Author details

Full Name

Aaron R Thorner

Affiliation

ORCID

Career Start Year

2005

Papers

H Index

Expertise

CM4AI Collaborator

PMID	Paper Title	Journal Title	Published Year
36724417	Circulating Tumor DNA Is Prognostic in Intermediate-Risk Rhabdomyosarcoma: A Report From the Children's Oncology Group.	J Clin Oncol	2023
37596911	Loss of heterozygosity does not occur in BRCA1/2 mutant pediatric solid and central nervous system tumors.	Pediatr Blood Cancer	2023
37915591	MUC1-C integrates aerobic glycolysis with suppression of oxidative phosphorylation in triple-negative breast cancer stem cells.		2023
36712079	Somatic mutation but not aneuploidy differentiates lung cancer in never-smokers and smokers.	bioRxiv	2023
37141891	Comprehensive genetic and phenotype analysis of 95 individuals with mosaic tuberous sclerosis complex.		2023
34635572	Sporadic facial angiofibroma and sporadic angiomyolipoma mimicking tuberous sclerosis complex.	Journal of Medical Genetics	2022
35580298	Circulating Tumor DNA as a Biomarker in Patients With Stage III and IV Wilms Tumor: Analysis From a Children's Oncology Group Trial, AREN0533.	Journal of Clinical Oncology	2022
36221002	Adverse prognostic impact of the loss of STAG2 protein expression in patients with newly diagnosed localised Ewing sarcoma: A report from the Children's Oncology Group.	Br J Cancer	2022
35561344	Circulating Tumor DNA Is Associated with Response and Survival in Patients with Advanced Leiomyosarcoma.	Clinical Cancer Research	2022
35358092	Ultrasensitive profiling of UV-induced mutations identifies thousands of subclinical facial tumors in tuberous sclerosis complex.	Journal of Clinical Investigation	2022
34507355	Genomic profiling of a randomized trial of interferon-Î± vs hydroxyurea in MPN reveals mutation-specific responses.	Blood advances	2022
35084050	Implementation of a prostate cancer-specific targeted sequencing panel for credentialing of patient-derived cell lines and genomic characterization of patient samples.	Prostate	2022
34590005	Genomic Evolution in a Patient With Lung Adenocarcinoma With a Germline <i>EGFR</i> T790M Mutation.	JTO Clin Res Rep	2021
33561953	Spatial Heterogeneity in Large Resected Diffuse Large B-Cell Lymphoma Bulks Analysed by Massively Parallel Sequencing of Multiple Synchronous Biopsies.	Cancers	2021
34203201	Dissection of <i>PIK3CA</i> Aberration for Cervical Adenocarcinoma Outcomes.	Cancers (Basel)	2021
33506581	Molecular profiles of response to neoadjuvant chemoradiotherapy in oesophageal cancers to develop personalized treatment strategies.	Mol Oncol	2021
33353975	Correction: Low-level mosaicism in tuberous sclerosis complex: prevalence, clinical features, and risk of disease transmission.	Genet Med	2021
33414136	Molecular Characterization and Therapeutic Targeting of Colorectal Cancers Harboring Receptor Tyrosine Kinase Fusions.	Clin Cancer Res	2021
33399078	Clonal evolution in diffuse large B-cell lymphoma with central nervous system recurrence.	ESMO Open	2021
33268447	Genetic Ancestry Contributes to Somatic Mutations in Lung Cancers from Admixed Latin American Populations.	Cancer Discov	2021
34554931	RAF1 amplification drives a subset of bladder tumors and confers sensitivity to MAPK-directed therapeutics.	J Clin Invest	2021
32587373	Author Correction: Cas9 activates the p53 pathway and selects for p53-inactivating mutations.	Nat Genet	2020
32424350	Cas9 activates the p53 pathway and selects for p53-inactivating mutations.	Nat Genet	2020
32188490	Clinical and molecular characterization of virus-positive and virus-negative Merkel cell carcinoma.	Genome Medicine	2020
32068070	ViroPanel: Hybrid Capture and Massively Parallel Sequencing for Simultaneous Detection and Profiling of Oncogenic Virus Infection and Tumor Genome.	Journal of Molecular Diagnostics	2020
32341571	Plasma cell-free DNA variant analysis compared with methylated DNA analysis in renal cell carcinoma.	Genet Med	2020
32393766	Acquired resistance to combined BET and CDK4/6 inhibition in triple-negative breast cancer.	Nat Commun	2020
32467349	Insulin-Like Growth Factor-1 Receptor Expression and Disease Recurrence and Survival in Patients with Resected Pancreatic Ductal Adenocarcinoma.	Cancer Epidemiol Biomarkers Prev	2020
31653662	Mutations and Response to Rapalogs in Patients with Metastatic Renal Cell Carcinoma.	Mol Cancer Ther	2020
30880335	Correction: Detection of circulating tumour DNA is associated with inferior outcomes in Ewing sarcoma and osteosarcoma: a report from the Children's Oncology Group.	Br J Cancer	2019
31697821	Genomic analyses of PMBL reveal new drivers and mechanisms of sensitivity to PD-1 blockade.	Blood	2019
31585941	A Comprehensive PDX Gastric Cancer Collection Captures Cancer Cell-Intrinsic Transcriptional MSI Traits.	Cancer Res	2019
31816062	Genomic analyses of flow-sorted Hodgkin Reed-Sternberg cells reveal complementary mechanisms of immune evasion.	Blood Adv	2019
29961768	Germline cancer susceptibility gene variants, somatic second hits, and survival outcomes in patients with resected pancreatic cancer.	Genet Med	2019
31273045	Generalised mosaicism for mutation in isolated lymphangioleiomyomatosis.	European Respiratory Journal	2019
30793095	Detection of Circulating Tumor DNA in Patients With Leiomyosarcoma With Progressive Disease.	JCO Precision Oncology	2019
31160751	Low-level mosaicism in tuberous sclerosis complex: prevalence, clinical features, and risk of disease transmission.	Genet Med	2019
29789628	Targetable vulnerabilities in T- and NK-cell lymphomas identified through preclinical models.	Nat Commun	2018
28978556	Genomic Heterogeneity as a Barrier to Precision Medicine in Gastroesophageal Adenocarcinoma.	Cancer Discov	2018
30027144	Detection of Somatic Structural Variants Enables Quantification and Characterization of Circulating Tumor DNA in Children With Solid Tumors.	JCO Precis Oncol	2018
30153220	Characterization of the Neuroendocrine Tumor Immune Microenvironment.	Pancreas	2018
29955181	Publisher Correction: Molecular subtypes of diffuse large B cell lymphoma are associated with distinct pathogenic mechanisms and outcomes.	Nat Med	2018
29955182	Author Correction: Molecular subtypes of diffuse large B cell lymphoma are associated with distinct pathogenic mechanisms and outcomes.	Nat Med	2018
30089904	Genetic and transcriptional evolution alters cancer cell line drug response.	Nature	2018
30131550	Detection of circulating tumour DNA is associated with inferior outcomes in Ewing sarcoma and osteosarcoma: a report from the Children's Oncology Group.	Br J Cancer	2018
29098284	Association of Alterations in Main Driver Genes With Outcomes of Patients With Resected Pancreatic Ductal Adenocarcinoma.	JAMA Oncol	2018
29310587	Unique, dual-indexed sequencing adapters with UMIs effectively eliminate index cross-talk and significantly improve sensitivity of massively parallel sequencing.	BMC Genomics	2018
29713087	Molecular subtypes of diffuse large B cell lymphoma are associated with distinct pathogenic mechanisms and outcomes.	Nat Med	2018
29477794	Clonal evolution and heterogeneity in metastatic head and neck cancer-An analysis of the Austrian Study Group of Medical Tumour Therapy study group.	European Journal of Cancer	2018
29608884	Detection of Mutations in Barrett's Esophagus Before Progression to High-Grade Dysplasia or Adenocarcinoma.	Gastroenterology	2018