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Author Details

Dirk G Kieback
Helios Medical Centre
1982
124
32
PMIDPaper TitleJournal TitlePublished Year
30420699Pathway-based subnetworks enable cross-disease biomarker discovery.Nat Commun2018
29917140Predictive Biomarkers for Endocrine Therapy: Retrospective Study in Tamoxifen and Exemestane Adjuvant Multinational (TEAM) Trial.J Natl Cancer Inst2018
28649643Molecular stratification of early breast cancer identifies drug targets to drive stratified medicine.NPJ Breast Cancer2017
26717057Validation of the IHC4 Breast Cancer Prognostic Algorithm Using Multiple Approaches on the Multinational TEAM Clinical Trial.Arch Pathol Lab Med2016
24271056Effect of prior chemotherapy regimens on the efficacy of endocrine therapy within a German cohort of the TEAM trial.J Cancer Res Clin Oncol2014
25071141Mutational analysis of PI3K/AKT signaling pathway in tamoxifen exemestane adjuvant multinational pathology study.J Clin Oncol2014
24091623Do type 1 receptor tyrosine kinases inform treatment choice? A prospectively planned analysis of the TEAM trial.Br J Cancer2013
22321061Effects of exemestane and tamoxifen on hormone levels within the Tamoxifen Exemestane Adjuvant Multicentre (TEAM) trial: results of a German substudy.Climacteric2012
22993340Compliance, analgesic use and side-effect protection within a German cohort of the TEAM trial.Anticancer Res2012
23045591Mammostrat as an immunohistochemical multigene assay for prediction of early relapse risk in the tamoxifen versus exemestane adjuvant multicenter trial pathology study.J Clin Oncol2012
22467902Correlation of treatment-emergent adverse events and clinical response to endocrine therapy in early breast cancer: a retrospective analysis of the German cohort of TEAM.Ann Oncol2012
21247627Adjuvant tamoxifen and exemestane in early breast cancer (TEAM): a randomised phase 3 trial.Lancet2011
21422407Estrogen receptor and progesterone receptor as predictive biomarkers of response to endocrine therapy: a prospectively powered pathology study in the Tamoxifen and Exemestane Adjuvant Multinational trial.J Clin Oncol2011
20393978Variations in locoregional therapy in postmenopausal patients with early breast cancer treated in different countries.Br J Surg2010
20832103Endometrial effects of exemestane compared to tamoxifen within the Tamoxifen Exemestane Adjuvant Multicenter (TEAM) trial: results of a prospective gynecological ultrasound substudy.Gynecol Oncol2010
19218306Effects of exemestane and tamoxifen on bone health within the Tamoxifen Exemestane Adjuvant Multicentre (TEAM) trial: results of a German, 12-month, prospective, randomised substudy.Ann Oncol2009
19368128Adenovirus-mediated thymidine kinase gene therapy induces apoptosis in human epithelial ovarian cancer cells and damages PARP-1.In Vivo2009
19364653The effect of exemestane or tamoxifen on markers of bone turnover: results of a German sub-study of the Tamoxifen Exemestane Adjuvant Multicentre (TEAM) trial.Breast2009
18589209Society of gynecologic oncologists position paper: breast cancer care.Gynecol Oncol2008
19287072Adenovirus-mediated thymidine kinase gene therapy and coxsackie adenovirus receptor expression in ovarian cancer cells.Cancer Genomics Proteomics2008
19035280Persistent adenovirus-mediated thymidine kinase gene expression in ovarian cancer cells increases cell killing efficacy over time.Anticancer Res2008
18609356Post-cesarean adhesions--are they a unique entity?J Matern Fetal Neonatal Med2008
17595779Duration of chemotherapy with topotecan influences survival in recurrent ovarian cancer: a meta-analysis.Anticancer Res2007
16360811Two functionally relevant polymorphisms in the human progesterone receptor gene (+331 G/A and progins) and the predisposition for breast and/or ovarian cancer.Gynecol Oncol2006
17094433Combination of local, non-viral IL12 gene therapy and systemic paclitaxel chemotherapy in a syngeneic ID8 mouse model for human ovarian cancer.Anticancer Res2006
16886597Comparison of ID8 MOSE and VEGF-modified ID8 cell lines in an immunocompetent animal model for human ovarian cancer.Anticancer Res2006
15726651Aberrations in the progesterone receptor gene and the risk of recurrent endometrial carcinoma.J Pathol2005
15742119Midline intravaginal slingplasty for treatment of urinary stress incontinence: results of an independent audit up to 2 years after surgery.Int Urogynecol J Pelvic Floor Dysfunct2005
15069551Expression of splicing factors in human ovarian cancer.Oncol Rep2004
15579801A germline variation in the progesterone receptor gene increases transcriptional activity and may modify ovarian cancer risk.J Clin Endocrinol Metab2004
15475371Functional characterization of somatic point mutations of the human estrogen receptor alpha (hERalpha) in adenomyosis uteri.Mol Hum Reprod2004
15347897Aggressive management of recurrent ovarian cancer--the challenge of individualizing cancer therapy illustrated by a case report.Onkologie2004
14751192Survival after relapse in patients with endometrial cancer: results from a randomized trial. C.L. Creutzberg, W.L.J. van Putten, P.C. Koper, et al., Gynecologic Oncology 89 (2003) 201-209.Gynecol Oncol2004
14998846Reduced cardiotoxicity and comparable efficacy in a phase III trial of pegylated liposomal doxorubicin HCl (CAELYX/Doxil) versus conventional doxorubicin for first-line treatment of metastatic breast cancer.Ann Oncol2004
12796366Improvements in quality of life and disease-related symptoms in phase I trials of the selective oral epidermal growth factor receptor tyrosine kinase inhibitor ZD1839 in non-small cell lung cancer and other solid tumors.Clin Cancer Res2003
12969777European experience with a novel noninvasive sensor for intra-amniotic or extra-amniotic evaluation of fetal oxygen saturation.J Soc Gynecol Investig2003
12969718A mutated progesterone receptor allele is more prevalent in unexplained infertility.Fertil Steril2003
12881384Multicenter phase II study of oral capecitabine (Xeloda(")) in patients with metastatic breast cancer relapsing after treatment with a taxane-containing therapy.Ann Oncol2003
14612905Tissue and plasma expression of the angiogenic peptide adrenomedullin in breast cancer.Br J Cancer2003
12810206Combination of adenovirus-mediated thymidine kinase gene therapy with cytotoxic chemotherapy in bladder cancer in vitro.Urol Oncol2003
12771526Adnexal masses in pregnancy.Onkologie2003
11812094Evaluation of patients after extraperitoneal lymph node dissection and subsequent radiotherapy for cervical cancer.Gynecol Oncol2002
12530044Experience with the Advanced Breast Biopsy Instrumentation (ABBI) system.Anticancer Res2002
12409327Phase I safety, pharmacokinetic, and pharmacodynamic trial of ZD1839, a selective oral epidermal growth factor receptor tyrosine kinase inhibitor, in patients with five selected solid tumor types.J Clin Oncol2002
11961671Intraperitoneal adenovirus-mediated suicide gene therapy in combination with either topotecan or paclitaxel in nude mice with human ovarian cancer.Cancer Gene Ther2002
12009393Adenovirus-mediated thymidine kinase gene therapy for recurrent ovarian cancer: expression of coxsackie-adenovirus receptor and integrins alphavbeta3 and alphavbeta5.J Soc Gynecol Investig2002
12119458Molecular mechanisms in signal transduction: new targets for the therapy of gynecologic malignancies.Onkologie2002
11860538Histologic and immunohistochemical analysis of tissue response to adenovirus-mediated herpes simplex thymidine kinase gene therapy of ovarian cancer.Int J Gynecol Cancer2002
11455218Topotecan chemotherapy in patients with breast cancer and brain metastases: results of a pilot study.Onkologie2001
11299828Immunohistochemical detection of lymph node metastases in node-negative breast cancer patients.Anticancer Res2001
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Collaborators

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National and Kapodistrian University of Athens
Co-authored papers 10
Institute of Cancer and Genomic Sciences, The University of Birmingham
Co-authored papers 10
Erasmus Medical Center
Co-authored papers 10
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Co-authored papers 9
University of Edinburgh
Co-authored papers 9
Houston Methodist Hospital
Co-authored papers 9
Leicester Clinical Trials Unit, University of Leicester
Co-authored papers 5
University of Edinburgh
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Center for Coregulator Research, Baylor College of Medicine
Co-authored papers 3
Queen Elizabeth University Hospital
Co-authored papers 3
Ontario Institute of Cancer Research, MaRS Institute
Co-authored papers 3
University of Toronto, Canada Odette Cancer Centre
Co-authored papers 2
MRC Institute of Genetics and Molecular Medicine, University of Edinburgh
Co-authored papers 2
Baylor College of Medicine
Co-authored papers 2
University of Oxford
Co-authored papers 2
University of California los angeles
Co-authored papers 2
Ontario Institute for Cancer Research
Co-authored papers 2
Ontario Institute for Cancer Research
Co-authored papers 2
Institute of Cancer Research
Co-authored papers 2
University of Guelph
Co-authored papers 2
Ontario Institute for Cancer Research
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Medical University of Innsbruck
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Basser Center for BRCA, Abramson Cancer Center, University of Pennsylvania
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Ontario Institute for Cancer Research
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Ontario Institute for Cancer Research
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