Author details

Full Name

Gregory J Riggins

Affiliation

ORCID

Career Start Year

1992

Papers

173

H Index

Expertise

CM4AI Collaborator

PMID	Paper Title	Journal Title	Published Year
37144982	TERT and BRAF V600E mutations in thyroid cancer of World Trade Center Responders.		2023
36831670	Mebendazole Treatment Disrupts the Transcriptional Activity of Hypoxia-Inducible Factors 1 and 2 in Breast Cancer Cells.		2023
35118381	Neutrophil depletion enhanced the -NT therapy in mouse and rabbit tumor models.	Neuro-Oncology Advances	2022
36578038	Mebendazole prevents distant organ metastases in part by decreasing ITGÎ²4 expression and cancer stemness.		2022
34298505	Impact of international research fellows in neurosurgery: results from a single academic center.	Journal of Neurosurgery	2022
34987156	Author Correction: Atrx inactivation drives disease-defining phenotypes in glioma cells of origin through global epigenomic remodeling.	Nat Commun	2022
34850159	Evaluation of a DNA demethylating agent in combination with all-trans retinoic acid for IDH1-mutant gliomas.	Neuro-Oncology	2022
34262644	Mebendazole disrupts stromal desmoplasia and tumorigenesis in two models of pancreatic cancer.	Oncotarget	2021
33681764	The glutamine antagonist prodrug JHU-083 slows malignant glioma growth and disrupts mTOR signaling.	Neuro-Oncology Advances	2021
34216463	Evaluation of a procaspase-3 activator with hydroxyurea or temozolomide against high-grade meningioma in cell culture and canine cancer patients.	Neuro Oncol	2021
34157150	Post-9/11 excess risk of thyroid cancer: Surveillance or exposure?	American Journal of Industrial Medicine	2021
31165996	The Small Bowel Cancer Incidence Enigma.	Pathology and Oncology Research	2020
31846433	Mebendazole inhibits tumor growth and prevents lung metastasis in models of advanced thyroid cancer.		2020
32065471	A role for caveola-forming proteins caveolin-1 and CAVIN1 in the pro-invasive response of glioblastoma to osmotic and hydrostatic pressure.	Journal of Cellular and Molecular Medicine	2020
32060379	Matrix protease production, epithelial-to-mesenchymal transition marker expression and invasion of glioblastoma cells in response to osmotic or hydrostatic pressure.	Scientific Reports	2020
31996469	Current Perspectives on Circulating Tumor DNA, Precision Medicine, and Personalized Clinical Management of Cancer.	Mol Cancer Res	2020
33506200	Mebendazole and temozolomide in patients with newly diagnosed high-grade gliomas: results of a phase 1 clinical trial.	Neurooncol Adv	2020
32650362	Preventative Effect of Mebendazole against Malignancies in Neurofibromatosis 1.	Genes	2020
30949900	Correlation of the invasive potential of glioblastoma and expression of caveola-forming proteins caveolin-1 and CAVIN1.	Journal of Neuro-Oncology	2019
30289729	Mutation Profiles in Glioblastoma 3D Oncospheres Modulate Drug Efficacy.	SLAS Technol	2019
30184215	Demethylation and epigenetic modification with 5-azacytidine reduces IDH1 mutant glioma growth in combination with temozolomide.	Neuro Oncol	2019
30808951	G-quadruplex DNA drives genomic instability and represents a targetable molecular abnormality in ATRX-deficient malignant glioma.	Nat Commun	2019
31067756	Molecular Study of Thyroid Cancer in World Trade Center Responders.	Int J Environ Res Public Health	2019
29648826	N-Substituted Prodrugs of Mebendazole Provide Improved Aqueous Solubility and Oral Bioavailability in Mice and Dogs.	Journal of Medicinal Chemistry	2018
30510368	Traps and trumps from adjacent-to-tumor samples in gastric cancer research.	Chin J Cancer Res	2018
30542164	Disruption of aÂ self-amplifying catecholamine loop reduces cytokine release syndrome.	Nature	2018
30296373	Tunable Stability of Imidazotetrazines Leads to a Potent Compound for Glioblastoma.	ACS Chem Biol	2018
30414098	Mebendazole and radiation in combination increase survival through anticancer mechanisms in an intracranial rodent model of malignant meningioma.	Journal of Neuro-Oncology	2018
29535300	Atrx inactivation drives disease-defining phenotypes in glioma cells of origin through global epigenomic remodeling.	Nat Commun	2018
29113289	Synergistic and targeted therapy with a procaspase-3 activator and temozolomide extends survival in glioma rodent models and is feasible for the treatment of canine malignant glioma patients.	Oncotarget	2017
28412733	Prevention of tumor seeding during needle biopsy by chemotherapeutic-releasing gelatin sticks.	Oncotarget	2017
29262640	GEJ cancers: gastric or esophageal tumors? searching for the answer according to molecular identity.	Oncotarget	2017
27824943	Correction: A High-Throughput Screen Identifies 2,9-Diazaspiro[5.5]Undecanes as Inducers of the Endoplasmic Reticulum Stress Response with Cytotoxic Activity in 3D Glioma Cell Models.	PLoS ONE	2016
27028405	Establishment and Biological Characterization of a Panel of Glioblastoma Multiforme (GBM) and GBM Variant Oncosphere Cell Lines.	PLoS One	2016
26626643	Suppression of trophoblast cell surface antigen 2 enhances proliferation and migration in liver fluke-associated cholangiocarcinoma.	Annals of Hepatology	2016
27570969	A High-Throughput Screen Identifies 2,9-Diazaspiro[5.5]Undecanes as Inducers of the Endoplasmic Reticulum Stress Response with Cytotoxic Activity in 3D Glioma Cell Models.	PLoS ONE	2016
27612418	Mebendazole and a non-steroidal anti-inflammatory combine to reduce tumor initiation in a colon cancer preclinical model.	Oncotarget	2016
27843500	Somatic retrotransposition is infrequent in glioblastomas.	Mob DNA	2016
25253417	Effective treatment of diverse medulloblastoma models with mebendazole and its impact on tumor angiogenesis.	Neuro Oncol	2015
25929784	The role of piRNA and its potential clinical implications in cancer.	Epigenomics	2015
25376612	Repurposing the antihelmintic mebendazole as a hedgehog inhibitor.	Mol Cancer Ther	2015
25862759	Brain Penetration and Efficacy of Different Mebendazole Polymorphs in a Mouse Brain Tumor Model.	Clinical Cancer Research	2015
25471051	A model of a patient-derived IDH1 mutant anaplastic astrocytoma with alternative lengthening of telomeres.	J Neurooncol	2015
25849940	Clostridium novyi-NT can cause regression of orthotopically implanted glioblastomas in rats.	Oncotarget	2015
26315676	The anthelmintic drug mebendazole inhibits growth, migration and invasion in gastric cancer cell model.	Toxicology in Vitro	2015
26195750	Detection of tumor-derived DNA in cerebrospinal fluid of patients with primary tumors of the brain and spinal cord.	Proceedings of the National Academy of Sciences of the United States of America	2015
24766300	Antihelminthic benzimidazoles are novel HIF activators that prevent oxidative neuronal death via binding to tubulin.	Antioxidants and Redox Signaling	2015
24553385	Detection of circulating tumor DNA in early- and late-stage human malignancies.	Sci Transl Med	2014
25305755	Somatic mutations of SUZ12 in malignant peripheral nerve sheath tumors.	Nat Genet	2014
26466412	EFFECT OF THE ANTIPARASITIC DRUG MEBENDAZOLE ON CHOLANGIOCARCINOMA GROWTH.	Southeast Asian Journal of Tropical Medicine and Public Health	2014