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Author Details

E Alejandro Sweet-Cordero
University of California San Francisco
1989
81
35
Nathan Sheffield (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
37400538Discovery of VH domains that allosterically inhibit ENPP1.Nat Chem Biol2024
37703185Osteosarcoma PDX-Derived Cell Line Models for Preclinical Drug Evaluation Demonstrate Metastasis Inhibition by Dinaciclib through a Genome-Targeted Approach.Clin Cancer Res2024
37400538Discovery of VH domains that allosterically inhibit ENPP1.Nat Chem Biol2024
37703185Osteosarcoma PDX-Derived Cell Line Models for Preclinical Drug Evaluation Demonstrate Metastasis Inhibition by Dinaciclib through a Genome-Targeted Approach.Clin Cancer Res2024
36711882Development and characterization of new patient-derived xenograft (PDX) models of osteosarcoma with distinct metastatic capacities.bioRxiv2023
37933765Pre-and post-HSCT use of TKI therapy for fusion-driven B-ALL: A case series of five pediatric, adolescent and young adult patients.Cancer Rep (Hoboken)2023
36711882Development and characterization of new patient-derived xenograft (PDX) models of osteosarcoma with distinct metastatic capacities.bioRxiv2023
37205599FET fusion oncoproteins disrupt physiologic DNA repair networks in cancer.bioRxiv2023
37398210FET fusion oncoproteins disrupt physiologic DNA repair networks and induce ATR synthetic lethality in cancer.Res Sq2023
37001527Generation and multi-dimensional profiling of a childhood cancer cell line atlas defines new therapeutic opportunities.Cancer Cell2023
37933765Pre-and post-HSCT use of TKI therapy for fusion-driven B-ALL: A case series of five pediatric, adolescent and young adult patients.Cancer Rep (Hoboken)2023
37205599FET fusion oncoproteins disrupt physiologic DNA repair networks in cancer.bioRxiv2023
37001527Generation and multi-dimensional profiling of a childhood cancer cell line atlas defines new therapeutic opportunities.Cancer Cell2023
37398210FET fusion oncoproteins disrupt physiologic DNA repair networks and induce ATR synthetic lethality in cancer.Res Sq2023
35321431APOBEC Mutational Signature and Tumor Mutational Burden as Predictors of Clinical Outcomes and Treatment Response in Patients With Advanced Urothelial Cancer.Front Oncol2022
35594991Discovery Proteomics Analysis Determines That Driver Oncogenes Suppress Antiviral Defense Pathways Through Reduction in Interferon-β Autocrine Stimulation.Mol Cell Proteomics2022
35767377A 3D Osteosarcoma Model with Bone-Mimicking Cues Reveals a Critical Role of Bone Mineral and Informs Drug Discovery.Adv Healthc Mater2022
36008377Single-cell analysis of hepatoblastoma identifies tumor signatures that predict chemotherapy susceptibility using patient-specific tumor spheroids.Nat Commun2022
35740503Synthetic Vulnerabilities in the KRAS Pathway.Cancers (Basel)2022
35927023Detection of a GLIS3 fusion in an infant with AML refractory to chemotherapy.Cold Spring Harb Mol Case Stud2022
36316687Ganciclovir-induced mutations are present in a diverse spectrum of post-transplant malignancies.Genome Med2022
35321431APOBEC Mutational Signature and Tumor Mutational Burden as Predictors of Clinical Outcomes and Treatment Response in Patients With Advanced Urothelial Cancer.Front Oncol2022
35740503Synthetic Vulnerabilities in the KRAS Pathway.Cancers (Basel)2022
35767377A 3D Osteosarcoma Model with Bone-Mimicking Cues Reveals a Critical Role of Bone Mineral and Informs Drug Discovery.Adv Healthc Mater2022
35594991Discovery Proteomics Analysis Determines That Driver Oncogenes Suppress Antiviral Defense Pathways Through Reduction in Interferon-β Autocrine Stimulation.Mol Cell Proteomics2022
35927023Detection of a GLIS3 fusion in an infant with AML refractory to chemotherapy.Cold Spring Harb Mol Case Stud2022
36008377Single-cell analysis of hepatoblastoma identifies tumor signatures that predict chemotherapy susceptibility using patient-specific tumor spheroids.Nat Commun2022
36316687Ganciclovir-induced mutations are present in a diverse spectrum of post-transplant malignancies.Genome Med2022
32815876NUP98-NSD1 Driven MDS/MPN in Childhood Masquerading as JMML.J Pediatr Hematol Oncol2021
34353895A Comprehensive Circulating Tumor DNA Assay for Detection of Translocation and Copy-Number Changes in Pediatric Sarcomas.Mol Cancer Ther2021
32929263Oncoprotein-specific molecular interaction maps (SigMaps) for cancer network analyses.Nat Biotechnol2021
32815876NUP98-NSD1 Driven MDS/MPN in Childhood Masquerading as JMML.J Pediatr Hematol Oncol2021
34944883Comparison of the Transcriptomic Signatures in Pediatric and Adult CML.Cancers (Basel)2021
34944883Comparison of the Transcriptomic Signatures in Pediatric and Adult CML.Cancers (Basel)2021
34353895A Comprehensive Circulating Tumor DNA Assay for Detection of Translocation and Copy-Number Changes in Pediatric Sarcomas.Mol Cancer Ther2021
32929263Oncoprotein-specific molecular interaction maps (SigMaps) for cancer network analyses.Nat Biotechnol2021
31511612Fusion driven JMML: a novel CCDC88C-FLT3 fusion responsive to sorafenib identified by RNA sequencing.Leukemia2020
32238925CRISPR screens in cancer spheroids identify 3D growth-specific vulnerabilities.Nature2020
31874105The Mir181ab1 cluster promotes KRAS-driven oncogenesis and progression in lung and pancreas.J Clin Invest2020
32767231Genomic Complexity of Osteosarcoma and Its Implication for Preclinical and Clinical Targeted Therapies.Adv Exp Med Biol2020
33139339An Expanded Tool Kit for Modeling the Oncogenic Functions of KRAS.Cancer Discov2020
32522868Engineering a potent receptor superagonist or antagonist from a novel IL-6 family cytokine ligand.Proc Natl Acad Sci U S A2020
33283136Complete Response to PD-1 Inhibition in an Adolescent With Relapsed Clear Cell Adenocarcinoma of the Cervix Predicted by Neoepitope Burden and APOBEC Signature.JCO Precis Oncol2020
32727735Combined Proteomic and Genetic Interaction Mapping Reveals New RAS Effector Pathways and Susceptibilities.Cancer Discov2020
33049203Advances and Challenges in Pediatric and Childhood Cancers.Cancer Cell2020
31511612Fusion driven JMML: a novel CCDC88C-FLT3 fusion responsive to sorafenib identified by RNA sequencing.Leukemia2020
31874105The Mir181ab1 cluster promotes KRAS-driven oncogenesis and progression in lung and pancreas.J Clin Invest2020
33283136Complete Response to PD-1 Inhibition in an Adolescent With Relapsed Clear Cell Adenocarcinoma of the Cervix Predicted by Neoepitope Burden and APOBEC Signature.JCO Precis Oncol2020
33139339An Expanded Tool Kit for Modeling the Oncogenic Functions of KRAS.Cancer Discov2020
33049203Advances and Challenges in Pediatric and Childhood Cancers.Cancer Cell2020
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Collaborators

Leanne C Sayles
Co-authored papers 17
Tyler Jacks
Co-authored papers 9
Purvesh Khatri
University of California San Francisco
Co-authored papers 5
Heng-Yi Liu
Co-authored papers 5
Aviv Spillinger
Co-authored papers 5
Monte M Winslow
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Co-authored papers 4
Arun Rangaswami
Co-authored papers 4
Norman J Lacayo
Co-authored papers 4
Julien Sage
Department of Pediatrics Stanford University Stanford California USA.
Co-authored papers 4
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Bakar Computational Health Sciences Institute, University of California san francisco
Co-authored papers 3
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Center for Cancer Research, National Cancer Institute
Co-authored papers 3
Sofie R Salama
Genomics Institute, University of California Santa Cruz
Co-authored papers 3
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UC Santa Cruz Genomics Institute
Co-authored papers 3
Todd R Golub
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Co-authored papers 3
Peter K Jackson
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Aravind Subramanian
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Stanford University.
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Kimberly Stegmaier
Dana-Farber Cancer Institute
Co-authored papers 2
Ann Durbin
Co-authored papers 2
Olivier Delattre
PSL Research University, Institut Curie Research Center, INSERM U, Institut Curie
Co-authored papers 2
Ellen T Kephart
Co-authored papers 2
Jaume Mora
Pediatric Cancer Center Barcelona, Hospital Sant Joan de Deu
Co-authored papers 2
Peyton G Greenside
Co-authored papers 2
Jason E Cain
Co-authored papers 2
Max A Horlbeck
Broad Institute of MIT and Harvard
Co-authored papers 2
Adam C Resnick
Center for Data-Driven Discovery in Biomedicine, Children's Hospital of Philadelphia
Co-authored papers 2
Aykut Uren
Georgetown University Medical Center
Co-authored papers 2
Takuro Nakamura
Tohoku University Graduate School of Medicine
Co-authored papers 2
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