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Author Details

Arthur Wuster
Genentech Inc.
2008
26
16
Nevan J Krogan (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
37079518Rare CIDEC coding variants enriched in age-related macular degeneration patients with small low-luminance deficit cause lipid droplet and fat storage defects.PLoS One2023
37647852SLC6A1 variant pathogenicity, molecular function and phenotype: a genetic and clinical analysis.Brain2023
33850126Identifying therapeutic drug targets using bidirectional effect genes.Nat Commun2021
29550837Previously reported placebo-response-associated variants do not predict patient outcomes in inflammatory disease Phase III trial placebo arms.Genes Immun2019
30997344Influence of genetic copy number variants of the human GLUT3 glucose transporter gene <i>SLC2A3</i> on protein expression, glycolysis and rheumatoid arthritis risk: A genetic replication study.Mol Genet Metab Rep2019
30366082Enabling genome-wide association testing with multiple diseases and no healthy controls.Gene2019
30510070LACC1 Regulates TNF and IL-17 in Mouse Models of Arthritis and Inflammation.J Immunol2019
30388101Paired Immunoglobulin-like Type 2 Receptor Alpha G78R variant alters ligand binding and confers protection to Alzheimer's disease.PLoS Genet2018
30181241Cells alter their tRNA abundance to selectively regulate protein synthesis during stress conditions.Sci Signal2018
31022698Inflammatory Bowel Disease Susceptibility Gene <i>C1ORF106</i> Regulates Intestinal Epithelial Permeability.Immunohorizons2018
30463956Germline genetic polymorphisms influence tumor gene expression and immune cell infiltration.Proc Natl Acad Sci U S A2018
28035029geneAttribution: trait agnostic identification of candidate genes associated with noncoding variation.Bioinformatics2017
28235197An Organismal CNV Mutator Phenotype Restricted to Early Human Development.Cell2017
28696253The Ox40/Ox40 Ligand Pathway Promotes Pathogenic Th Cell Responses, Plasmablast Accumulation, and Lupus Nephritis in NZB/W F1 Mice.J Immunol2017
28827725Estimating the human mutation rate from autozygous segments reveals population differences in human mutational processes.Nat Commun2017
27023642Thinking differently about lupus.Elife2016
26656846Timing, rates and spectra of human germline mutation.Nat Genet2016
26774822Regulation of T Cell Receptor Signaling by DENND1B in TH2 Cells and Allergic Disease.Cell2016
27054363Mutational History of a Human Cell Lineage from Somatic to Induced Pluripotent Stem Cells.PLoS Genet2016
23975140DeNovoGear: de novo indel and point mutation discovery and phasing.Nat Methods2013
20024075Transcriptional control of the quorum sensing response in yeast.Mol Biosyst2010
21179023Cross-species chemogenomic profiling reveals evolutionarily conserved drug mode of action.Mol Syst Biol2010
20880955Spial: analysis of subtype-specific features in multiple sequence alignments of proteins.Bioinformatics2010
19690563Genomic analysis reveals a tight link between transcription factor dynamics and regulatory network architecture.Mol Syst Biol2009
17933897Conservation and evolutionary dynamics of the agr cell-to-cell communication system across firmicutes.J Bacteriol2008
18346803Chemogenomics and biotechnology.Trends Biotechnol2008
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Collaborators

Timothy W Behrens
Genentech Inc.
Co-authored papers 8
Madan Mohan Babu
St. Jude Children's Research Hospital
Co-authored papers 7
Tushar Bhangale
Genentech Inc.
Co-authored papers 5
Matthew E Hurles
Wellcome Sanger Institute
Co-authored papers 4
Brian L Yaspan
Genentech Inc.
Co-authored papers 4
Robert R Graham
Genentech Inc.
Co-authored papers 3
Julie Hunkapiller
Genentech Inc.
Co-authored papers 3
Richard Durbin
University of Cambridge
Co-authored papers 1
Shalini N Jhangiani
Baylor College of Medicine
Co-authored papers 1
Ken Chen
University of Texas MD Anderson Cancer Center
Co-authored papers 1
Ira Mellman
Genentech Inc.
Co-authored papers 1
Avinash Ramu
Washington University School of Medicine
Co-authored papers 1
Pengfei Liu
Co-authored papers 1
Anja Stefanski
Universitatsklinikum
Co-authored papers 1
Michiel J Noordam
Co-authored papers 1
Ward Ortmann
University of Minnesota School of Medicine
Co-authored papers 1
Chris Tyler-Smith
Wellcome Sanger Institute
Co-authored papers 1
David P Toczyski
University of California San Francisco
Co-authored papers 1
Nevan J Krogan (CM4AI)
University of California San Francisco
Co-authored papers 1
Tomasz Gambin
Institute of Computer Science, Warsaw University of Technology
Co-authored papers 1
Simon S Gao
Clinical Imaging Group, Inc.
Co-authored papers 1
Wyatt T Clark
BioMarin Pharmaceutical Inc.
Co-authored papers 1
Zeynep Coban Akdemir
Baylor College of Medicine
Co-authored papers 1
Theresa J Berens
University of California san francisco
Co-authored papers 1
Lon R Cardon
BioMarin Pharmaceutical Inc.
Co-authored papers 1
Nathalie Conte
The Wellcome Trust Sanger Institute
Co-authored papers 1
Laura Kapitzky
QB3 Institute, University of California san francisco
Co-authored papers 1
Alison M Goate
Icahn School of Medicine at Mount Sinai
Co-authored papers 1
Blair H Smith
Co-authored papers 1
Matthew L Albert
Co-authored papers 1
Release 1.2