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Author Details

Deborah A Lewinsohn
Oregon Health and Science University
1996
67
33
PMIDPaper TitleJournal TitlePublished Year
37275871Mycobacterial-specific secretion of cytokines and chemokines in healthcare workers with apparent resistance to infection with <i>Mycobacterium tuberculosis</i>.Front Immunol2023
38003817Production of Proinflammatory Cytokines by CD4+ and CD8+ T Cells in Response to Mycobacterial Antigens among Children and Adults with Tuberculosis.Pathogens2023
37693561Modulation of riboflavin biosynthesis and utilization in mycobacteria.bioRxiv2023
36581641Deaza-modification of MR1 ligands modulates recognition by MR1-restricted T cells.Sci Rep2022
35493495The Missing Link in Correlates of Protective Tuberculosis Immunity: Recognizing the Infected Cell.Front Immunol2022
33360378T cell receptor diversity, specificity and promiscuity of functionally heterogeneous human MR1-restricted T cells.Mol Immunol2021
33828558Functional and Activation Profiles of Mucosal-Associated Invariant T Cells in Patients With Tuberculosis and HIV in a High Endemic Setting.Front Immunol2021
34740474Donor Unrestricted T Cells: Linking innate and adaptive immunity.Vaccine2021
33042140Postnatal Expansion, Maturation, and Functionality of MR1T Cells in Humans.Front Immunol2020
31763996Clonal enrichments of Vδ2- γδ T cells in Mycobacterium tuberculosis-infected human lungs.J Clin Invest2020
30335466Moving toward Tuberculosis Elimination. Critical Issues for Research in Diagnostics and Therapeutics for Tuberculosis Infection.Am J Respir Crit Care Med2019
31731979New Concepts in Tuberculosis Host Defense.Clin Chest Med2019
31221543The evolving research agenda for paediatric tuberculosis infection.Lancet Infect Dis2019
30923183Recognition of CD8<sup>+</sup> T-cell epitopes to identify adults with pulmonary tuberculosis.Eur Respir J2019
29661928Identification and Evaluation of Novel Protective Antigens for the Development of a Candidate Tuberculosis Subunit Vaccine.Infect Immun2018
30006464MR1 displays the microbial metabolome driving selective MR1-restricted T cell receptor usage.Sci Immunol2018
30514508Characterization of specific CD4 and CD8 T-cell responses in QuantiFERON TB Gold-Plus TB1 and TB2 tubes.Tuberculosis (Edinb)2018
27759023MR1-restricted mucosal-associated invariant T (MAIT) cells respond to mycobacterial vaccination and infection in nonhuman primates.Mucosal Immunol2017
29176828T cell recognition of Mycobacterium tuberculosis peptides presented by HLA-E derived from infected human cells.PLoS One2017
29051764Polyfunctional CD4<sup>+</sup> T Cells As Targets for Tuberculosis Vaccination.Front Immunol2017
28676677HLA-E Presents Glycopeptides from the Mycobacterium tuberculosis Protein MPT32 to Human CD8<sup>+</sup> T cells.Sci Rep2017
28775896Comprehensive definition of human immunodominant CD8 antigens in tuberculosis.NPJ Vaccines2017
27932390Official American Thoracic Society/Infectious Diseases Society of America/Centers for Disease Control and Prevention Clinical Practice Guidelines: Diagnosis of Tuberculosis in Adults and Children.Clin Infect Dis2017
28052967Official American Thoracic Society/Infectious Diseases Society of America/Centers for Disease Control and Prevention Clinical Practice Guidelines: Diagnosis of Tuberculosis in Adults and Children.Clin Infect Dis2017
27194790Direct TLR-2 Costimulation Unmasks the Proinflammatory Potential of Neonatal CD4+ T Cells.J Immunol2016
27805026Adenovirally-Induced Polyfunctional T Cells Do Not Necessarily Recognize the Infected Target: Lessons from a Phase I Trial of the AERAS-402 Vaccine.Sci Rep2016
25752900High expression of CD26 accurately identifies human bacteria-reactive MR1-restricted MAIT cells.Immunology2015
24852051Antigens for CD4 and CD8 T cells in tuberculosis.Cold Spring Harb Perspect Med2014
25049333MR1-restricted MAIT cells display ligand discrimination and pathogen selectivity through distinct T cell receptor usage.J Exp Med2014
24818967Childhood tuberculosis in northern Viet Nam: a review of 103 cases.PLoS One2014
22692454Human thymic MR1-restricted MAIT cells are innate pathogen-reactive effectors that adapt following thymic egress.Mucosal Immunol2013
24324704Mycobacterium tuberculosis specific CD8(+) T cells rapidly decline with antituberculosis treatment.PLoS One2013
24244525TAP mediates import of Mycobacterium tuberculosis-derived peptides into phagosomes and facilitates loading onto HLA-I.PLoS One2013
23805289Human Mycobacterium tuberculosis CD8 T Cell Antigens/Epitopes Identified by a Proteomic Peptide Library.PLoS One2013
21963623Safety and efficacy of CMX001 as salvage therapy for severe adenovirus infections in immunocompromised patients.Biol Blood Marrow Transplant2012
22476719Evaluation of tuberculosis diagnostics in children: 2. Methodological issues for conducting and reporting research evaluations of tuberculosis diagnostics for intrathoracic tuberculosis in children. Consensus from an expert panel.J Infect Dis2012
22071329CD8+ T cells provide an immunologic signature of tuberculosis in young children.Am J Respir Crit Care Med2012
21349084Views of immunology: effector T cells.Immunol Rev2011
19952926Interferon-gamma release assays: new diagnostic tests for Mycobacterium tuberculosis infection, and their use in children.Curr Opin Pediatr2010
20802151Secreted immunodominant Mycobacterium tuberculosis antigens are processed by the cytosolic pathway.J Immunol2010
20613858Human mucosal associated invariant T cells detect bacterially infected cells.PLoS Biol2010
19283913New diagnostic methods for tuberculosis.Curr Opin Infect Dis2009
19593251Embracing interferon-gamma release assays for diagnosis of latent tuberculosis infection.Pediatr Infect Dis J2009
19360129The Mycobacterium tuberculosis phagosome is a HLA-I processing competent organelle.PLoS Pathog2009
18209663Immunologic susceptibility of young children to Mycobacterium tuberculosis.Pediatr Res2008
18923705Whole blood interferon-gamma responses to mycobacterium tuberculosis antigens in young household contacts of persons with tuberculosis in Uganda.PLoS One2008
18550653Interferon-gamma release assays for diagnosing mycobacterium tuberculosis infection in renal dialysis patients.Clin J Am Soc Nephrol2008
18282101Human innate Mycobacterium tuberculosis-reactive alphabetaTCR+ thymocytes.PLoS Pathog2008
17892322Immunodominant tuberculosis CD8 antigens preferentially restricted by HLA-B.PLoS Pathog2007
17895997Human neonatal dendritic cells are competent in MHC class I antigen processing and presentation.PLoS One2007
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Collaborators

David M Lewinsohn
Oregon Health and Science University
Co-authored papers 50
Gwendolyn M Swarbrick
Oregon Health and Science University
Co-authored papers 19
Megan D Null
Oregon Health and Science University
Co-authored papers 14
Meghan E Cansler
Oregon Health and Science University
Co-authored papers 13
Melissa Nyendak
Oregon Health and Science University
Co-authored papers 8
Harriet Mayanja-Kizza
Case Western Reserve University
Co-authored papers 7
William Henry Boom
Case Western Reserve University and University Hospitals Cleveland Medical Center
Co-authored papers 6
Byung Park
Oregon Health & Science University
Co-authored papers 5
Joy Baseke
Busitema University
Co-authored papers 4
William H Hildebrand
University of Oklahoma Health Sciences Center
Co-authored papers 4
Sarah Zalwango
School of Public Health, Makerere University
Co-authored papers 3
LaShaunda L Malone
Tuberculosis Research Unit, Case Western Reserve University School of Medicine
Co-authored papers 3
David R Sherman
University of Washington
Co-authored papers 2
Ted H Hansen
Co-authored papers 2
Katelynne Gardner Toren
University of Washington
Co-authored papers 2
Tomi Mori
St. Jude Children's Research Hospital
Co-authored papers 2
Shannon K McWeeney
Oregon Health & Science University, University of California Berkeley
Co-authored papers 2
Keith Chervenak
Case Western Reserve University
Co-authored papers 2
Marisa Frieder
Portland VA Medical Center, 3710 U.S. Veterans Hospital Road
Co-authored papers 2
Alessandro Sette
Center for Infectious Disease and Vaccine Research, La Jolla Institute for Immunology
Co-authored papers 2
Adithya Cattamanchi
University of California Irvine
Co-authored papers 1
Guanming Wu
Oregon Health and Science University
Co-authored papers 1
Louis J Picker
Vaccine and Gene Therapy Institute, Oregon Health & Science University
Co-authored papers 1
Michael Emerman
Fred Hutchinson Cancer Center
Co-authored papers 1
Pradyot Dash
St. Jude Children's Research Hospital
Co-authored papers 1
Maria Laura Gennaro
Public Health Research Institute, Rutgers New Jersey Medical School
Co-authored papers 1
Susan Swindells
University of Nebraska Medical Center
Co-authored papers 1
John Sidney
Co-authored papers 1
Salmaan Keshavjee
Harvard Medical School
Co-authored papers 1
Kristine M Guinn
Harvard T. H. Chan School of Public Health
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Release 1.2