Author details

Full Name

Srinivasan Ramachandran

Affiliation

ORCID

Career Start Year

2002

Papers

H Index

Expertise

CM4AI Collaborator

PMID	Paper Title	Journal Title	Published Year
37924159	Limitations of the human iPSC-derived neuron model for early-onset Alzheimer's disease.	Mol Brain	2023
37849634	Endotype Characterization Reveals Mechanistic Differences Across Brain Regions in Sporadic Alzheimer's Disease.	J Alzheimers Dis Rep	2023
37983749	MetGENE: gene-centric metabolomics information retrieval tool.	Gigascience	2022
36224601	Transcriptomic profiling of sporadic Alzheimer's disease patients.	Mol Brain	2022
35672450	ARID1B, a molecular suppressor of erythropoiesis, is essential for the prevention of Monge's disease.	Exp Mol Med	2022
34595164	Heme Oxygenase-1 at the Nexus of Endothelial Cell Fate Decision Under Oxidative Stress.	Front Cell Dev Biol	2021
32407064	Direct DNA Methylation Profiling with an Electric Biosensor.	ACS Nano	2020
31013385	Generating Cyan Fluorescence with De Novo Tripeptides: An In Vitro Mutation Study on the Role of Single Amino Acid Residues and Their Sequence.	ChemBioChem	2019
29401382	Micromachined Chip Scale Thermal Sensor for Thermal Imaging.	ACS Nano	2018
26453217	Computational Methods for Structural and Functional Studies of Alzheimer's Amyloid Ion Channels.	Methods Mol Biol	2016
27335341	Small molecule NPT-440-1 inhibits ionic flux through AÎ²<sub>1-42</sub> pores: Implications for Alzheimer's disease therapeutics.	Nanomedicine	2016
26953146	Oligomerization of the microtubule-associated protein tau is mediated by its N-terminal sequences: implications for normal and pathological tau action.	Journal of Neurochemistry	2016
26575330	Ion Channel Formation by Tau Protein: Implications for Alzheimer's Disease and Tauopathies.	Biochemistry	2015
24922585	Activity and architecture of pyroglutamate-modified amyloid-Î² (AÎ²pE3-42) pores.	J Phys Chem B	2014
24075148	Influence of time and length size feature selections for human activity sequences recognition.		2014
24950761	Role of the fast kinetics of pyroglutamate-modified amyloid-Î² oligomers in membrane binding and membrane permeability.	Biochemistry	2014
24979064	Measuring localized redox enzyme electron transfer in a live cell with conducting atomic force microscopy.	Analytical Chemistry	2014
24566672	Disordered amyloidogenic peptides may insert into the membrane and assemble into common cyclic structural motifs.	Chem Soc Rev	2014
24651823	Structure and permeability of ion-channels by integrated AFM and waveguide TIRF microscopy.	Scientific Reports	2014
23450150	Alzheimer's disease: which type of amyloid-preventing drug agents to employ?	Phys Chem Chem Phys	2013
22779439	Genetic improvement of plants for enhanced bio-ethanol production.	Recent patents on DNA & gene sequences	2013
24000923	Familial Alzheimer's disease Osaka mutant (Î¿E22) Î²-barrels suggest an explanation for the different AÎ²1-40/42 preferred conformational states observed by experiment.	J Phys Chem B	2013
23823601	High performance, LED powered, waveguide based total internal reflection microscopy.	Scientific Reports	2013
23316126	Mechanisms for the Insertion of Toxic, Fibril-like Î²-Amyloid Oligomers into the Membrane.	J Chem Theory Comput	2013
22081976	Antimicrobial properties of amyloid peptides.	Mol Pharm	2012
22423218	All-d-Enantiomer of Î²-Amyloid Peptide Forms Ion Channels in Lipid Bilayers.	J Chem Theory Comput	2012
22413858	Effects of point substitutions on the structure of toxic Alzheimer's Î²-amyloid channels: atomic force microscopy and molecular dynamics simulations.	Biochemistry	2012
22864749	The effects of ginsenoside Rb1 on JNK in oxidative injury in cardiomyocytes.	Archives of Pharmacal Research	2012
23063548	Magnetic targeting of nanoparticles across the intact blood-brain barrier.	Journal of Controlled Release	2012
21930207	Mutant SOD1 forms ion channel: implications for ALS pathophysiology.	Neurobiology of Disease	2012
22217000	Atomic force microscopy and MD simulations reveal pore-like structures of all-D-enantiomer of Alzheimer's Î²-amyloid peptide: relevance to the ion channel mechanism of AD pathology.	J Phys Chem B	2012
21875130	DNA zipper-based tweezers.	Langmuir	2012
21618589	Baicalein protects against doxorubicin-induced cardiotoxicity by attenuation of mitochondrial oxidant injury and JNK activation.	Journal of Cellular Biochemistry	2011
21463591	Antimicrobial protegrin-1 forms amyloid-like fibrils with rapid kinetics suggesting a functional link.	Biophys J	2011
21766465	Potential role of atomic force microscopy in systems biology.	Wiley Interdisciplinary Reviews: Systems Biology and Medicine	2011
21918653	Polymorphism of amyloid Î² peptide in different environments: implications for membrane insertion and pore formation.	Soft Matter	2011
20503473	Grape seed proanthocyanidins ameliorate Doxorubicin-induced cardiotoxicity.		2010
21299045	Scope of atomic force microscopy in the advancement of nanomedicine.	Indian Journal of Experimental Biology (discontinued)	2010
20970427	Î²-Barrel topology of Alzheimer's Î²-amyloid ion channels.	J Mol Biol	2010
20957528	Multidimensional atomic force microscopy: a versatile novel technology for nanopharmacology research.	AAPS Journal	2010
20608696	Structural convergence among diverse, toxic beta-sheet ion channels.	J Phys Chem B	2010
20382860	Therapeutic hypothermia cardioprotection via Akt- and nitric oxide-mediated attenuation of mitochondrial oxidants.	American Journal of Physiology - Heart and Circulatory Physiology	2010
20308552	Truncated beta-amyloid peptide channels provide an alternative mechanism for Alzheimer's Disease and Down syndrome.	Proc Natl Acad Sci U S A	2010
19948133	Misfolded amyloid ion channels present mobile beta-sheet subunits in contrast to conventional ion channels.	Biophys J	2009
19824733	K3 fragment of amyloidogenic beta(2)-microglobulin forms ion channels: implication for dialysis related amyloidosis.	J Am Chem Soc	2009
17241061	Atomic force microscopy imaging and electrical recording of lipid bilayers supported over microfabricated silicon chip nanopores: lab-on-a-chip system for lipid membranes and ion channels.	Langmuir	2007
17684558	A novel role for connexin hemichannel in oxidative stress and smoking-induced cell injury.	PLoS One	2007
16952256	Cisplatin nanoliposomes for cancer therapy: AFM and fluorescence imaging of cisplatin encapsulation, stability, cellular uptake, and toxicity.	Langmuir	2006
16769719	Nanomechanics of hemichannel conformations: connexin flexibility underlying channel opening and closing.	Journal of Biological Chemistry	2006
17066169	Piezoresistive cantilever based nanoflow and viscosity sensor for microchannels.	Lab on a Chip	2006