Author details

Full Name

Yuan-Tsong Chen

Affiliation

ORCID

Career Start Year

1978

Papers

195

H Index

Expertise

CM4AI Collaborator

PMID	Paper Title	Journal Title	Published Year
37034649	Multi-ancestry genome-wide study in >2.5 million individuals reveals heterogeneity in mechanistic pathways of type 2 diabetes and complications.	medRxiv	2023
37824212	Cell-based screen identifies porphyrins as FGFR3 activity inhibitors with therapeutic potential for achondroplasia and cancer.		2023
35146182	Spontaneous resolution of recurrent Descemet's membrane detachment after trabeculectomy: A case report.	American Journal of Ophthalmology Case Reports	2022
36303164	Enrichment of Prevotella intermedia in human colorectal cancer and its additive effects with Fusobacterium nucleatum on the malignant transformation of colorectal adenomas.	Journal of Biomedical Science	2022
35551307	Multi-ancestry genetic study of type 2 diabetes highlights the power of diverse populations for discovery and translation.	Nat Genet	2022
33106546	Association of an IGHV3-66 gene variant with Kawasaki disease.	J Hum Genet	2021
31669413	Palmitoyl Acyltransferase Activity of ZDHHC13 Regulates Skin Barrier Development Partly by Controlling PADi3 and TGM1 Protein Stability.	J Invest Dermatol	2020
30674924	Genome-wide transcriptome analysis to further understand neutrophil activation and lncRNA transcript profiles in Kawasaki disease.	Scientific Reports	2019
31877813	Both IgM and IgG Antibodies Against Polyethylene Glycol Can Alter the Biological Activity of Methoxy Polyethylene Glycol-Epoetin Beta in Mice.	Pharmaceutics	2019
29771320	Immunoglobulin profiling identifies unique signatures in patients with Kawasaki disease during intravenous immunoglobulin treatment.	Human Molecular Genetics	2018
28952330	Genome-wide association study identifies novel susceptibility loci for migraine in Han Chinese resided in Taiwan.	Cephalalgia	2018
30487518	Interethnic analyses of blood pressure loci in populations of East Asian and European descent.	Nat Commun	2018
29392710	Clinical Pharmacogenetics Implementation Consortium Guideline for HLA Genotype and Use of Carbamazepine and Oxcarbazepine: 2017 Update.	Clin Pharmacol Ther	2018
29336782	Loss of GPNMB Causes Autosomal-Recessive Amyloidosis Cutis Dyschromica in Humans.	American Journal of Human Genetics	2018
28145000	Filamin B Loss-of-Function Mutation in Dimerization Domain Causes Autosomal-Recessive Spondylocarpotarsal Synostosis Syndrome with Rib Anomalies.	Human Mutation	2017
28900105	A genome-wide association study identifies a novel susceptibility locus for the immunogenicity of polyethylene glycol.	Nature Communications	2017
28377241	Genetic epidemiological study doesn't support GLA IVS4+919G>A variant is a significant mutation in Fabry disease.	Molecular Genetics and Metabolism	2017
28334899	Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.	Hum Mol Genet	2017
28526873	Role of S-Palmitoylation by ZDHHC13 in Mitochondrial function and Metabolism in Liver.	Sci Rep	2017
29123153	A genome-wide association study links small-vessel ischemic stroke to autophagy.	Scientific Reports	2017
29121990	Identification of functional single nucleotide polymorphisms in the branchpoint site.	Human Genomics	2017
28017833	Protein Palmitoylation by ZDHHC13 Protects Skin against Microbial-Driven Dermatitis.		2017
28017375	Genome-wide Trans-ethnic Meta-analysis Identifies Seven Genetic Loci Influencing Erythrocyte Traits and a Role for RBPMS in Erythropoiesis.	Am J Hum Genet	2017
28230213	Knock-in human FGFR3 achondroplasia mutation as a mouse model for human skeletal dysplasia.	Scientific Reports	2017
27995809	Correlations between the enantio- and regio-selective metabolisms of warfarin.	Pharmacogenomics	2017
27503578	Population differences in S-warfarin pharmacokinetics among African Americans, Asians and whites: their influence on pharmacogenetic dosing algorithms.	Pharmacogenomics J	2017
28112575	Pharmacogenetic dosing of warfarin in the Han-Chinese population: a randomized trial.	Pharmacogenomics	2017
27726379	Measurement of Pre-Existing IgG and IgM Antibodies against Polyethylene Glycol in Healthy Individuals.	Analytical Chemistry	2016
27025970	Identification of PTCSC3 as a Novel Locus for Large-Vessel Ischemic Stroke: A Genome-Wide Association Study.	Journal of the American Heart Association	2016
26935888	Novel susceptibility gene for nonfamilial hypokalemic periodic paralysis.	Neurology	2016
27391550	Homozygosity Mapping and Whole-Genome Sequencing Links a Missense Mutation in POMGNT1 to Autosomal Recessive Retinitis Pigmentosa.	Investigative Ophthalmology and Visual Science	2016
26976339	Pharmacogenomics for personalized pain medicine.		2016
27329586	Over-expression of AURKA, SKA3 and DSN1 contributes to colorectal adenoma to carcinoma progression.	Oncotarget	2016
27276051	Antimicrobial Properties of an Immunomodulator - 15 kDa Human Granulysin.	PLoS ONE	2016
26785701	Genome-wide association studies in East Asians identify new loci for waist-hip ratio and waist circumference.	Sci Rep	2016
27042285	Genome-wide analysis of copy number variations identifies PARK2 as a candidate gene for autism spectrum disorder.	Molecular Autism	2016
26951484	Use of the Biopharmaceutics Drug Disposition Classification System (BDDCS) to Help Predict the Occurrence of Idiosyncratic Cutaneous Adverse Drug Reactions Associated with Antiepileptic Drug Usage.	AAPS Journal	2016
27029637	An integrated analysis tool for analyzing hybridization intensities and genotypes using new-generation population-optimized human arrays.	BMC Genomics	2016
27798100	Population structure of Han Chinese in the modern Taiwanese population based on 10,000 participants in the Taiwan Biobank project.	Human Molecular Genetics	2016
27503288	Identification of susceptibility gene associated with female primary SjÃ¶gren's syndrome in Han Chinese by genome-wide association study.	Human Genetics	2016
26151496	Genetic determinants of antithyroid drug-induced agranulocytosis by human leukocyte antigen genotyping and genome-wide association study.	Nature Communications	2015
25458913	Immunologic basis for allopurinol-induced severe cutaneous adverse reactions: HLA-B*58:01-restricted activation of drug-specific T cells and molecular interaction.	Journal of Allergy and Clinical Immunology	2015
25410879	Association of circadian genes with diurnal blood pressure changes and non-dipper essential hypertension: a genetic association with young-onset hypertension.	Hypertension Research	2015
25910225	Loss of PTPRM associates with the pathogenic development of colorectal adenoma-carcinoma sequence.	Scientific Reports	2015
25605650	CXCL10/IP-10 is a biomarker and mediator for Kawasaki disease.	Circulation Research	2015
26399967	Use of HLA-B*58:01 genotyping to prevent allopurinol induced severe cutaneous adverse reactions in Taiwan: national prospective cohort study.	BMJ, The	2015
26390057	Trans-ancestry genome-wide association study identifies 12 genetic loci influencing blood pressure and implicates a role for DNA methylation.	Nat Genet	2015
26121212	Cyclic Alopecia and Abnormal Epidermal Cornification in Zdhhc13-Deficient Mice Reveal the Importance of Palmitoylation in Hair and Skin Differentiation.	J Invest Dermatol	2015
24509480	Genome-wide trans-ancestry meta-analysis provides insight into the genetic architecture of type 2 diabetes susceptibility.	Nat Genet	2014
24357089	Genetic polymorphisms of metabolic enzymes and the pharmacokinetics of indapamide in Taiwanese subjects.	AAPS Journal	2014