| 36862005 | MicroRNA 483-3p overexpression unleashes invasive growth of metastatic colorectal cancer via NDRG1 downregulation and ensuing activation of the ERBB3/AKT axis. | Mol Oncol | 2023 |
| 37585503 | Phosphoproteomics of patient-derived xenografts identifies targets and markers associated with sensitivity and resistance to EGFR blockade in colorectal cancer. | Sci Transl Med | 2023 |
| 37189167 | Multi-label transcriptional classification of colorectal cancer reflects tumor cell population heterogeneity. | Genome Med | 2023 |
| 37079732 | CONNECTOR, fitting and clustering of longitudinal data to reveal a new risk stratification system. | Bioinformatics | 2023 |
| 37063647 | EGAsubmitter: A software to automate submission of nucleic acid sequencing data to the European Genome-phenome Archive. | Front Bioinform | 2023 |
| 36697438 | An mTOR feedback loop mediates the 'flare' ('rebound') response to MET tyrosine kinase inhibition. | Sci Rep | 2023 |
| 36622698 | Synthetic Lethal Interaction with BCL-XL Blockade Deepens Response to Cetuximab in Patient-Derived Models of Metastatic Colorectal Cancer. | Clin Cancer Res | 2023 |
| 36759506 | Colorectal cancer patient-derived organoids and cell lines harboring ATRX and/or DAXX mutations lack Alternative Lengthening of Telomeres (ALT). | Cell Death Dis | 2023 |
| 34635836 | Chromatin Velocity reveals epigenetic dynamics by single-cell profiling of heterochromatin and euchromatin. | Nat Biotechnol | 2022 |
| 36332574 | Dynamic and adaptive cancer stem cell population admixture in colorectal neoplasia. | Cell Stem Cell | 2022 |
| 35931031 | Dynamic and adaptive cancer stem cell population admixture in colorectal neoplasia. | Cell Stem Cell | 2022 |
| 36151307 | Towards precision oncology with patient-derived xenografts. | Nat Rev Clin Oncol | 2022 |
| 35240232 | TRF2 cooperates with CTCF for controlling the oncomiR-193b-3p in colorectal cancer. | Cancer Lett | 2022 |
| 35197630 | Effective drug combinations in breast, colon and pancreatic cancer cells. | Nature | 2022 |
| 34359705 | Synthetic Lethality Screening Highlights Colorectal Cancer Vulnerability to Concomitant Blockade of NEDD8 and EGFR Pathways. | Cancers (Basel) | 2021 |
| 33795873 | Quantifying single-cell ERK dynamics in colorectal cancer organoids reveals EGFR as an amplifier of oncogenic MAPK pathway signalling. | Nat Cell Biol | 2021 |
| 33820776 | Rational Treatment of Metastatic Colorectal Cancer: A Reverse Tale of Men, Mice, and Culture Dishes. | Cancer Discov | 2021 |
| 33864051 | Precision oncology in metastatic colorectal cancer - from biology to medicine. | Nat Rev Clin Oncol | 2021 |
| 34426441 | Molecular Subtyping Combined with Biological Pathway Analyses to Study Regorafenib Response in Clinically Relevant Mouse Models of Colorectal Cancer. | Clin Cancer Res | 2021 |
| 34133926 | The heme synthesis-export system regulates the tricarboxylic acid cycle flux and oxidative phosphorylation. | Cell Rep | 2021 |
| 34344756 | The gRASs Is Greener: Potential New Therapies in Lung Cancer with Acquired Resistance to KRAS<sup>G12C</sup> Inhibitors. | Cancer Discov | 2021 |
| 32430388 | EGFR Blockade Reverts Resistance to KRAS<sup>G12C</sup> Inhibition in Colorectal Cancer. | Cancer Discov | 2020 |
| 33066609 | Implementing Systems Modelling and Molecular Imaging to Predict the Efficacy of BCL-2 Inhibition in Colorectal Cancer Patient-Derived Xenograft Models. | Cancers (Basel) | 2020 |
| 32919890 | Long-term Clinical Outcome of Trastuzumab and Lapatinib for HER2-positive Metastatic Colorectal Cancer. | Clin Colorectal Cancer | 2020 |
| 32578942 | Innovations, challenges, and minimal information for standardization of humanized mice. | EMBO Mol Med | 2020 |
| 33015526 | Intratumoral Transcriptome Heterogeneity Is Associated With Patient Prognosis and Sidedness in Patients With Colorectal Cancer Treated With Anti-EGFR Therapy From the CO.20 Trial. | JCO Precis Oncol | 2020 |
| 32759276 | Colorectal cancer residual disease at maximal response to EGFR blockade displays a druggable Paneth cell-like phenotype. | Sci Transl Med | 2020 |
| 32988996 | Pertuzumab and trastuzumab emtansine in patients with HER2-amplified metastatic colorectal cancer: the phase II HERACLES-B trial. | ESMO Open | 2020 |
| 32700762 | Systems analysis of protein signatures predicting cetuximab responses in KRAS, NRAS, BRAF and PIK3CA wild-type patient-derived xenograft models of metastatic colorectal cancer. | Int J Cancer | 2020 |
| 32183295 | Vitamin C Restricts the Emergence of Acquired Resistance to EGFR-Targeted Therapies in Colorectal Cancer. | Cancers (Basel) | 2020 |
| 31164152 | Combined blockade of MEK and PI3KCA as an effective antitumor strategy in HER2 gene amplified human colorectal cancer models. | J Exp Clin Cancer Res | 2019 |
| 31813455 | Immunogenomics of Colorectal Tumors: Facts and Hypotheses on an Evolving Saga. | Trends Cancer | 2019 |
| 31699882 | Adaptive mutability of colorectal cancers in response to targeted therapies. | Science | 2019 |
| 31375513 | Patient-Derived Xenografts and Matched Cell Lines Identify Pharmacogenomic Vulnerabilities in Colorectal Cancer. | Clin Cancer Res | 2019 |
| 31287988 | The Stromal and Immune Landscape of Colorectal Cancer Progression during Anti-EGFR Therapy. | Cancer Cell | 2019 |
| 31253177 | Evolving neoantigen profiles in colorectal cancers with DNA repair defects. | Genome Med | 2019 |
| 31126969 | INKA, an integrative data analysis pipeline for phosphoproteomic inference of active kinases. | Mol Syst Biol | 2019 |
| 30952821 | HER2 Positivity Predicts Unresponsiveness to EGFR-Targeted Treatment in Metastatic Colorectal Cancer. | Oncologist | 2019 |
| 30808777 | Plasma HER2 (<i>ERBB2</i>) Copy Number Predicts Response to HER2-targeted Therapy in Metastatic Colorectal Cancer. | Clin Cancer Res | 2019 |
| 30979792 | INKA, an integrative data analysis pipeline for phosphoproteomic inference of active kinases. | Mol Syst Biol | 2019 |
| 30971826 | Prioritization of cancer therapeutic targets using CRISPR-Cas9 screens. | Nature | 2019 |
| 28974546 | A Molecularly Annotated Model of Patient-Derived Colon Cancer Stem-Like Cells to Assess Genetic and Nongenetic Mechanisms of Resistance to Anti-EGFR Therapy. | Clin Cancer Res | 2018 |
| 29990497 | Radiologic and Genomic Evolution of Individual Metastases during HER2 Blockade in Colorectal Cancer. | Cancer Cell | 2018 |
| 29674709 | Known and novel roles of the MET oncogene in cancer: a coherent approach to targeted therapy. | Nat Rev Cancer | 2018 |
| 29659677 | Targeting the human epidermal growth factor receptor 2 (HER2) oncogene in colorectal cancer. | Ann Oncol | 2018 |
| 29538669 | RET fusions in a small subset of advanced colorectal cancers at risk of being neglected. | Ann Oncol | 2018 |
| 28561063 | Selective analysis of cancer-cell intrinsic transcriptional traits defines novel clinically relevant subtypes of colorectal cancer. | Nat Commun | 2017 |
| 28104906 | Interrogating open issues in cancer precision medicine with patient-derived xenografts. | Nat Rev Cancer | 2017 |
| 29092942 | PDX-MI: Minimal Information for Patient-Derived Tumor Xenograft Models. | Cancer Res | 2017 |
| 28912576 | Interrogating open issues in cancer medicine with patient-derived xenografts. | Nat Rev Cancer | 2017 |