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Author Details

Richard E Straub
Lieber Institute for Brain Development
1986
132
64
PMIDPaper TitleJournal TitlePublished Year
35017298Electrophysiological measures from human iPSC-derived neurons are associated with schizophrenia clinical status and predict individual cognitive performance.Proc Natl Acad Sci U S A2022
35396580Mapping genomic loci implicates genes and synaptic biology in schizophrenia.Nature2022
33691233Genome-wide analyses of smoking behaviors in schizophrenia: Findings from the Psychiatric Genomics Consortium.J Psychiatr Res2021
30635639Schizophrenia risk variants influence multiple classes of transcripts of sorting nexin 19 (SNX19).Mol Psychiatry2020
31366918Correction: iPSC-derived homogeneous populations of developing schizophrenia cortical interneurons have compromised mitochondrial function.Mol Psychiatry2020
31019265iPSC-derived homogeneous populations of developing schizophrenia cortical interneurons have compromised mitochondrial function.Mol Psychiatry2020
30478419Identification and prioritization of gene sets associated with schizophrenia risk by co-expression network analysis in human brain.Mol Psychiatry2020
30664768Dysregulated protocadherin-pathway activity as an intrinsic defect in induced pluripotent stem cell-derived cortical interneurons from subjects with schizophrenia.Nat Neurosci2019
31374203Pleiotropic Meta-Analysis of Cognition, Education, and Schizophrenia Differentiates Roles of Early Neurodevelopmental and Adult Synaptic Pathways.Am J Hum Genet2019
30535067Polygenic risk score increases schizophrenia liability through cognition-relevant pathways.Brain2019
29415119Schizophrenia polygenic risk score predicts mnemonic hippocampal activity.Brain2018
30001766Multi-Trait Analysis of GWAS and Biological Insights Into Cognition: A Response to Hill (2018).Twin Res Hum Genet2018
29891954Variations in Dysbindin-1 are associated with cognitive response to antipsychotic drug treatment.Nat Commun2018
29808008Convergence of placenta biology and genetic risk for schizophrenia.Nat Med2018
30158661Publisher Correction: Variations in Dysbindin-1 are associated with cognitive response to antipsychotic drug treatment.Nat Commun2018
29942086Genome-wide association meta-analysis in 269,867 individuals identifies new genetic and functional links to intelligence.Nat Genet2018
30050107Developmental and genetic regulation of the human cortex transcriptome illuminate schizophrenia pathogenesis.Nat Neurosci2018
28634288qSVA framework for RNA quality correction in differential expression analysis.Proc Natl Acad Sci U S A2017
28450582Intersection of diverse neuronal genomes and neuropsychiatric disease: The Brain Somatic Mosaicism Network.Science2017
28093568GWAS meta-analysis reveals novel loci and genetic correlates for general cognitive function: a report from the COGENT consortium.Mol Psychiatry2017
29068436GWAS meta-analysis reveals novel loci and genetic correlates for general cognitive function: a report from the COGENT consortium.Mol Psychiatry2017
29186694Large-Scale Cognitive GWAS Meta-Analysis Reveals Tissue-Specific Neural Expression and Potential Nootropic Drug Targets.Cell Rep2017
26738766Genomic structure and expression of the human serotonin 2A receptor gene (HTR2A) locus: identification of novel HTR2A and antisense (HTR2A-AS1) exons.BMC Genet2016
27158905A human-specific AS3MT isoform and BORCS7 are molecular risk factors in the 10q24.32 schizophrenia-associated locus.Nat Med2016
25951819Independent evidence for an association between general cognitive ability and a genetic locus for educational attainment.Am J Med Genet B Neuropsychiatr Genet2015
23752248Paternal age, de novo mutations and schizophrenia.Mol Psychiatry2014
24695712Characteristics of the cation cotransporter NKCC1 in human brain: alternate transcripts, expression in development, and potential relationships to brain function and schizophrenia.J Neurosci2014
24718902Differential effects of common variants in SCN2A on general cognitive ability, brain physiology, and messenger RNA expression in schizophrenia cases and control individuals.JAMA Psychiatry2014
24680031Incomplete penetrance of NRXN1 deletions in families with schizophrenia.Schizophr Res2014
22115776Schizophrenia candidate gene ERBB4: covert routes of vulnerability to psychosis detected at the population level.Schizophr Bull2013
22968816Effect of schizophrenia risk-associated alleles in SREB2 (GPR85) on functional MRI phenotypes in healthy volunteers.Neuropsychopharmacology2013
23155182Variation in psychosis gene ZNF804A is associated with a refined schizotypy phenotype but not neurocognitive performance in a large young male population.Schizophr Bull2013
22689948Neuregulin 1-ErbB4-PI3K signaling in schizophrenia and phosphoinositide 3-kinase-p110δ inhibition as a potential therapeutic strategy.Proc Natl Acad Sci U S A2012
22795968Analysis of copy number variations in brain DNA from patients with schizophrenia and other psychiatric disorders.Biol Psychiatry2012
20838396GWA study data mining and independent replication identify cardiomyopathy-associated 5 (CMYA5) as a risk gene for schizophrenia.Mol Psychiatry2011
21795557Expression of GABA signaling molecules KCC2, NKCC1, and GAD1 in cortical development and schizophrenia.J Neurosci2011
21349497Evidence of sex-modulated association of ZNF804A with schizophrenia.Biol Psychiatry2011
20087814Progranulin (GRN) in two siblings of a Latino family and in other patients with schizophrenia.Neurocase2010
20819988Genetic variation in CACNA1C affects brain circuitries related to mental illness.Arch Gen Psychiatry2010
20921115Biological validation of increased schizophrenia risk with NRG1, ERBB4, and AKT1 epistasis via functional neuroimaging in healthy controls.Arch Gen Psychiatry2010
20427658Genetic variation in FGF20 modulates hippocampal biology.J Neurosci2010
20357758Genetic modulation of GABA levels in the anterior cingulate cortex by GAD1 and COMT.Neuropsychopharmacology2010
19626024A 5' promoter region SNP in NRG1 is associated with schizophrenia risk and type III isoform expression.Mol Psychiatry2009
17707347Genetic variation in catechol-O-methyltransferase: effects on working memory in schizophrenic patients, their siblings, and healthy controls.Biol Psychiatry2008
18989458Functional polymorphisms in PRODH are associated with risk and protection for schizophrenia and fronto-striatal structure and function.PLoS Genet2008
18497887Genetic variation in AKT1 is linked to dopamine-associated prefrontal cortical structure and function in humans.J Clin Invest2008
18255048Novel linkage to chromosome 20p using latent classes of psychotic illness in 270 Irish high-density families.Biol Psychiatry2008
18413613The evolutionarily conserved G protein-coupled receptor SREB2/GPR85 influences brain size, behavior, and vulnerability to schizophrenia.Proc Natl Acad Sci U S A2008
18424448Variants in the estrogen receptor alpha gene and its mRNA contribute to risk for schizophrenia.Hum Mol Genet2008
17961984Reduced DTNBP1 (dysbindin-1) mRNA in the hippocampal formation of schizophrenia patients.Schizophr Res2008
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Collaborators

Co-authored papers 75
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Co-authored papers 28
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University of North Carolina at Chapel Hill
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Johns Hopkins School of Medicine
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University of Oslo
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University of Oslo, Oslo University Hospital
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University of Bergen
Co-authored papers 7
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University of Oslo
Co-authored papers 7
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Co-authored papers 7