Author details

Full Name

Suzanne J Baker

Affiliation

ORCID

Career Start Year

1989

Papers

117

H Index

Expertise

CM4AI Collaborator

PMID	Paper Title	Journal Title	Published Year
36786841	Correction to: Amplification of the PLAG-family genes-PLAGL1 and PLAGL2-isÂ a key feature of the novel tumor type CNS embryonal tumor with PLAGL amplification.	Acta Neuropathol	2023
36437415	Amplification of the PLAG-family genes-PLAGL1 and PLAGL2-isÂ a key feature of the novel tumor type CNS embryonal tumor with PLAGL amplification.	Acta Neuropathol	2023
36971093	ATM inhibition enhances the efficacy of radiation across distinct molecular subgroups of pediatric high-grade glioma.	Neuro Oncol	2023
37119408	Oncohistones and disrupted development in pediatric-type diffuse high-grade glioma.		2023
35403869	Somatic LINE-1 promoter acquisition drives oncogenic FOXR2 activation in pediatric brain tumor.	Acta Neuropathol	2022
35584667	H3-K27M-mutant nucleosomes interact with MLL1 to shape the glioma epigenetic landscape.	Cell Reports	2022
35642016	Convergent evolution and multi-wave clonal invasion in H3 K27-altered diffuse midline gliomas treated with a PDGFR inhibitor.	Acta Neuropathol Commun	2022
35802025	FOXR2 Is an Epigenetically Regulated Pan-Cancer Oncogene That Activates ETS Transcriptional Circuits.	Cancer Res	2022
34644147	Epigenetically defined therapeutic targeting in H3.3G34R/V high-grade gliomas.	Sci Transl Med	2021
33749791	NTRK Fusions Can Co-Occur With H3K27M Mutations and May Define Druggable Subclones Within Diffuse Midline Gliomas.	J Neuropathol Exp Neurol	2021
34215733	Patient-derived models recapitulate heterogeneity of molecular signatures and drug response in pediatric high-grade glioma.	Nat Commun	2021
33939327	Model-based evaluation of image-guided fractionated whole-brain radiation therapy in pediatric diffuse intrinsic pontine glioma xenografts.	CPT Pharmacometrics Syst Pharmacol	2021
33320196	Cell-surface antigen profiling of pediatric brain tumors: B7-H3 is consistently expressed and can be targeted via local or systemic CAR T-cell delivery.	Neuro Oncol	2021
33434514	Exploration of Coding and Non-coding Variants in Cancer Using GenomePaint.	Cancer Cell	2021
34545084	Comprehensive molecular characterization of pediatric radiation-induced high-grade glioma.	Nat Commun	2021
32832624	RACK7 recognizes H3.3G34R mutation to suppress expression of MHC class II complex components and their delivery pathway in pediatric glioblastoma.	Science advances	2020
32326973	Clinical, imaging, and molecular analysis of pediatric pontine tumors lacking characteristic imaging features of DIPG.	Acta Neuropathol Commun	2020
31785339	Defining Optimal Target Volumes of Conformal Radiation Therapy for Diffuse Intrinsic Pontine Glioma.	International Journal of Radiation Oncology Biology Physics	2020
32238360	Infant High-Grade Gliomas Comprise Multiple Subgroups Characterized by Novel Targetable Gene Fusions and Favorable Outcomes.	Cancer Discov	2020
31566663	ChIPseqSpikeInFree: a ChIP-seq normalization approach to reveal global changes in histone modifications without spike-in.	Bioinformatics	2020
31859390	Invited Review: Emerging functions of histone H3 mutations in paediatric diffuse high-grade gliomas.	Neuropathology and Applied Neurobiology	2020
33138032	RAD51-Mediated DNA Homologous Recombination Is Independent of <i>PTEN</i> Mutational Status.	Cancers (Basel)	2020
32519082	Patient-derived orthotopic xenografts of pediatric brain tumors: a St. Jude resource.	Acta Neuropathol	2020
30770999	H3.3 K27M depletion increases differentiation and extends latency of diffuse intrinsic pontine glioma growth in vivo.	Acta Neuropathol	2019
30267146	Structure and evolution of double minutes in diagnosis and relapse brain tumors.	Acta Neuropathol	2019
30595505	Histone H3.3 K27M Accelerates Spontaneous Brainstem Glioma and Drives Restricted Changes in Bivalent Gene Expression.	Cancer Cell	2019
30324526	Engineering Inducible Knock-In Mice to Model Oncogenic Brain Tumor Mutations from Endogenous Loci.	Methods Mol Biol	2019
30976974	Correction to: H3.3 K27M depletion increases differentiation and extends latency of diffuse intrinsic pontine glioma growth in vivo.	Acta Neuropathol	2019
31276589	p53: a tumor suppressor hiding in plain sight.	Journal of Molecular Cell Biology	2019
31079218	CNS penetration of the CDK4/6 inhibitor ribociclib in non-tumor bearing mice and mice bearing pediatric brain tumors.	Cancer Chemotherapy and Pharmacology	2019
31420543	Deep multiomics profiling of brain tumors identifies signaling networks downstream of cancer driver genes.	Nat Commun	2019
27815386	PTEN Signaling in the Postnatal Perivascular Progenitor Niche Drives Medulloblastoma Formation.	Cancer Res	2017
28966033	Integrated Molecular Meta-Analysis of 1,000 Pediatric High-Grade and Diffuse Intrinsic Pontine Glioma.	Cancer Cell	2017
27282398	Pediatric high-grade glioma: biologically and clinically in need of new thinking.	Neuro Oncol	2017
28084680	Rapid and fulminant leptomeningeal spread following radiotherapy in diffuse intrinsic pontine glioma.	Pediatr Blood Cancer	2017
26279473	Arid1a inactivation in an Apc- and Pten-defective mouse ovarian cancer model enhances epithelial differentiation and prolongs survival.	Journal of Pathology	2016
26810070	Genetic alterations in uncommon low-grade neuroepithelial tumors: BRAF, FGFR1, and MYB mutations occur at high frequency and align with morphology.	Acta Neuropathol	2016
27033070	Detecting PTEN and PI3K Signaling in Brain.	Methods in Molecular Biology	2016
26638183	Pediatric gliomas as neurodevelopmental disorders.	Glia	2016
26633882	Mouse models of human PIK3CA-related brain overgrowth have acutely treatable epilepsy.	Elife	2015
25635044	Cell of origin for malignant gliomas and its implication in therapeutic development.	Cold Spring Harbor perspectives in biology	2015
25698082	Activated mutant p110Î± causes endometrial carcinoma in the setting of biallelic Pten deletion.	Am J Pathol	2015
25938371	CONSERTING: integrating copy-number analysis with structural-variation detection.	Nat Methods	2015
24705251	The genomic landscape of diffuse intrinsic pontine glioma and pediatric non-brainstem high-grade glioma.	Nat Genet	2014
25330836	Pax3 expression enhances PDGF-B-induced brainstem gliomagenesis and characterizes a subset of brainstem glioma.	Acta Neuropathol Commun	2014
25219808	The genetic signatures of pediatric high-grade glioma: no longer a one-act play.	Seminars in Radiation Oncology	2014
25230881	Unique genetic and epigenetic mechanisms driving paediatric diffuse high-grade glioma.	Nature Reviews Cancer	2014
24985344	A unified nomenclature and amino acid numbering for human PTEN.	Sci Signal	2014
24710217	The landscape of somatic mutations in epigenetic regulators across 1,000 paediatric cancer genomes.	Nat Commun	2014
23499052	Type I to type II ovarian carcinoma progression: mutant Trp53 or Pik3ca confers a more aggressive tumor phenotype in a mouse model of ovarian cancer.	American Journal of Pathology	2013