Author details

Full Name

Neil E Alexis

Affiliation

ORCID

Career Start Year

2000

Papers

152

H Index

Expertise

CM4AI Collaborator

PMID	Paper Title	Journal Title	Published Year
36976551	Airway and Systemic Prostaglandin E2 Association with COPD Symptoms and Macrophage Phenotype.		2023
36343688	Clinical Implications of Low Absolute Blood Eosinophil Count in the SPIROMICS COPD Cohort.	Chest	2023
36342131	Prolonged, physiologically relevant nicotine concentrations in the airways of smokers.	American Journal of Physiology - Lung Cellular and Molecular Physiology	2023
38016030	Proximal and Distal Bronchioles Contribute to the Pathogenesis of Non-Cystic Fibrosis Bronchiectasis (NCFB).		2023
37876758	A pilot randomized clinical trial of Î³-tocopherol supplementation on wood smoke-induced neutrophilic and eosinophilic airway inflammation.	J Allergy Clin Immunol Glob	2023
37217548	A blood and bronchoalveolar lavage protein signature of rapid FEV<sub>1</sub> decline in smoking-associated COPD.	Sci Rep	2023
37440094	Air Pollution and Diet: Potential Interacting Exposures in Asthma.		2023
37186612	Plasma sterols and vitamin D are correlates and predictors of ozone-induced inflammation in the lung: A pilot study.		2023
37244199	Potential mechanisms mediating PM-induced alterations of H3N2 influenza virus infection and cytokine production in human bronchial epithelial cells.		2023
36862675	Expanded characterization of in vitro polarized M0, M1, and M2 human monocyte-derived macrophages: Bioenergetic and secreted mediator profiles.		2023
37523421	Indoor Pollution and Lung Function Decline in Current and Former Smokers: SPIROMICS AIR.		2023
34748720	Combustible and Electronic Cigarette Exposures Increase ACE2 Activity and SARS-CoV-2 Spike Binding.	American Journal of Respiratory and Critical Care Medicine	2022
35968917	Development of a screening protocol to identify persons who are responsive to wood smoke particle-induced airway inflammation with pilot assessment of GSTM1 genotype and asthma status as response modifiers.	Inhal Toxicol	2022
35437233	Mucus and mucus flake composition and abundance reflect inflammatory and infection status in cystic fibrosis.	Journal of Cystic Fibrosis	2022
35731626	Biomarkers of Airway Immune Homeostasis Differ Significantly with Generation of E-Cigarettes.	American Journal of Respiratory and Critical Care Medicine	2022
35481934	Dibutyl phthalate exposure alters T-cell subsets in blood from allergen-sensitized volunteers.	Indoor Air	2022
36376879	Black carbon content in airway macrophages is associated with increased severe exacerbations and worse COPD morbidity in SPIROMICS.	Respir Res	2022
35850080	Fish oil blunts lung function decrements induced by acute exposure to ozone in young healthy adults: A randomized trial.	Environ Int	2022
35318855	Cytokine signature clusters as a tool to compare changes associated with tobacco product use in upper and lower airway samples.	American Journal of Physiology - Lung Cellular and Molecular Physiology	2022
34801592	Identification of Sputum Biomarkers Predictive of Pulmonary Exacerbations in COPD.	Chest	2022
35318050	Ambient ozone effects on respiratory outcomes among smokers modified by neighborhood poverty: An analysis of SPIROMICS AIR.	Sci Total Environ	2022
34519792	Chronic E-Cigarette Exposure Alters Human Alveolar Macrophage Morphology and Gene Expression.	Nicotine and Tobacco Research	2022
34919956	Effects of short-term increases in personal and ambient pollutant concentrations on pulmonary and cardiovascular function: A panel study analysis of the Multicenter Ozone Study in oldEr subjects (MOSES 2).	Environ Res	2022
35107034	Woodsmoke particle exposure prior to SARS-CoV-2 infection alters antiviral response gene expression in human nasal epithelial cells in a sex-dependent manner.	Am J Physiol Lung Cell Mol Physiol	2022
34462747	Woodsmoke particulates alter expression of antiviral host response genes in human nasal epithelial cells infected with SARS-CoV-2 in a sex-dependent manner.	bioRxiv	2021
33547027	Electronic Cigarettes and Their Impact on Allergic Respiratory Diseases: A Work Group Report of the AAAAI Environmental Exposures and Respiratory Health Committee.	Journal of Allergy and Clinical Immunology: In Practice	2021
34058148	Airway mucin MUC5AC and MUC5B concentrations and the initiation and progression of chronic obstructive pulmonary disease: an analysis of the SPIROMICS cohort.	Lancet Respiratory Medicine,The	2021
33932759	Associations of short-term PM exposures with nasal oxidative stress, inflammation and lung function impairment and modification by GSTT1-null genotype: A panel study of the retired adults.	Environmental Pollution	2021
34351990	Questioning the sex-specific differences in the association of smoking on the survival rate of hospitalized COVID-19 patients.	PLoS ONE	2021
33547327	Lung microbiota associations with clinical features of COPD in the SPIROMICS cohort.	NPJ Biofilms Microbiomes	2021
33315265	Relation of sputum neutrophilia to the development of chronic lung allograft dysfunction after lung transplantation.	Clinical Transplantation	2021
33400891	Respiratory Effects of Sedentary Ozone Exposure at the 70-ppb National Ambient Air Quality Standard: A Randomized Clinical Trial.	Am J Respir Crit Care Med	2021
32727225	Short course gamma tocopherol did not mitigate effects of ozone on airway inflammation in asthmatics.	Inhal Toxicol	2020
31800264	Inhibition of ATP hydrolysis restores airway surface liquid production in cystic fibrosis airway epithelia.	American Journal of Physiology - Lung Cellular and Molecular Physiology	2020
32320637	Dibutyl Phthalate Augments Allergen-induced Lung Function Decline and Alters Human Airway Immunology. A Randomized Crossover Study.	American Journal of Respiratory and Critical Care Medicine	2020
32255668	A Network of Sputum MicroRNAs Is Associated with Neutrophilic Airway Inflammation in Asthma.	Am J Respir Crit Care Med	2020
32126175	Controlled Chamber Studies Showed Protective Effect of Nonsteroidal Antiinflammatory Drugs against Ozone Exposure: The Stage Was Set for Broader Epidemiologic Investigation.	American Journal of Respiratory and Critical Care Medicine	2020
32125874	Do Ambient Ozone or Other Pollutants Modify Effects of Controlled Ozone Exposure on Pulmonary Function?	Ann Am Thorac Soc	2020
32239870	Multicenter Ozone Study in oldEr Subjects (MOSES): Part 2. Effects of Personal and Ambient Concentrations of Ozone and Other Pollutants on Cardiovascular and Pulmonary Function.	Res Rep Health Eff Inst	2020
31806722	Acute air pollution exposure alters neutrophils in never-smokers and at-risk humans.	European Respiratory Journal	2020
31113421	Tobacco exposure inhibits SPLUNC1-dependent antimicrobial activity.	Respiratory Research	2019
30684474	Systemic Markers of Inflammation in Smokers With Symptoms Despite PreservedÂ Spirometry in SPIROMICS.	Chest	2019
31013116	SPLUNC1 Loses Its Antimicrobial Activity in Acidic Cystic Fibrosis Airway Secretions.	American Journal of Respiratory and Critical Care Medicine	2019
31390877	Chronic E-Cigarette Use Increases Neutrophil Elastase and Matrix Metalloprotease Levels in the Lung.	American Journal of Respiratory and Critical Care Medicine	2019
31389736	Endotracheal tube mucus as a source of airway mucus for rheological study.	American Journal of Physiology - Lung Cellular and Molecular Physiology	2019
30790595	The glutathione-S-transferase mu-1 null genotype increases wood smoke-induced airway inflammation.	J Allergy Clin Immunol	2019
30712400	Mucus Hydration in Subjects with Stable Chronic Bronchitis: A Comparison of Spontaneous and Induced Sputum.	COPD	2018
28916185	Alveolar eosinophilia in current smokers with chronic obstructive pulmonary disease in the SPIROMICS cohort.	Journal of Allergy and Clinical Immunology	2018
28736267	Gamma tocopherol-enriched supplement reduces sputum eosinophilia and endotoxin-induced sputum neutrophilia in volunteers with asthma.	J Allergy Clin Immunol	2018
29053025	E-Cigarette Use Causes a Unique Innate Immune Response in the Lung, Involving Increased Neutrophilic Activation and Altered Mucin Secretion.	American Journal of Respiratory and Critical Care Medicine	2018