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Author Details

Bruno Lemaitre
Global Health Institute, Ecole Polytechnique Federale de Lausanne (EPFL)
1991
178
73
PMIDPaper TitleJournal TitlePublished Year
36847474Antimicrobial peptides do not directly contribute to aging in Drosophila, but improve lifespan by preventing dysbiosis.Dis Model Mech2023
37493353Protein target highlights in CASP15: Analysis of models by structure providers.Proteins2023
37251515The New Microbiology: an international lecture course on the island of Spetses.Microlife2023
36976648CERT1 mutations perturb human development by disrupting sphingolipid homeostasis.J Clin Invest2023
37471548Ecology-relevant bacteria drive the evolution of host antimicrobial peptides in <i>Drosophila</i>.Science2023
34791204Cecropins contribute to Drosophila host defense against a subset of fungal and Gram-negative bacterial infection.Genetics2022
35730150<i>Drosophila</i> immunity: the <i>Drosocin</i> gene encodes two host defence peptides with pathogen-specific roles.Proc Biol Sci2022
35858432Disproportionate investment in Spiralin B production limits in-host growth and favors the vertical transmission of <i>Spiroplasma</i> insect endosymbionts.Proc Natl Acad Sci U S A2022
35714143Repeated truncation of a modular antimicrobial peptide gene for neural context.PLoS Genet2022
36260997Compartmentalized PGRP expression along the dipteran Bactrocera dorsalis gut forms a zone of protection for symbiotic bacteria.Cell Rep2022
33372708Steroid-dependent switch of OvoL/Shavenbaby controls self-renewal versus differentiation of intestinal stem cells.EMBO J2021
37223258The iron transporter Transferrin 1 mediates homeostasis of the endosymbiotic relationship between <i>Drosophila melanogaster</i> and <i>Spiroplasma poulsonii</i>.Microlife2021
33591248Rapid molecular evolution of <i>Spiroplasma</i> symbionts of <i>Drosophila</i>.Microb Genom2021
33914801Dual proteomics of Drosophila melanogaster hemolymph infected with the heritable endosymbiont Spiroplasma poulsonii.PLoS One2021
34888500The wall-less bacterium <i>Spiroplasma poulsonii</i> builds a polymeric cytoskeleton composed of interacting MreB isoforms.iScience2021
34432851The Drosophila Baramicin polypeptide gene protects against fungal infection.PLoS Pathog2021
34253067<i>Drosophila</i> Antimicrobial Peptides and Lysozymes Regulate Gut Microbiota Composition and Abundance.mBio2021
34370384A secreted factor NimrodB4 promotes the elimination of apoptotic corpses by phagocytes in Drosophila.EMBO Rep2021
33434525Autophagy as a Gatekeeper of Intestinal Homeostasis.Dev Cell2021
32444468Transformation of the <i>Drosophila</i> Sex-Manipulative Endosymbiont Spiroplasma poulsonii and Persisting Hurdles for Functional Genetic Studies.Appl Environ Microbiol2020
31835066New insights on Drosophila antimicrobial peptide function in host defense and beyond.Curr Opin Immunol2020
32075729Renal Purge of Hemolymphatic Lipids Prevents the Accumulation of ROS-Induced Inflammatory Oxidized Lipids and Protects Drosophila from Tissue Damage.Immunity2020
32009293The adipokine NimrodB5 regulates peripheral hematopoiesis in Drosophila.FEBS J2020
31912942Blind killing of both male and female Drosophila embryos by a natural variant of the endosymbiotic bacterium Spiroplasma poulsonii.Cell Microbiol2020
33177190Growing Ungrowable Bacteria: Overview and Perspectives on Insect Symbiont Culturability.Microbiol Mol Biol Rev2020
32598400Comparative RNA-Seq analyses of Drosophila plasmatocytes reveal gene specific signatures in response to clean injury and septic injury.PLoS One2020
32188787Iron sequestration by transferrin 1 mediates nutritional immunity in <i>Drosophila melanogaster</i>.Proc Natl Acad Sci U S A2020
30993828Two Nimrod receptors, NimC1 and Eater, synergistically contribute to bacterial phagocytosis in Drosophila melanogaster.FEBS J2019
31781114Dynamic Evolution of Antimicrobial Peptides Underscores Trade-Offs Between Immunity and Ecological Fitness.Front Immunol2019
31735669Adult Drosophila Lack Hematopoiesis but Rely on a Blood Cell Reservoir at the Respiratory Epithelia to Relay Infection Signals to Surrounding Tissues.Dev Cell2019
31358113The antimicrobial peptide defensin cooperates with tumour necrosis factor to drive tumour cell death in <i>Drosophila</i>.Elife2019
31018123More Than Black or White: Melanization and Toll Share Regulatory Serine Proteases in Drosophila.Cell Rep2019
30953686Phagocytosis in Drosophila: From molecules and cellular machinery to physiology.Insect Biochem Mol Biol2019
30803481Synergy and remarkable specificity of antimicrobial peptides in vivo using a systematic knockout approach.Elife2019
30995484The Exchangeable Apolipoprotein Nplp2 Sustains Lipid Flow and Heat Acclimation in Drosophila.Cell Rep2019
31135338Correction: Synergy and remarkable specificity of antimicrobial peptides in vivo using a systematic knockout approach.Elife2019
30786854Functional analysis of RIP toxins from the Drosophila endosymbiont Spiroplasma poulsonii.BMC Microbiol2019
29559567<i>In Vitro</i> Culture of the Insect Endosymbiont <i>Spiroplasma poulsonii</i> Highlights Bacterial Genes Involved in Host-Symbiont Interaction.mBio2018
30287514Anatomy and Physiology of the Digestive Tract of Drosophila melanogaster.Genetics2018
30564440Evolution of longevity improves immunity in Drosophila.Evol Lett2018
30446385Microbiota-Derived Lactate Activates Production of Reactive Oxygen Species by the Intestinal NADPH Oxidase Nox and Shortens Drosophila Lifespan.Immunity2018
29752064Cell-Specific Imd-NF-κB Responses Enable Simultaneous Antibacterial Immunity and Intestinal Epithelial Cell Shedding upon Bacterial Infection.Immunity2018
29720654Male-killing toxin in a bacterial symbiont of Drosophila.Nature2018
29563258Common and unique strategies of male killing evolved in two distinct <i>Drosophila</i> symbionts.Proc Biol Sci2018
27923532Physiological Adaptations to Sugar Intake: New Paradigms from Drosophila melanogaster.Trends Endocrinol Metab2017
28079522Protection from within.Elife2017
28186693Science, narcissism and the quest for visibility.FEBS J2017
29084242Transforming Growth Factor β/Activin signaling in neurons increases susceptibility to starvation.PLoS One2017
29121087The gram-negative sensing receptor PGRP-LC contributes to grooming induction in Drosophila.PLoS One2017
28874153Thioester-containing proteins regulate the Toll pathway and play a role in Drosophila defence against microbial pathogens and parasitoid wasps.BMC Biol2017
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Collaborators

Jules A Hoffmann
Sino-French Hoffmann Institute, Guangzhou Medical University
Co-authored papers 14
Shu Kondo
Co-authored papers 14
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Oregon Health & Science University Hospital.
Co-authored papers 4
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The University of Florida
Co-authored papers 3
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CNRS, Aix-Marseille Universite
Co-authored papers 2
Johan Trygg
Co-authored papers 1
Iswar K Hariharan
University of California berkeley
Co-authored papers 1
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Precision Medicine Network Inc.
Co-authored papers 1
Mitchell D Miller
Rice University
Co-authored papers 1
Mark Yandell
University of Utah
Co-authored papers 1
Athanasios Typas
University of California san francisco
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Peter Brokstein
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Gregory D D Hurst
Institute of Infection, University of Liverpool
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University of California davis
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National Institutes of Allergy and Infectious Diseases
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University of Cambridge
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Institut Francois Jacob, CNRS, Universite d'Evry, Universite Paris-Saclay
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Jean Weissenbach
Institut Francois Jacob, CNRS, Universite Paris-Saclay
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Reed A George
Howard Hughes Medical Institute
Co-authored papers 1
George L Gabor Miklos
Monash University at Cabrini Health
Co-authored papers 1
Sylvain Pradervand
Co-authored papers 1
R F Galle
Co-authored papers 1
M P Skupski
National Center for Genome Resources
Co-authored papers 1
Susan E Celniker
Lawrence Berkeley National Laboratory
Co-authored papers 1
J Zhang
Co-authored papers 1
J Michael Cherry
Stanford University
Co-authored papers 1
Sima Misra
University of California berkeley
Co-authored papers 1
David Coates
University of Leeds
Co-authored papers 1
Release 1.2