Chem Phys	2016
27114034	Trimeric HIV-1-Env Structures Define Glycan Shields from Clades A, B, and G.	Cell	2016
27414264	Structural Polymorphism of Alzheimer's Î²-Amyloid Fibrils as Controlled by an E22 Switch: A Solid-State NMR Study.	J Am Chem Soc	2016
27174988	Fusion peptide of HIV-1 as a site of vulnerability to neutralizing antibody.	Science	2016
27001731	Designed metalloprotein stabilizes a semiquinone radical.	Nat Chem	2016
26689967	Structures of HIV-1 Env V1V2 with broadly neutralizing antibodies reveal commonalities that enable vaccine design.	Nat Struct Mol Biol	2016
27518597	Effect of the Synaptic Plasma Membrane on the Stability of the Amyloid Precursor Protein Homodimer.	J Phys Chem Lett	2016
26172072	A coiled coil switch mediates cold sensing by the thermosensory protein DesK.	Mol Microbiol	2015
26606666	LipidBuilder: A Framework To Build Realistic Models for Biological Membranes.	J Chem Inf Model	2015
24706822	Critical roles of isoleucine-364 and adjacent residues in a hydrophobic gate control of phospholipid transport by the mammalian P4-ATPase ATP8A2.	Proc Natl Acad Sci U S A	2014
24469457	Perturbations of the straight transmembrane Î±-helical structure of the amyloid precursor protein affect its processing by Î³-secretase.	J Biol Chem	2014
24914486	Reaction Mechanism and Catalytic Fingerprint of Allantoin Racemase.	J Phys Chem B	2014
23554269	In-depth analysis of hyaline fibromatosis syndrome frameshift mutations at the same site reveal the necessity of personalized therapy.	Hum Mutat	2013
26589063	Cardiolipin Models for Molecular Simulations of Bacterial and Mitochondrial Membranes.	J Chem Theory Comput	2013
23907250	Alzheimer's disease mutations in APP but not Î³-secretase modulators affect epsilon-cleavage-dependent AICD production.	Nat Commun	2013
23359663	Assembly of the transmembrane domain of E. coli PhoQ histidine kinase: implications for signal transduction from molecular simulations.	PLoS Comput Biol	2013
22314232	Palmitoylated calnexin is a key component of the ribosome-translocon complex.	EMBO J	2012
20654648	Model-based attenuation of movement artifacts in fMRI.	Journal of Neuroscience Methods	2010