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Author Details

Hui Shen
Van Andel Institute
2010
68
45
Trey Ideker (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
36928921A Phase II Trial of Guadecitabine plus Atezolizumab in Metastatic Urothelial Carcinoma Progressing after Initial Immune Checkpoint Inhibitor Therapy.Clin Cancer Res2023
36585450Multiomics in primary and metastatic breast tumors from the AURORA US network finds microenvironment and epigenetic drivers of metastasis.Nat Cancer2023
37461447A Novel Humanized Immune Stroma PDX Cancer Model for Therapeutic Studies.bioRxiv2023
36948185Epigenetic dosage identifies two major and functionally distinct β cell subtypes.Cell Metab2023
37380777Cancer aneuploidies are shaped primarily by effects on tumour fitness.Nature2023
36928921A Phase II Trial of Guadecitabine plus Atezolizumab in Metastatic Urothelial Carcinoma Progressing after Initial Immune Checkpoint Inhibitor Therapy.Clin Cancer Res2023
36459996Subclonal mutations in epigenetic regulators bring fitness in times of stress.Cancer Cell2023
37461447A Novel Humanized Immune Stroma PDX Cancer Model for Therapeutic Studies.bioRxiv2023
36948185Epigenetic dosage identifies two major and functionally distinct β cell subtypes.Cell Metab2023
37380777Cancer aneuploidies are shaped primarily by effects on tumour fitness.Nature2023
36585450Multiomics in primary and metastatic breast tumors from the AURORA US network finds microenvironment and epigenetic drivers of metastasis.Nat Cancer2023
36459996Subclonal mutations in epigenetic regulators bring fitness in times of stress.Cancer Cell2023
36347867Cell division drives DNA methylation loss in late-replicating domains in primary human cells.Nat Commun2022
35654826Chromosome-specific retention of cancer-associated DNA hypermethylation following pharmacological inhibition of DNMT1.Commun Biol2022
36347867Cell division drives DNA methylation loss in late-replicating domains in primary human cells.Nat Commun2022
35873672DNA methylation dynamics and dysregulation delineated by high-throughput profiling in the mouse.Cell Genom2022
36066972Transcriptome and DNA methylome analyses reveal underlying mechanisms for the racial disparity in uterine fibroids.JCI Insight2022
36402747PRDM15 interacts with DNA-PK-Ku complex to promote radioresistance in rectal cancer by facilitating DNA damage repair.Cell Death Dis2022
35654826Chromosome-specific retention of cancer-associated DNA hypermethylation following pharmacological inhibition of DNMT1.Commun Biol2022
36402747PRDM15 interacts with DNA-PK-Ku complex to promote radioresistance in rectal cancer by facilitating DNA damage repair.Cell Death Dis2022
35873672DNA methylation dynamics and dysregulation delineated by high-throughput profiling in the mouse.Cell Genom2022
36066972Transcriptome and DNA methylome analyses reveal underlying mechanisms for the racial disparity in uterine fibroids.JCI Insight2022
32339229The Exceptional Responders Initiative: Feasibility of a National Cancer Institute Pilot Study.J Natl Cancer Inst2021
32339229The Exceptional Responders Initiative: Feasibility of a National Cancer Institute Pilot Study.J Natl Cancer Inst2021
34147133Evaluation of whole-genome DNA methylation sequencing library preparation protocols.Epigenetics Chromatin2021
33217343Molecular Features of Cancers Exhibiting Exceptional Responses to Treatment.Cancer Cell2021
34147133Evaluation of whole-genome DNA methylation sequencing library preparation protocols.Epigenetics Chromatin2021
33217343Molecular Features of Cancers Exhibiting Exceptional Responses to Treatment.Cancer Cell2021
32641237Menopausal hormone therapy prior to the diagnosis of ovarian cancer is associated with improved survival.Gynecol Oncol2020
32641237Menopausal hormone therapy prior to the diagnosis of ovarian cancer is associated with improved survival.Gynecol Oncol2020
33296650Epigenomic Reprogramming toward Mesenchymal-Epithelial Transition in Ovarian-Cancer-Associated Mesenchymal Stem Cells Drives Metastasis.Cell Rep2020
35117726The efficacy of afatinib in patients with <i>HER2</i> mutant non-small cell lung cancer: a meta-analysis.Transl Cancer Res2020
35117726The efficacy of afatinib in patients with <i>HER2</i> mutant non-small cell lung cancer: a meta-analysis.Transl Cancer Res2020
33296650Epigenomic Reprogramming toward Mesenchymal-Epithelial Transition in Ovarian-Cancer-Associated Mesenchymal Stem Cells Drives Metastasis.Cell Rep2020
31037156Non-invasive diagnosis of early-stage lung cancer using high-throughput targeted DNA methylation sequencing of circulating tumor DNA (ctDNA).Theranostics2019
31851934Integrated Epigenome, Exome, and Transcriptome Analyses Reveal Molecular Subtypes and Homeotic Transformation in Uterine Fibroids.Cell Rep2019
31037156Non-invasive diagnosis of early-stage lung cancer using high-throughput targeted DNA methylation sequencing of circulating tumor DNA (ctDNA).Theranostics2019
31433971The Immune Landscape of Cancer.Immunity2019
31391455ARID1A and PI3-kinase pathway mutations in the endometrium drive epithelial transdifferentiation and collective invasion.Nat Commun2019
31851934Integrated Epigenome, Exome, and Transcriptome Analyses Reveal Molecular Subtypes and Homeotic Transformation in Uterine Fibroids.Cell Rep2019
31433971The Immune Landscape of Cancer.Immunity2019
31391455ARID1A and PI3-kinase pathway mutations in the endometrium drive epithelial transdifferentiation and collective invasion.Nat Commun2019
29622464A Comprehensive Pan-Cancer Molecular Study of Gynecologic and Breast Cancers.Cancer Cell2018
29925010The Cancer Genome Atlas Comprehensive Molecular Characterization of Renal Cell Carcinoma.Cell Rep2018
30085201SeSAMe: reducing artifactual detection of DNA methylation by Infinium BeadChips in genomic deletions.Nucleic Acids Res2018
29898407Integrated Molecular Characterization of Testicular Germ Cell Tumors.Cell Rep2018
29535383A LATS biosensor screen identifies VEGFR as a regulator of the Hippo pathway in angiogenesis.Nat Commun2018
29625050Oncogenic Signaling Pathways in The Cancer Genome Atlas.Cell2018
29622464A Comprehensive Pan-Cancer Molecular Study of Gynecologic and Breast Cancers.Cancer Cell2018
29617669The Cancer Genome Atlas Comprehensive Molecular Characterization of Renal Cell Carcinoma.Cell Rep2018
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Collaborators

Van Andel Institute
Co-authored papers 43
Dana-Farber Cancer Institute
Co-authored papers 17
Present address: Dxige Research Inc.
Co-authored papers 12
Knight Cancer Institute, Oregon Health and Sciences University
Co-authored papers 11
The University of Texas MD Anderson Cancer Center
Co-authored papers 11
Co-authored papers 11
University of Pennsylvania
Co-authored papers 10
Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill
Co-authored papers 10
Co-authored papers 10
Broad Institute
Co-authored papers 8
Baylor College of Medicine
Co-authored papers 8
The University of Texas MD Anderson Cancer Center
Co-authored papers 8
Center for Precision Health, The University of Texas Health Science Center at Houston
Co-authored papers 8
Co-authored papers 8
University of California San Francisco
Co-authored papers 7
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins University
Co-authored papers 7
Co-authored papers 7
Co-authored papers 7
Nationwide Children's Hospital
Co-authored papers 6
Co-authored papers 6
The University of Texas MD Anderson Cancer Center
Co-authored papers 6
Memorial Sloan Kettering Cancer Center
Co-authored papers 6
Henry Ford Hospital
Co-authored papers 6
Nationwide Children's Hospital
Co-authored papers 6
McDonnell Genome Institute, Washington University School of Medicine
Co-authored papers 6
Perlmutter Cancer Center
Co-authored papers 6
Broad Institute of the Massachusetts Institute of Technology and Harvard
Co-authored papers 6
Buck Institute for Research on Aging
Co-authored papers 6
Washington University
Co-authored papers 5
Co-authored papers 5