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Author Details

Henry Yang
Cancer Science Institute of Singapore, National University of Singapore
2005
137
48
Jake Y. Chen (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
36796022Core-binding factor fusion downregulation of ADAR2 RNA editing contributes to AML leukemogenesis.Blood2023
37477572Third-Generation Single-Molecule Sequencing for Preimplantation Genetic Testing of Aneuploidy and Segmental Imbalances.Clin Chem2023
36638333Targeting RNA Exonuclease XRN1 Potentiates Efficacy of Cancer Immunotherapy.Cancer Res2023
36796022Core-binding factor fusion downregulation of ADAR2 RNA editing contributes to AML leukemogenesis.Blood2023
37477572Third-Generation Single-Molecule Sequencing for Preimplantation Genetic Testing of Aneuploidy and Segmental Imbalances.Clin Chem2023
36638333Targeting RNA Exonuclease XRN1 Potentiates Efficacy of Cancer Immunotherapy.Cancer Res2023
34615655Sex-Biased <i>ZRSR2</i> Mutations in Myeloid Malignancies Impair Plasmacytoid Dendritic Cell Activation and Apoptosis.Cancer Discov2022
35523948Correction: PLK1 inhibition selectively induces apoptosis in ARID1A deficient cells through uncoupling of oxygen consumption from ATP production.Oncogene2022
35511868A Runx1-enhancer Element eR1 Identified Lineage Restricted Mammary Luminal Stem Cells.Stem Cells2022
36217548Oncofetal protein IGF2BP1 regulates IQGAP3 expression to maintain stem cell potential in cancer.iScience2022
35379802Multilayered control of splicing regulatory networks by DAP3 leads to widespread alternative splicing changes in cancer.Nat Commun2022
35618746Pan-cancer pervasive upregulation of 3' UTR splicing drives tumourigenesis.Nat Cell Biol2022
35411071Non-coding RNA LEVER sequestration of PRC2 can mediate long range gene regulation.Commun Biol2022
33676077Npac Is A Co-factor of Histone H3K36me3 and Regulates Transcriptional Elongation in Mouse Embryonic Stem Cells.Genomics Proteomics Bioinformatics2022
35314703ADARs act as potent regulators of circular transcriptome in cancer.Nat Commun2022
35236967PLK1 inhibition selectively induces apoptosis in ARID1A deficient cells through uncoupling of oxygen consumption from ATP production.Oncogene2022
34615655Sex-Biased <i>ZRSR2</i> Mutations in Myeloid Malignancies Impair Plasmacytoid Dendritic Cell Activation and Apoptosis.Cancer Discov2022
35190641p53-NEIL1 co-abnormalities induce genomic instability and promote synthetic lethality with Chk1 inhibition in multiple myeloma having concomitant 17p13(del) and 1q21(gain).Oncogene2022
35022315KDM6A Depletion in Breast Epithelial Cells Leads to Reduced Sensitivity to Anticancer Agents and Increased TGFβ Activity.Mol Cancer Res2022
35077445T and NK cell lymphoma cell lines do not rely on ZAP-70 for survival.PLoS One2022
35074568A Point Mutation R122C in RUNX3 Promotes the Expansion of Isthmus Stem Cells and Inhibits Their Differentiation in the Stomach.Cell Mol Gastroenterol Hepatol2022
35195778Global analysis of RNA-binding proteins identifies a positive feedback loop between LARP1 and MYC that promotes tumorigenesis.Cell Mol Life Sci2022
35511868A Runx1-enhancer Element eR1 Identified Lineage Restricted Mammary Luminal Stem Cells.Stem Cells2022
35411071Non-coding RNA LEVER sequestration of PRC2 can mediate long range gene regulation.Commun Biol2022
35379802Multilayered control of splicing regulatory networks by DAP3 leads to widespread alternative splicing changes in cancer.Nat Commun2022
35523948Correction: PLK1 inhibition selectively induces apoptosis in ARID1A deficient cells through uncoupling of oxygen consumption from ATP production.Oncogene2022
35618746Pan-cancer pervasive upregulation of 3' UTR splicing drives tumourigenesis.Nat Cell Biol2022
36217548Oncofetal protein IGF2BP1 regulates IQGAP3 expression to maintain stem cell potential in cancer.iScience2022
33676077Npac Is A Co-factor of Histone H3K36me3 and Regulates Transcriptional Elongation in Mouse Embryonic Stem Cells.Genomics Proteomics Bioinformatics2022
35190641p53-NEIL1 co-abnormalities induce genomic instability and promote synthetic lethality with Chk1 inhibition in multiple myeloma having concomitant 17p13(del) and 1q21(gain).Oncogene2022
35074568A Point Mutation R122C in RUNX3 Promotes the Expansion of Isthmus Stem Cells and Inhibits Their Differentiation in the Stomach.Cell Mol Gastroenterol Hepatol2022
35314703ADARs act as potent regulators of circular transcriptome in cancer.Nat Commun2022
35236967PLK1 inhibition selectively induces apoptosis in ARID1A deficient cells through uncoupling of oxygen consumption from ATP production.Oncogene2022
35022315KDM6A Depletion in Breast Epithelial Cells Leads to Reduced Sensitivity to Anticancer Agents and Increased TGFβ Activity.Mol Cancer Res2022
35195778Global analysis of RNA-binding proteins identifies a positive feedback loop between LARP1 and MYC that promotes tumorigenesis.Cell Mol Life Sci2022
35077445T and NK cell lymphoma cell lines do not rely on ZAP-70 for survival.PLoS One2022
33971010Myeloid lncRNA LOUP mediates opposing regulatory effects of RUNX1 and RUNX1-ETO in t(8;21) AML.Blood2021
33971010Myeloid lncRNA LOUP mediates opposing regulatory effects of RUNX1 and RUNX1-ETO in t(8;21) AML.Blood2021
34120146Metabolic alterations mediated by STAT3 promotes drug persistence in CML.Leukemia2021
33984347The Polyamine Regulator AMD1 Upregulates Spermine Levels to Drive Epidermal Differentiation.J Invest Dermatol2021
33598459PATZ1 (MAZR) Co-occupies Genomic Sites With p53 and Inhibits Liver Cancer Cell Proliferation via Regulating p27.Front Cell Dev Biol2021
34348892Repurposing RNA sequencing for discovery of RNA modifications in clinical cohorts.Sci Adv2021
34597139Pseudogene-mediated DNA demethylation leads to oncogene activation.Sci Adv2021
33598459PATZ1 (MAZR) Co-occupies Genomic Sites With p53 and Inhibits Liver Cancer Cell Proliferation via Regulating p27.Front Cell Dev Biol2021
34597139Pseudogene-mediated DNA demethylation leads to oncogene activation.Sci Adv2021
34348892Repurposing RNA sequencing for discovery of RNA modifications in clinical cohorts.Sci Adv2021
33984347The Polyamine Regulator AMD1 Upregulates Spermine Levels to Drive Epidermal Differentiation.J Invest Dermatol2021
34120146Metabolic alterations mediated by STAT3 promotes drug persistence in CML.Leukemia2021
31603498dbInDel: a database of enhancer-associated insertion and deletion variants by analysis of H3K27ac ChIP-Seq.Bioinformatics2020
32183236<i>miR-7</i> Controls the Dopaminergic/Oligodendroglial Fate through Wnt/β-catenin Signaling Regulation.Cells2020
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Collaborators

Harvard Stem Cell Institute, Harvard Medical School
Co-authored papers 24
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Kyoto University
Co-authored papers 11
University of Alabama at Birmingham
Co-authored papers 10
Taussig Cancer Institute, Cleveland Clinic
Co-authored papers 7
Tokyo Medical and Dental University
Co-authored papers 6
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Tokyo Medical and Dental University (TMDU)
Co-authored papers 5
Co-authored papers 4
Cancer Science Institute of Singapore, National University of Singapore
Co-authored papers 4
Oregon Health & Science University School of Medicine
Co-authored papers 4
The University of Texas MD Anderson Cancer Center
Co-authored papers 4
The University of Texas MD Anderson Cancer Center
Co-authored papers 4
Co-authored papers 3
Cancer Science Institute of Singapore, National University of Singapore
Co-authored papers 3
Co-authored papers 3
Co-authored papers 3
National Taiwan University College of Medicine
Co-authored papers 2
Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai
Co-authored papers 2
Vanderbilt University
Co-authored papers 2
The University of Alabama at Birmingham School of Medicine
Co-authored papers 2
Tokyo Medical and Dental University
Co-authored papers 2
Gladstone Institutes
Co-authored papers 2
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Cancer Institute of Singapore, National University of Singapore
Co-authored papers 2
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Boston Children's Hospital, Harvard Medical School
Co-authored papers 2
Harvard Medical School
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USA The Jackson Laboratory Cancer Center
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