Author details

Full Name

Kamel Khalili

Affiliation

ORCID

Career Start Year

1983

Papers

460

H Index

Expertise

CM4AI Collaborator

PMID	Paper Title	Journal Title	Published Year
37547075	Bag3 Regulates Mitochondrial Function and the Inflammasome Through Canonical and Noncanonical Pathways inÂ the Heart.		2023
37587230	Preclinical safety and biodistribution of CRISPR targeting SIV in non-human primates.		2023
37815117	Lipid nanocarrier targeting activated macrophages for antiretroviral therapy of HIV reservoir.		2023
37886577	HIV-1 mRNA Knockdown with CRISPR/Cas9 Enhances Neurocognitive Function.		2023
37346975	Strategic self-limiting production of infectious HIV particles by CRISPR in permissive cells.		2023
37126704	CRISPR editing of CCR5 and HIV-1 facilitates viral elimination in antiretroviral drug-suppressed virus-infected humanized mice.		2023
36077131	Protein Quality Control in Glioblastoma: A Review of the Current Literature with New Perspectives on Therapeutic Targets.	International Journal of Molecular Sciences	2022
33863814	Elevated Asparagine Biosynthesis Drives Brain Tumor Stem Cell Metabolic Plasticity and Resistance to Oxidative Stress.	Mol Cancer Res	2021
33472174	PAM (PIK3/AKT/mTOR) signaling in glia: potential contributions to brain tumors in aging.	Aging	2021
33771978	Neuromodulation of BAG co-chaperones by HIV-1 viral proteins and HO: implications for HIV-associated neurological disorders.	Cell Death Discovery	2021
34033088	Fetal Brain Injury Models of Fetal Alcohol Syndrome: Examination of Neuronal Morphologic Condition Using Sholl Assay.	Methods in Molecular Biology	2021
34033084	Compartmentalized Neuronal Cultures.	Methods in Molecular Biology	2021
34033077	Isolation and Propagation of Primary Human and Rodent Embryonic Neural Progenitor Cells and Cortical Neurons.	Methods in Molecular Biology	2021
33499370	Induction of Brain Tumors by the Archetype Strain of Human Neurotropic JCPyV in a Transgenic Mouse Model.	Viruses	2021
33065212	Cross-talk between lipid homeostasis and endoplasmic reticulum stress in neurodegeneration: Insights for HIV-1 associated neurocognitive disorders (HAND).	Neurochemistry International	2020
32117811	Amplification of Replication Competent HIV-1 by Adoptive Transfer of Human Cells From Infected Humanized Mice.	Frontiers in Cellular and Infection Microbiology	2020
31556109	Age-related neurodegenerative diseases.	Journal of Cellular Physiology	2020
33247091	CRISPR based editing of SIV proviral DNA in ART treated non-human primates.	Nature Communications	2020
33033233	The lncRNA LOC102549805 (U1) modulates neurotoxicity of HIV-1 Tat protein.	Cell Death and Disease	2020
33074235	Potential Role for Herpesviruses in Alzheimer's Disease.	Journal of Alzheimer's Disease	2020
32956817	Novel BAG3 Variants in African American Patients With Cardiomyopathy: Reduced Î²-Adrenergic Responsiveness in Excitation-Contraction.	Journal of Cardiac Failure	2020
30932190	Evidence for the impact of BAG3 on electrophysiological activity of primary culture of neonatal cardiomyocytes.	Journal of Cellular Physiology	2019
31653397	Suppression of Zika Virus Infection in the Brain by the Antiretroviral Drug Rilpivirine.	Molecular Therapy	2019
35021482	MRI-Guided, Noninvasive Delivery of Magneto-Electric Drug Nanocarriers to the Brain in a Nonhuman Primate.	ACS Applied Bio Materials	2019
30256393	Mitochondrial dysfunction in human immunodeficiency virus-1 transgenic mouse cardiac myocytes.	Journal of Cellular Physiology	2019
30417391	Mitochondrial quality control in cardiac cells: Mechanisms and role in cardiac cell injury and disease.	Journal of Cellular Physiology	2019
30631036	Lamin B is a target for selective nuclear PQC by BAG3: implication for nuclear envelopathies.	Cell Death and Disease	2019
31266936	Sequential LASER ART and CRISPR Treatments Eliminate HIV-1 in a Subset of Infected Humanized Mice.	Nature Communications	2019
30850620	Magnetically guided non-invasive CRISPR-Cas9/gRNA delivery across blood-brain barrier to eradicate latent HIV-1 infection.	Scientific Reports	2019
31209204	Perturbation of synapsins homeostasis through HIV-1 Tat-mediated suppression of BAG3 in primary neuronal cells.	Cell Death and Disease	2019
31114002	Role of Bcl2-associated Athanogene 3 in Turnover of Gap Junction Protein, Connexin 43, in Neonatal Cardiomyocytes.	Scientific Reports	2019
31362387	An Omics Approach to Extracellular Vesicles from HIV-1 Infected Cells.	Cells	2019
30660756	Surface-engineered multimodal magnetic nanoparticles to manage CNS diseases.	Drug Discovery Today	2019
29323723	Haplo-insufficiency of Bcl2-associated athanogene 3 in mice results in progressive left ventricular dysfunction, Î²-adrenergic insensitivity, and increased apoptosis.	Journal of Cellular Physiology	2018
28493473	Dysregulation of mitochondrial bioenergetics and quality control by HIV-1 Tat in cardiomyocytes.	Journal of Cellular Physiology	2018
30548022	Toward the Cure of HIV-1 Infection: Lessons Learned and Yet to be Learned as New Strategies are Developed.	AIDS Reviews	2018
29968495	Broad-Spectrum and Personalized Guide RNAs for CRISPR/Cas9 HIV-1 Therapeutics.	AIDS Res Hum Retroviruses	2018
30390000	Dysregulation of Neuronal Cholesterol Homeostasis upon Exposure to HIV-1 Tat and Cocaine Revealed by RNA-Sequencing.	Scientific Reports	2018
30195766	Removal of HIV DNA by CRISPR from Patient Blood Engrafts in Humanized Mice.	Molecular Therapy - Nucleic Acids	2018
30140897	Association of Variants in BAG3 With Cardiomyopathy Outcomes in African American Individuals.	JAMA Cardiol	2018
30619107	Gene Editing of HIV-1 Co-receptors to Prevent and/or Cure Virus Infection.	Front Microbiol	2018
29938246	The Multifunctional Protein BAG3: A Novel Therapeutic Target in Cardiovascular Disease.	JACC: Basic to Translational Science	2018
29206302	Network analysis of hippocampal neurons by microelectrode array in the presence of HIV-1 Tat and cocaine.	Journal of Cellular Physiology	2018
29549313	Astrocytic metabolic switch is a novel etiology for Cocaine and HIV-1 Tat-mediated neurotoxicity.	Cell Death and Disease	2018
28079886	HIV-1 Nef is released in extracellular vesicles derived from astrocytes: evidence for Nef-mediated neurotoxicity.	Cell Death and Disease	2017
28819214	HIV-1 Nef-induced cardiotoxicity through dysregulation of autophagy.	Scientific Reports	2017
28460414	CRISPR Editing Technology in Biological and Biomedical Investigation.	Journal of Cellular Biochemistry	2017
28366764	InÂ Vivo Excision of HIV-1 Provirus by saCas9 and Multiplex Single-Guide RNAs in Animal Models.	Molecular Therapy	2017
28611130	Precision Medicine for Heart Failure: Lessons From Oncology.	Circulation: Heart Failure	2017
27381181	Evidence for the Role of BAG3 in Mitochondrial Quality Control in Cardiomyocytes.	Journal of Cellular Physiology	2017