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Author Details

Clinton Yu
University of California Irvine
2014
47
16
Andrej Sali (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
36543169Discovery, structure, and function of filamentous 3-methylcrotonyl-CoA carboxylase.Structure2023
37595580The Hippo pathway noncanonically drives autophagy and cell survival in response to energy stress.Mol Cell2023
38014020Proximity Labeling Expansion Microscopy (PL-ExM) resolves structure of the interactome.bioRxiv2023
37904046Structural surfaceomics reveals an AML-specific conformation of integrin β<sub>2</sub> as a CAR T cellular therapy target.Nat Cancer2023
37410820Structural basis of gRNA stabilization and mRNA recognition in trypanosomal RNA editing.Science2023
37406423New advances in cross-linking mass spectrometry toward structural systems biology.Curr Opin Chem Biol2023
36652389Exploring an Alternative Cysteine-Reactive Chemistry to Enable Proteome-Wide PPI Analysis by Cross-Linking Mass Spectrometry.Anal Chem2023
34763062The Ubiquitin Interacting Motif-Like Domain of Met4 Selectively Binds K48 Polyubiquitin Chains.Mol Cell Proteomics2022
35948006Discovery of compounds that reactivate p53 mutants in vitro and in vivo.Cell Chem Biol2022
35027733The Hippo pathway kinases LATS1 and LATS2 attenuate cellular responses to heavy metals through phosphorylating MTF1.Nat Cell Biol2022
35235311Two-Dimensional Fractionation Method for Proteome-Wide Cross-Linking Mass Spectrometry Analysis.Anal Chem2022
35292538Structure and conformational dynamics of <i>Clostridioides difficile</i> toxin A.Life Sci Alliance2022
35193351Developing a Targeted Quantitative Strategy for Sulfoxide-Containing MS-Cleavable Cross-Linked Peptides to Probe Conformational Dynamics of Protein Complexes.Anal Chem2022
34314389Anterograde regulation of mitochondrial genes and FGF21 signaling by hepatic LSD1.JCI Insight2021
33602808Inhibitors of cullin-RING E3 ubiquitin ligase 4 with antitumor potential.Proc Natl Acad Sci U S A2021
33915260Enabling Photoactivated Cross-Linking Mass Spectrometric Analysis of Protein Complexes by Novel MS-Cleavable Cross-Linkers.Mol Cell Proteomics2021
34761751Branched ubiquitin chain binding and deubiquitination by UCH37 facilitate proteasome clearance of stress-induced inclusions.Elife2021
34550675Developing a Bimolecular Affinity Purification Strategy to Isolate 26S Proteasome Holocomplexes for Complex-Centric Proteomic Analysis.Anal Chem2021
34389466Characterization of an A3G-Vif<sub>HIV-1</sub>-CRL5-CBFβ Structure Using a Cross-linking Mass Spectrometry Pipeline for Integrative Modeling of Host-Pathogen Complexes.Mol Cell Proteomics2021
34349018Protein interaction landscapes revealed by advanced in vivo cross-linking-mass spectrometry.Proc Natl Acad Sci U S A2021
32202417Exploring Spacer Arm Structures for Designs of Asymmetric Sulfoxide-Containing MS-Cleavable Cross-Linkers.Anal Chem2020
31950832IKK-Mediated Regulation of the COP9 Signalosome via Phosphorylation of CSN5.J Proteome Res2020
32034103Structural dynamics of the human COP9 signalosome revealed by cross-linking mass spectrometry and integrative modeling.Proc Natl Acad Sci U S A2020
33378677Quality-Control Mechanism for Telomerase RNA Folding in the Cell.Cell Rep2020
32614436Poly(A) binding KPAF4/5 complex stabilizes kinetoplast mRNAs in Trypanosoma brucei.Nucleic Acids Res2020
32525871Proteomic profiling of the monothiol glutaredoxin Grx3 reveals its global role in the regulation of iron dependent processes.PLoS Genet2020
30635574Pentatricopeptide repeat poly(A) binding protein KPAF4 stabilizes mitochondrial mRNAs in Trypanosoma brucei.Nat Commun2019
30948514Human red and green cone opsins are <i>O</i>-glycosylated at an N-terminal Ser/Thr-rich domain conserved in vertebrates.J Biol Chem2019
30723094Probing H<sub>2</sub>O<sub>2</sub>-mediated Structural Dynamics of the Human 26S Proteasome Using Quantitative Cross-linking Mass Spectrometry (QXL-MS).Mol Cell Proteomics2019
29160693Cross-Linking Mass Spectrometry: An Emerging Technology for Interactomics and Structural Biology.Anal Chem2018
29792801Development of a Novel Sulfoxide-Containing MS-Cleavable Homobifunctional Cysteine-Reactive Cross-Linker for Studying Protein-Protein Interactions.Anal Chem2018
29337983Wor1 establishes opaque cell fate through inhibition of the general co-repressor Tup1 in Candida albicans.PLoS Genet2018
28821611The proteasome-interacting Ecm29 protein disassembles the 26S proteasome in response to oxidative stress.J Biol Chem2017
28292943Molecular Details Underlying Dynamic Structures and Regulation of the Human 26S Proteasome.Mol Cell Proteomics2017
29149597Structural Basis for Shelterin Bridge Assembly.Mol Cell2017
28807855Spatial Organization and Molecular Interactions of the Schizosaccharomyces pombe Ccq1-Tpz1-Poz1 Shelterin Complex.J Mol Biol2017
27114451Characterization of Dynamic UbR-Proteasome Subcomplexes by In vivo Cross-linking (X) Assisted Bimolecular Tandem Affinity Purification (XBAP) and Label-free Quantitation.Mol Cell Proteomics2016
27669733Mechanisms Underlying Acrolein-Mediated Inhibition of Chromatin Assembly.Mol Cell Biol2016
27626298Developing a Multiplexed Quantitative Cross-Linking Mass Spectrometry Platform for Comparative Structural Analysis of Protein Complexes.Anal Chem2016
27417384Developing an Acidic Residue Reactive and Sulfoxide-Containing MS-Cleavable Homobifunctional Cross-Linker for Probing Protein-Protein Interactions.Anal Chem2016
25823605Synthesis of two new enrichable and MS-cleavable cross-linkers to define protein-protein interactions by mass spectrometry.Org Biomol Chem2015
26632597Gln40 deamidation blocks structural reconfiguration and activation of SCF ubiquitin ligase complex by Nedd8.Nat Commun2015
26446259Activation of m1 muscarinic acetylcholine receptor induces surface transport of KCNQ channels through a CRMP-2-mediated pathway.J Cell Sci2015
26365187Dissecting Fission Yeast Shelterin Interactions via MICro-MS Links Disruption of Shelterin Bridge to Tumorigenesis.Cell Rep2015
24471733Developing new isotope-coded mass spectrometry-cleavable cross-linkers for elucidating protein structures.Anal Chem2014
24423446Characterizing the dynamics of proteasome complexes by proteomics approaches.Antioxid Redox Signal2014
25253489A new in vivo cross-linking mass spectrometry platform to define protein-protein interactions in living cells.Mol Cell Proteomics2014
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Collaborators

Lan Huang
University of California Irvine
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Scott D Rychnovsky
University of California irvine
Co-authored papers 18
Xiaorong Wang
University of California Irvine
Co-authored papers 11
Eric J Novitsky
University of California irvine
Co-authored papers 8
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Co-authored papers 6
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J. David Gladstone Institutes
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Co-authored papers 4
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Co-authored papers 3
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Co-authored papers 3
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University of Washington
Co-authored papers 3
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ShanghaiTech University
Co-authored papers 3
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Center for Cancer Research, National Cancer Institute, National Institutes of Health
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Andrea Sinz
Center for Structural Mass Spectrometry, Martin Luther University Halle-Wittenberg
Co-authored papers 1
Yihong Ye
National Institute of Diabetes, National Institutes of Health
Co-authored papers 1
Eri Sakata
Max Planck Institute of Biochemistry
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John Gross
Co-authored papers 1
Michael R Hoopmann
Institute for Systems Biology
Co-authored papers 1
David Fushman
University of Maryland, College Park
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Hai Minh Ta
Baylor College of Medicine
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Abdullah Kahraman
University of Zurich
Co-authored papers 1
Paolo Nanni
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Florian Beck
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