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Author Details

Melanie Spears
Ontario Institute for Cancer Research
2008
18
10
PMIDPaper TitleJournal TitlePublished Year
31322299Benchmarking to the Gold Standard: Hyaluronan-Oxime Hydrogels Recapitulate Xenograft Models with In Vitro Breast Cancer Spheroid Culture.Adv Mater2019
35100692Identification of Distinct Prognostic Groups: Implications for Patient Selection to Targeted Therapies Among Anti-Endocrine Therapy-Resistant Early Breast Cancers.JCO Precis Oncol2019
29618387Deregulation of the spindle assembly checkpoint is associated with paclitaxel resistance in ovarian cancer.J Ovarian Res2018
28659176ISOWN: accurate somatic mutation identification in the absence of normal tissue controls.Genome Med2017
27056899A four gene signature of chromosome instability (CIN4) predicts for benefit from taxanes in the NCIC-CTG MA21 clinical trial.Oncotarget2016
26852132Downregulation of histone H2A and H2B pathways is associated with anthracycline sensitivity in breast cancer.Breast Cancer Res2016
26372731A four gene signature predicts benefit from anthracyclines: evidence from the BR9601 and MA.5 clinical trials.Oncotarget2015
24402423Validated or not validated? That is the question.J Natl Cancer Inst2014
25312014Molecular characterisation of isogenic taxane resistant cell lines identify novel drivers of drug resistance.BMC Cancer2014
23152120Authors' reply.J Pathol2013
21390497The p160 ER co-regulators predict outcome in ER negative breast cancer.Breast Cancer Res Treat2012
22562124Expression of activated type I receptor tyrosine kinases in early breast cancer.Breast Cancer Res Treat2012
22430898Proximity ligation assays for isoform-specific Akt activation in breast cancer identify activated Akt1 as a driver of progression.J Pathol2012
21638049In situ detection of HER2:HER2 and HER2:HER3 protein-protein interactions demonstrates prognostic significance in early breast cancer.Breast Cancer Res Treat2012
20700126In situ quantification of HER2-protein tyrosine kinase 6 (PTK6) protein-protein complexes in paraffin sections from breast cancer tissues.Br J Cancer2010
19456271The potential role of estrogen receptors and the SRC family as targets for the treatment of breast cancer.Expert Opin Ther Targets2009
19925033Human epidermal growth factor receptor dimerization analysis in breast cancer diagnosis: potential for improving testing accuracy and treatment selection.Mol Diagn Ther2009
20477393Type I receptor tyrosine kinases as predictive or prognostic markers in early breast cancer.Biomark Med2008
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Collaborators

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UCL Great Ormond Street Institute of Child Health, University College London
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Juravinski Hospital and Cancer Center
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Ontario Institute for Cancer Research
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Ontario Institute of Cancer Research, MaRS Institute
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Queens University
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