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Author Details

Janine H Santos
National Institute of Environmental Health Sciences
1992
52
30
Trey Ideker (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
36117466Photochemical Targeting of Mitochondria to Overcome Chemoresistance in Ovarian Cancer [â¿ ].Photochem Photobiol2023
37174030Methods to Evaluate Changes in Mitochondrial Structure and Function in Cancer.Cancers (Basel)2023
37431815Answer to Gerber et al. "Autosomal recessive pathogenic MSTO1 variants in hereditary optic atrophy".EMBO Mol Med2023
34936503Mitochondrial DNA damage as driver of cellular outcomes.Am J Physiol Cell Physiol2022
35453445NRF2 Alters Mitochondrial Gene Expression in Neonate Mice Exposed to Hyperoxia.Antioxidants (Basel)2022
35930448Emerging mitochondrial signaling mechanisms in cardio-oncology: beyond oxidative stress.Am J Physiol Heart Circ Physiol2022
33271282Mitochondria signaling to the epigenome: A novel role for an old organelle.Free Radic Biol Med2021
34819359Correction: A brain-specific PGC1a fusion transcript affects gene expression and behavioral outcomes in mice.Life Sci Alliance2021
34649938A brain-specific <i>pgc1</i>α fusion transcript affects gene expression and behavioural outcomes in mice.Life Sci Alliance2021
32937126Single Nucleotide Resolution Analysis Reveals Pervasive, Long-Lasting DNA Methylation Changes by Developmental Exposure to a Mitochondrial Toxicant.Cell Rep2020
31923552Locus coeruleus neurons are most sensitive to chronic neuroinflammation-induced neurodegeneration.Brain Behav Immun2020
31110224Mitochondrial Oxidative Phosphorylation defect in the Heart of Subjects with Coronary Artery Disease.Sci Rep2019
30737248Mitochondrial acetyl-CoA reversibly regulates locus-specific histone acetylation and gene expression.Life Sci Alliance2019
30917518Telomerase Impinges on the Cellular Response to Oxidative Stress Through Mitochondrial ROS-Mediated Regulation of Autophagy.Int J Mol Sci2019
29398562Switch of Mitochondrial Superoxide Dismutase into a Prooxidant Peroxidase in Manganese-Deficient Cells and Mice.Cell Chem Biol2018
29868123A Leveraged Signal-to-Noise Ratio (LSTNR) Method to Extract Differentially Expressed Genes and Multivariate Patterns of Expression From Noisy and Low-Replication RNAseq Data.Front Genet2018
29668680Mitochondrial nicotinamide adenine dinucleotide reduced (NADH) oxidation links the tricarboxylic acid (TCA) cycle with methionine metabolism and nuclear DNA methylation.PLoS Biol2018
26725009TCA Cycle and Mitochondrial Membrane Potential Are Necessary for Diverse Biological Functions.Mol Cell2016
27415830A Novel Analytical Strategy to Identify Fusion Transcripts between Repetitive Elements and Protein Coding-Exons Using RNA-Seq.PLoS One2016
27019630Hyperglycemia Differentially Affects Maternal and Fetal DNA Integrity and DNA Damage Response.Int J Biol Sci2016
26935406Menadione-Induced DNA Damage Leads to Mitochondrial Dysfunction and Fragmentation During Rosette Formation in Fuchs Endothelial Corneal Dystrophy.Antioxid Redox Signal2016
26699654Critical Role for Telomerase in the Mechanism of Flow-Mediated Dilation in the Human Microcirculation.Circ Res2016
25651975MnSOD upregulation sustains the Warburg effect via mitochondrial ROS and AMPK-dependent signalling in cancer.Nat Commun2015
24342190Intrinsic mitochondrial DNA repair defects in Ataxia Telangiectasia.DNA Repair (Amst)2014
25197655DNA damage and its cellular response in mother and fetus exposed to hyperglycemic environment.Biomed Res Int2014
25127496Mitochondria, energetics, epigenetics, and cellular responses to stress.Environ Health Perspect2014
24623245Quantitative PCR-based measurement of nuclear and mitochondrial DNA damage and repair in mammalian cells.Methods Mol Biol2014
22982047The peroxidase activity of mitochondrial superoxide dismutase.Free Radic Biol Med2013
21937513Human telomerase acts as a hTR-independent reverse transcriptase in mitochondria.Nucleic Acids Res2012
23020852Mitochondria and telomeres: the promiscuous roles of TIN2.Mol Cell2012
22056359Mitochondrial genome instability and ROS enhance intestinal tumorigenesis in APC(Min/+) mice.Am J Pathol2012
20089117A mutant telomerase defective in nuclear-cytoplasmic shuttling fails to immortalize cells and is associated with mitochondrial dysfunction.Aging Cell2010
21109199Targeted expression of catalase to mitochondria prevents age-associated reductions in mitochondrial function and insulin resistance.Cell Metab2010
20936168The emerging role of telomerase reverse transcriptase in mitochondrial DNA metabolism.J Nucleic Acids2010
20520826Expression of (NES-)hTERT in cancer cells delays cell cycle progression and increases sensitivity to genotoxic stress.PLoS One2010
19582765Analysis of oxidative damage by gene-specific quantitative PCR.Curr Protoc Hum Genet2009
16395692Mitochondrial toxicity in hearts of CD-1 mice following perinatal exposure to AZT, 3TC, or AZT/3TC in combination.Environ Mol Mutagen2007
17420247Roles for the human ATP-dependent Lon protease in mitochondrial DNA maintenance.J Biol Chem2007
15878696Role of mitochondrial DNA in toxic responses to oxidative stress.DNA Repair (Amst)2006
16673882Quantitative PCR-based measurement of nuclear and mitochondrial DNA damage and repair in mammalian cells.Methods Mol Biol2006
16613901Mitochondrial localization of telomerase as a determinant for hydrogen peroxide-induced mitochondrial DNA damage and apoptosis.Hum Mol Genet2006
16368709Mitochondrial and nuclear DNA defects in Saccharomyces cerevisiae with mutations in DNA polymerase gamma associated with progressive external ophthalmoplegia.Hum Mol Genet2006
15569357Mitochondrial hTERT exacerbates free-radical-mediated mtDNA damage.Aging Cell2004
12424245Cell sorting experiments link persistent mitochondrial DNA damage with loss of mitochondrial membrane potential and apoptotic cell death.J Biol Chem2003
14556849Vanadium-induced STAT-1 activation in lung myofibroblasts requires H2O2 and P38 MAP kinase.Free Radic Biol Med2003
14570713Reduction in frataxin causes progressive accumulation of mitochondrial damage.Hum Mol Genet2003
12676768Vanadium-induced HB-EGF expression in human lung fibroblasts is oxidant dependent and requires MAP kinases.Am J Physiol Lung Cell Mol Physiol2003
12013794Measuring oxidative mtDNA damage and repair using quantitative PCR.Methods Mol Biol2002
12427535Mitochondrial DNA repair and aging.Mutat Res2002
10521675The synergistic effects of vanillin on recombination predominate over its antimutagenic action in relation to MMC-induced lesions in somatic cells of Drosophila melanogaster.Mutat Res1999
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Collaborators

Bennett Van Houten
UPMC-Hillman Cancer Center, University of Pittsburgh
Co-authored papers 14
Tianyuan Wang
National Institute of Environmental Health Sciences, National Institutes of Health
Co-authored papers 7
Joel N Meyer
Duke University Nicholas School of the Environment.
Co-authored papers 6
William C Copeland
National Institute of Environmental Health Sciences, National Institutes of Health
Co-authored papers 4
Gerald S Shadel
Salk Institute for Biological Studies
Co-authored papers 3
David D Gutterman
Co-authored papers 2
Thomas J Begley
University at Albany
Co-authored papers 1
George A Porter
Co-authored papers 1
Frederick E Domann
University of Iowa
Co-authored papers 1
Brooke E Christian
Appalachian State University
Co-authored papers 1
Scott J Bultman
Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill
Co-authored papers 1
Jianying Li
Co-authored papers 1
Daniel T Shaughnessy
National Institute of Environmental Health Sciences, National Institutes of Health
Co-authored papers 1
Andrea A Baccarelli
Mailman School of Public Health, Columbia University
Co-authored papers 1
Robert W Sobol
University of South Alabama
Co-authored papers 1
Jian Feng
Co-authored papers 1
Kimberly A McAllister
Queen's University
Co-authored papers 1
Pierre R Bushel
Co-authored papers 1
Leroy Worth
University Children's Hospital Regensburg (KUNO)
Co-authored papers 1
Tong Liu
Co-authored papers 1
Matthew D Hirschey
Duke Molecular Physiology Institute, Duke University School of Medicine
Co-authored papers 1
Frederick L Tyson
National Institute of Environmental Health Sciences
Co-authored papers 1
Peter S Rabinovitch
Co-authored papers 1
Raymond R Tice
National Institute of Environmental Health Sciences
Co-authored papers 1
Astrid C Haugen
National Institute of Environmental Health Sciences
Co-authored papers 1
David M Balshaw
National Institute of Environmental Health Sciences, National Institutes of Health
Co-authored papers 1
Yingming Zhao
Co-authored papers 1
Kristine L Witt
National Institute of Environmental Health Sciences/National Institutes of Health
Co-authored papers 1
Raul Mostoslavsky
Center for Cancer Research, Massachusetts General Hospital, Harvard Medical School
Co-authored papers 1
Trey Ideker (CM4AI)
University of California San Diego
Co-authored papers 1
Release 1.2