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Author Details

Benjamin A Logsdon
Fred Hutchinson Cancer Research Center
2007
44
24
Trey Ideker (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
37248328Human microglia show unique transcriptional changes in Alzheimer's disease.Nat Aging2023
35197847Corrigendum: Uncovering Disease Mechanisms in a Novel Mouse Model Expressing Humanized APOEε4 and Trem2<sup>*</sup>R47H.Front Aging Neurosci2022
33417599Identifying drug targets for neurological and psychiatric disease via genetics and the brain transcriptome.PLoS Genet2021
33846625Brain proteome-wide association study implicates novel proteins in depression pathogenesis.Nat Neurosci2021
33510477Integrating human brain proteomes with genome-wide association data implicates new proteins in Alzheimer's disease pathogenesis.Nat Genet2021
34857756Atlas of RNA editing events affecting protein expression in aged and Alzheimer's disease human brain tissue.Nat Commun2021
34707490Uncovering Disease Mechanisms in a Novel Mouse Model Expressing Humanized APOEε4 and Trem2*R47H.Front Aging Neurosci2021
34366832Comprehensive Evaluation of the 5XFAD Mouse Model for Preclinical Testing Applications: A MODEL-AD Study.Front Aging Neurosci2021
34027015Transfer learning-trained convolutional neural networks identify novel MRI biomarkers of Alzheimer's disease progression.Alzheimers Dement (Amst)2021
33947463Multi-tissue neocortical transcriptome-wide association study implicates 8 genes across 6 genomic loci in Alzheimer's disease.Genome Med2021
32492070Transcriptomic stratification of late-onset Alzheimer's cases reveals novel genetic modifiers of disease pathology.PLoS Genet2020
32047652Brain microRNAs associated with late-life depressive symptoms are also associated with cognitive trajectory and dementia.NPJ Genom Med2020
33172468A novel systems biology approach to evaluate mouse models of late-onset Alzheimer's disease.Mol Neurodegener2020
33283040Model organism development and evaluation for late-onset Alzheimer's disease: MODEL-AD.Alzheimers Dement (N Y)2020
33085189The AD Knowledge Portal: A Repository for Multi-Omic Data on Alzheimer's Disease and Aging.Curr Protoc Hum Genet2020
33188183Molecular estimation of neurodegeneration pseudotime in older brains.Nat Commun2020
33273466Author Correction: Molecular estimation of neurodegeneration pseudotime in older brains.Nat Commun2020
33046718Large eQTL meta-analysis reveals differing patterns between cerebral cortical and cerebellar brain regions.Sci Data2020
32668255Meta-Analysis of the Alzheimer's Disease Human Brain Transcriptome and Functional Dissection in Mouse Models.Cell Rep2020
30962425Large-scale proteomic analysis of human brain identifies proteins associated with cognitive trajectory in advanced age.Nat Commun2019
31510680Identifying and ranking potential driver genes of Alzheimer's disease using multiview evidence aggregation.Bioinformatics2019
29298978A machine learning approach to integrate big data for precision medicine in acute myeloid leukemia.Nat Commun2018
30204156The Mount Sinai cohort of large-scale genomic, transcriptomic and proteomic data in Alzheimer's disease.Sci Data2018
30558641Genome-wide RNAseq study of the molecular mechanisms underlying microglia activation in response to pathological tau perturbation in the rTg4510 tau transgenic animal model.Mol Neurodegener2018
27079753Crowdsourced estimation of cognitive decline and resilience in Alzheimer's disease.Alzheimers Dement2016
27668389Gene expression elucidates functional impact of polygenic risk for schizophrenia.Nat Neurosci2016
27727239Human whole genome genotype and transcriptome data for Alzheimer's and other neurodegenerative diseases.Sci Data2016
27145341Identifying Network Perturbation in Cancer.PLoS Comput Biol2016
27287041Extracting a low-dimensional description of multiple gene expression datasets reveals a potential driver for tumor-associated stroma in ovarian cancer.Genome Med2016
25583238Sparse expression bases in cancer reveal tumor drivers.Nucleic Acids Res2015
25714365SPINE: SParse eIgengene NEtwork linking gene expression clusters in Dehalococcoides mccartyi to perturbations in experimental conditions.PLoS One2015
25415970Rare variation facilitates inferences of fine-scale population structure in humans.Mol Biol Evol2015
24482836A variational Bayes discrete mixture test for rare variant association.Genet Epidemiol2014
23671412Improving breast cancer survival analysis through competition-based multidimensional modeling.PLoS Comput Biol2013
23825936PUMA: a unified framework for penalized multiple regression analysis of GWAS data.PLoS Comput Biol2013
22423221A meta-analysis and genome-wide association study of platelet count and mean platelet volume in african americans.PLoS Genet2012
23103231Imputation of exome sequence variants into population- based samples and blood-cell-trait-associated loci in African Americans: NHLBI GO Exome Sequencing Project.Am J Hum Genet2012
22771729Simultaneously testing for marginal genetic association and gene-environment interaction.Am J Epidemiol2012
22471599Mouse obesity network reconstruction with a variational Bayes algorithm to employ aggressive false positive control.BMC Bioinformatics2012
22563072A novel variational Bayes multiple locus Z-statistic for genome-wide association studies with Bayesian model averaging.Bioinformatics2012
20105321A variational Bayes algorithm for fast and accurate multiple locus genome-wide association analysis.BMC Bioinformatics2010
21152011Gene expression network reconstruction by convex feature selection when incorporating genetic perturbations.PLoS Comput Biol2010
17339224Neutral evolution of multiple quantitative characters: a genealogical approach.Genetics2007
17947430Quantitative trait loci for the circadian clock in Neurospora crassa.Genetics2007
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Collaborators

Lara M Mangravite
Children's Hospital Oakland Research Institute
Co-authored papers 17
Gregory W Carter
Tufts University School of Medicine
Co-authored papers 10
Philip L De Jager
Columbia University Medical Center
Co-authored papers 10
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University of Washington
Co-authored papers 9
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Mayo Clinic
Co-authored papers 7
Christoph Preuss
Universite de Montreal
Co-authored papers 7
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Rush University Medical Center
Co-authored papers 7
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Co-authored papers 7
Eric B Dammer
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Co-authored papers 6
Gareth R Howell
Tufts University Graduate School of Biomedical Sciences
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Mette A Peters
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F. Hoffmann-La Roche Ltd
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Goizueta Alzheimer's Disease Research Center, Emory University School of Medicine
Co-authored papers 6
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Cornell University
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Charles Kooperberg
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Xue Wang
Mayo Clinic
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Gabriel E Hoffman
Center for Disease Neurogenomics, Icahn School of Medicine at Mount Sinai
Co-authored papers 4
Eric E Schadt
Icahn School of Medicine at Mount Sinai
Co-authored papers 4
Bin Zhang
Graduate School of Medicine, The University of Tokyo
Co-authored papers 4
Kristen K Dang
Benaroya Research Institute at Virginia Mason
Co-authored papers 4
Su-In Lee
University of Washington
Co-authored papers 4
James G Wilson
Beth Israel Deaconess Medical Center
Co-authored papers 3
James A Eddy
Benaroya Research Institute at Virginia Mason, Institute for Systems Biology, Sage Bionetworks, University of Illinois at Urbana-Champaign
Co-authored papers 3
Santhi K Ganesh
Co-authored papers 3
James Y Dai
Fred Hutchinson Cancer Center
Co-authored papers 3
Leslie A Lange
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Release 1.2