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Author Details

Helen H??kansson
Institute of Environmental Medicine, Karolinska Institutet
1976
113
38
PMIDPaper TitleJournal TitlePublished Year
34560258Dose-dependent toxicological effects in rats following a 90-day dietary exposure to PCB-156 include retinoid disruption.Reprod Toxicol2022
34774707Role of retinoids in biology and toxicology.Reprod Toxicol2022
34363983Bone toxicity induced by 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) and the retinoid system: A causality analysis anchored in osteoblast gene expression and mouse data.Reprod Toxicol2021
33607186Role of aryl hydrocarbon receptor (AHR) in overall retinoid metabolism: Response comparisons to 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) exposure between wild-type and AHR knockout mice.Reprod Toxicol2021
33992733Endocrine, metabolic and apical effects of in utero and lactational exposure to non-dioxin-like 2,2',3,4,4',5,5'-heptachlorobiphenyl (PCB 180): A postnatal follow-up study in rats.Reprod Toxicol2021
33965534Effects of a high-fat diet and global aryl hydrocarbon receptor deficiency on energy balance and liver retinoid status in male Sprague-Dawley rats.J Nutr Biochem2021
32171711Regulatory needs and activities to address the retinoid system in the context of endocrine disruption: The European viewpoint.Reprod Toxicol2020
30929029Report from the BfR expert hearing on practicability of hormonal measurements: recommendations for experimental design of toxicological studies with integrated hormonal end points.Arch Toxicol2019
30880216Gender- and dose-related metabolome alterations in rat offspring after in utero and lactational exposure to PCB 180.Toxicol Appl Pharmacol2019
27714423Scientific principles for the identification of endocrine-disrupting chemicals: a consensus statement.Arch Toxicol2017
28433708Toxicological characterisation of two novel selective aryl hydrocarbon receptor modulators in Sprague-Dawley rats.Toxicol Appl Pharmacol2017
28957439Skeletal and dental effects on rats following in utero/lactational exposure to the non-dioxin-like polychlorinated biphenyl PCB 180.PLoS One2017
25827101Programming of metabolic effects in C57BL/6JxFVB mice by in utero and lactational exposure to perfluorooctanoic acid.Arch Toxicol2016
27343956The European Registered Toxicologist (ERT): Current status and prospects for advancement.Toxicol Lett2016
27068293Effects of developmental exposure to perfluorooctanoic acid (PFOA) on long bone morphology and bone cell differentiation.Toxicol Appl Pharmacol2016
25795401Inhibitory effects on osteoblast differentiation in vitro by the polychlorinated biphenyl mixture Aroclor 1254 are mainly associated with the dioxin-like constituents.Toxicol In Vitro2015
26320568In utero/lactational and adult exposures to 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) show differential effects on craniofacial development and growth in rats.Toxicology2015
24588224In utero and lactational exposure to a mixture of environmental contaminants detected in Canadian Arctic human populations alters retinoid levels in rat offspring with low margins of exposure.J Toxicol Environ Health A2014
28962383Craniofacial form is altered by chronic adult exposure to 2,3,7,8-tetrachlorodibenzo-<i>p</i>-dioxin (TCDD) in Han/Wistar and Long-Evans rats with different aryl hydrocarbon receptor (AhR) structures.Toxicol Rep2014
25137063Toxicological profile of ultrapure 2,2',3,4,4',5,5'-heptachlorbiphenyl (PCB 180) in adult rats.PLoS One2014
24887809Gestational and lactational exposure to the polychlorinated biphenyl mixture Aroclor 1254 modulates retinoid homeostasis in rat offspring.Toxicol Lett2014
22781580Harmonization of description and classification of fetal observations: achievements and problems still unresolved: report of the 7th Workshop on the Terminology in Developmental Toxicology Berlin, 4-6 May 2011.Reprod Toxicol2013
24035824New insights to the role of aryl hydrocarbon receptor in bone phenotype and in dioxin-induced modulation of bone microarchitecture and material properties.Toxicol Appl Pharmacol2013
23792420Cumulative health risk assessment of 17 perfluoroalkylated and polyfluoroalkylated substances (PFASs) in the Swedish population.Environ Int2013
23435065Individual breast milk consumption and exposure to PCBs and PCDD/Fs in Hungarian infants: a time-course analysis of the first three months of lactation.Sci Total Environ2013
23360570Establishment of the cumulative margin of exposure for a group of polychlorinated biphenyl (PCB) congeners using an improved approach that accounts for both variability and uncertainty.Regul Toxicol Pharmacol2013
22314386Cadmium-induced effects on cellular signaling pathways in the liver of transgenic estrogen reporter mice.Toxicol Sci2012
22733407The point of transition on the dose-effect curve as a reference point in the evaluation of in vitro toxicity data.J Appl Toxicol2012
21195146Estrogen-like effects of diet-derived cadmium differ from those of orally administered CdCl(2) in the ERE-luc estrogen reporter mouse model.Toxicol Lett2011
22031662Retinol may counteract the negative effect of cadmium on bone.J Nutr2011
21807577Retinoic acid drives aryl hydrocarbon receptor expression and is instrumental to dioxin-induced toxicity during palate development.Environ Health Perspect2011
21830859Perinatal exposure to environmental contaminants detected in Canadian Arctic human populations changes bone geometry and biomechanical properties in rat offspring.J Toxicol Environ Health A2011
21856390In utero and lactational exposure to Aroclor 1254 affects bone geometry, mineral density and biomechanical properties of rat offspring.Toxicol Lett2011
21673325Cerebellum proteomics addressing the cognitive deficit of rats perinatally exposed to the food-relevant polychlorinated biphenyl 138.Toxicol Sci2011
21458519Hepatic effects of a highly purified 2,2',3,4,4',5,5'-heptachlorbiphenyl (PCB 180) in male and female rats.Toxicology2011
19931376Risk to all or none? A comparative analysis of controversies in the health risk assessment of Bisphenol A.Reprod Toxicol2010
20830323A probabilistic approach for estimating infant exposure to environmental pollutants in human breast milk.J Environ Monit2010
20447676Toxicity of Bromkal 70-5DE, a technical mixture of polybrominated diphenyl ethers, following 28 d of oral exposure in rats and impact of analysed impurities.Chemosphere2010
20525538Estrogen-like effects of cadmium in vivo do not appear to be mediated via the classical estrogen receptor transcriptional pathway.Environ Health Perspect2010
20656018Tissue distribution of (35)S-labelled perfluorooctane sulfonate (PFOS) in C57Bl/6 mice following late gestational exposure.Reprod Toxicol2010
20132933Effects of 2,3,7,8-tetrachlorodibenzo-p-dioxin exposure on bone material properties.J Biomech2010
20138101Quantitative and statistical analysis of differences in sensitivity between Long-Evans and Han/Wistar rats following long-term exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin.Regul Toxicol Pharmacol2010
20403408Quantitative characterization of changes in bone geometry, mineral density and biomechanical properties in two rat strains with different Ah-receptor structures after long-term exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin.Toxicology2010
19201780Dioxin-sensitive proteins in differentiating osteoblasts: effects on bone formation in vitro.Toxicol Sci2009
19577634A CASCADE of effects of bisphenol A.Reprod Toxicol2009
19490107The endogenous retinoid metabolite S-4-oxo-9-cis-13,14-dihydro-retinoic acid activates retinoic acid receptor signalling both in vitro and in vivo.FEBS J2009
19500631Health risk assessment procedures for endocrine disrupting compounds within different regulatory frameworks in the European Union.Regul Toxicol Pharmacol2009
19118610Endocrine effects of hexabromocyclododecane (HBCD) in a one-generation reproduction study in Wistar rats.Toxicol Lett2009
18080900Toxicological effects of in utero and lactational exposure of rats to a mixture of environmental contaminants detected in Canadian Arctic human populations.J Toxicol Environ Health A2008
18789370Exposure to dioxin-like pollutants via different food commodities in Swedish children and young adults.Food Chem Toxicol2008
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Collaborators

School of Pharmacy (Toxicology), University of Eastern Finland
Co-authored papers 22
Finnish Institute for Health and Welfare
Co-authored papers 11
VTT Technical Research Centre of Finland Ltd.
Co-authored papers 5
Biomedicine Discovery Institute, Monash University
Co-authored papers 5
Department of Food Hygiene and Environmental Health, University of Helsinki
Co-authored papers 5
Institut des Biomolecules Max Mousseron (IBMM), UMR-CNRS 7, Universite Montpellier
Co-authored papers 4
Istituto di Ricerche Farmacologiche Mario Negri IRCCS
Co-authored papers 3
Finnish Institute for Health and Welfare (THL)
Co-authored papers 3
IRCCS-Istituto di Ricerche Farmacologiche Mario Negri
Co-authored papers 3
Sapienza University of Rome
Co-authored papers 2
University of Helsinki
Co-authored papers 2
Joint Research Centre (JRC)
Co-authored papers 2
Co-authored papers 1
Johns Hopkins School of Medicine
Co-authored papers 1
Finnish Institute of Occupational Health
Co-authored papers 1
University of Toronto
Co-authored papers 1
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University of California los angeles
Co-authored papers 1
University of Toronto
Co-authored papers 1
University of Jyvaskyla
Co-authored papers 1
Okinawa Institute of Science and Technology
Co-authored papers 1
Finnish National Institute for Health and Welfare
Co-authored papers 1