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Author Details

Lindsay A Farrer
Boston University Chobanian & Avedisian School of Medicine
1984
487
97
Trey Ideker (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
37984853Sex-specific genetic architecture of late-life memory performance.Alzheimers Dement2024
37578203DNA from multiple viral species is associated with Alzheimer's disease risk.Alzheimers Dement2024
37985223Longitudinal change in memory performance as a strong endophenotype for Alzheimer's disease.Alzheimers Dement2024
35319157Midlife lipid and glucose levels are associated with Alzheimer's disease.Alzheimers Dement2023
37629231Genetics of Alzheimer's Disease in the African American Population.J Clin Med2023
37745545Structural Variation Detection and Association Analysis of Whole-Genome-Sequence Data from 16,905 Alzheimer's Diseases Sequencing Project Subjects.medRxiv2023
37841863The impact of blood MCP-1 levels on Alzheimer's disease with genetic variation of UNC5C and NAV3 loci.Res Sq2023
37693582Extended genome-wide association study employing the African Genome Resources Panel identifies novel susceptibility loci for Alzheimer's Disease in individuals of African ancestry.medRxiv2023
37693521Association of Common and Rare Variants with Alzheimer's Disease in over 13,000 Diverse Individuals with Whole-Genome Sequencing from the Alzheimer's Disease Sequencing Project.medRxiv2023
37930705APOE Genotype and Alzheimer Disease Risk Across Age, Sex, and Population Ancestry.JAMA Neurol2023
37459083Associations of Sex, Race, and Apolipoprotein E Alleles With Multiple Domains of Cognition Among Older Adults.JAMA Neurol2023
37388919A systems biology approach uncovers novel disease mechanisms in age-related macular degeneration.Cell Genom2023
37349795A genome-wide search for pleiotropy in more than 100,000 harmonized longitudinal cognitive domain scores.Mol Neurodegener2023
37051669A haptoglobin (HP) structural variant alters the effect of APOE alleles on Alzheimer's disease.Alzheimers Dement2023
37260021Novel loci for Alzheimer's disease identified by a genome-wide association study in Ashkenazi Jews.Alzheimers Dement2023
37461624Multi-ancestry genome-wide meta-analysis of 56,241 individuals identifies <i>LRRC4C, LHX5-AS1</i> and nominates ancestry-specific loci <i>PTPRK</i> , <i>GRB14</i> , and <i>KIAA0825</i> as novel risk loci for Alzheimer's disease: the Alzheimer's Disease Genetics Consortium.medRxiv2023
36543923African ancestry GWAS of dementia in a large military cohort identifies significant risk loci.Mol Psychiatry2023
36809323Association of African Ancestry-Specific APOE Missense Variant R145C With Risk of Alzheimer Disease.JAMA2023
36396603Blood levels of MCP-1 modulate the genetic risks of Alzheimer's disease mediated by HLA-DRB1 and APOE for Alzheimer's disease.Alzheimers Dement2023
36711847Circulating Endothelial Progenitor Cells Reduce the Risk of Alzheimer's Disease.medRxiv2023
36642501Heritability of cognitive abilities and regional brain structures in middle-aged to elderly East Asians.Cereb Cortex2023
36539198Admixture mapping identifies novel Alzheimer's disease risk regions in African Americans.Alzheimers Dement2023
36705426Pleiotropy analysis between lobar intracerebral hemorrhage and CSF β-amyloid highlights new and established associations.Int J Stroke2023
36795937Identification of circRNAs linked to Alzheimer's disease and related dementias.Alzheimers Dement2023
34152079Association of mitochondrial variants and haplogroups identified by whole exome sequencing with Alzheimer's disease.Alzheimers Dement2022
35587224Molecular Quantitative Trait Locus Mapping in Human Complex Diseases.Curr Protoc2022
35770850Genome-wide association and multi-omics studies identify MGMT as a novel risk gene for Alzheimer's disease among women.Alzheimers Dement2022
35379992New insights into the genetic etiology of Alzheimer's disease and related dementias.Nat Genet2022
35759276Association of APOE Genotypes and Chronic Traumatic Encephalopathy.JAMA Neurol2022
35567427Alzheimer's disease associated AKAP9 I2558M mutation alters posttranslational modification and interactome of tau and cellular functions in CRISPR-edited human neuronal cells.Aging Cell2022
35552371Sex differences in the genetic architecture of cognitive resilience to Alzheimer's disease.Brain2022
36550123The impact of increasing levels of blood C-reactive protein on the inflammatory loci SPI1 and CD33 in Alzheimer's disease.Transl Psychiatry2022
36614910Genome-Wide Pleiotropy Study Identifies Association of <i>PDGFB</i> with Age-Related Macular Degeneration and COVID-19 Infection Outcomes.J Clin Med2022
36411364Exome sequencing identifies rare damaging variants in ATP8B4 and ABCA1 as risk factors for Alzheimer's disease.Nat Genet2022
36105871Different loneliness types, cognitive function, and brain structure in midlife: Findings from the Framingham Heart Study.EClinicalMedicine2022
35258170Progranulin mutations in clinical and neuropathological Alzheimer's disease.Alzheimers Dement2022
35156446Genome-wide association study of brain arteriolosclerosis.J Cereb Blood Flow Metab2022
35210353An association test of the spatial distribution of rare missense variants within protein structures identifies Alzheimer's disease-related patterns.Genome Res2022
35142023Protein phosphatase 2A and complement component 4 are linked to the protective effect of APOE ɿ2 for Alzheimer's disease.Alzheimers Dement2022
35139885Blood and brain transcriptome analysis reveals APOE genotype-mediated and immune-related pathways involved in Alzheimer disease.Alzheimers Res Ther2022
33243459Analysis of telomere length variation and Shelterin complex subunit gene expression changes in ethanol-exposed human embryonic stem cells.J Psychiatr Res2021
33907181Cell-type-specific expression quantitative trait loci associated with Alzheimer disease in blood and brain tissue.Transl Psychiatry2021
33804025Set-Based Rare Variant Expression Quantitative Trait Loci in Blood and Brain from Alzheimer Disease Study Participants.Genes (Basel)2021
35005195Large-scale sequencing studies expand the known genetic architecture of Alzheimer's disease.Alzheimers Dement (Amst)2021
34384490Developing methods to detect and diagnose chronic traumatic encephalopathy during life: rationale, design, and methodology for the DIAGNOSE CTE Research Project.Alzheimers Res Ther2021
34785643A missense variant in SHARPIN mediates Alzheimer's disease-specific brain damages.Transl Psychiatry2021
34601489Exploration of alcohol use disorder-associated brain miRNA-mRNA regulatory networks.Transl Psychiatry2021
34480088Integrative brain transcriptome analysis links complement component 4 and HSPA2 to the APOE ε2 protective effect in Alzheimer disease.Mol Psychiatry2021
34124712Genome-wide association study of phenotypes measuring progression from first cocaine or opioid use to dependence reveals novel risk genes.Explor Med2021
34226506Genome-wide association study of stimulant dependence.Transl Psychiatry2021
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Collaborators

Cleveland Institute for Computational Biology, Case Western Reserve University
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Cambridge Institute for Medical Research, University of Cambridge
Co-authored papers 54
Brigham and Women's Hospital, Broad Institute Ariadne Labs and Harvard Medical School
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Columbia University Irving Medical Center, New York Presbyterian Hospital
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Icahn School of Medicine at Mount Sinai
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Rush University Medical Center
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Indiana University School of Medicine
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Boston University Chobanian & Avedisian School of Medicine
Co-authored papers 33
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University of Oxford
Co-authored papers 29
Yale University
Co-authored papers 28
Indiana University School of Medicine
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University of Washington
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Brigham Young University
Co-authored papers 24
University of Washington
Co-authored papers 22
Mayo Clinic Florida
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Boston University School of Medicine
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Columbia University Medical Center
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Wien Center for Alzheimer's Disease and Memory Disorders, Mount Sinai Medical Center
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Mayo Clinic Rochester
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University of California Davis
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Mayo Clinic
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