Author details

Full Name

Neil P King

Affiliation

ORCID

Career Start Year

1998

Papers

102

H Index

Expertise

CM4AI Collaborator

PMID	Paper Title	Journal Title	Published Year
37503272	Hierarchical design of pseudosymmetric protein nanoparticles.	Res Sq	2023
37939083	In vivo selection of synthetic nucleocapsids for tissue targeting.	Proc Natl Acad Sci U S A	2023
37905007	Local structural flexibility drives oligomorphism in computationally designed protein assemblies.	bioRxiv	2023
37577608	Saponin Nanoparticle Adjuvants Incorporating Toll-Like Receptor Agonists Improve Vaccine Immunomodulation.	bioRxiv	2023
37577478	Rapid and automated design of two-component protein nanomaterials using ProteinMPNN.	bioRxiv	2023
37794071	Nanoparticle display of prefusion coronavirus spike elicits S1-focused cross-reactive antibody response against diverse coronavirus subgenera.	Nat Commun	2023
36593311	Computational design of constitutively active cGAS.		2023
36713406	Design and immunological evaluation of two-component protein nanoparticle vaccines for East Coast fever.	Front Immunol	2023
37020354	Progress in vaccine development for infectious diseases-a Keystone Symposia report.	Ann N Y Acad Sci	2023
36711543	Extremely potent pan-sarbecovirus neutralizing antibodies generated by immunization of macaques with an AS03-adjuvanted monovalent subunit vaccine against SARS-CoV-2.	bioRxiv	2023
37398374	Hierarchical design of pseudosymmetric protein nanoparticles.	bioRxiv	2023
37079676	Top-down design of protein architectures with reinforcement learning.	Science	2023
36888664	Improving the secretion of designed protein assemblies through negative design of cryptic transmembrane domains.	Proc Natl Acad Sci U S A	2023
37013198	Process development of a SARS-CoV-2 nanoparticle vaccine.		2023
37131615	Computational design of non-porous, pH-responsive antibody nanoparticles.	bioRxiv	2023
37364125	De novo designed ice-binding proteins from twist-constrained helices.		2023
37292995	Antigen spacing on protein nanoparticles influences antibody responses to vaccination.		2023
37292967	Combinatorial immune refocusing within the influenza hemagglutinin head elicits cross-neutralizing antibody responses.	bioRxiv	2023
37163615	Broadly neutralizing antibodies against sarbecoviruses generated by immunization of macaques with an AS03-adjuvanted COVID-19 vaccine.	Sci Transl Med	2023
35021101	Mannose-binding lectin and complement mediate follicular localization and enhanced immunogenicity of diverse protein nanoparticle immunogens.	Cell Rep	2022
36108050	Robust deep learning-based protein sequence design using ProteinMPNN.	Science	2022
35705092	Immunization with a self-assembling nanoparticle vaccine displaying EBV gH/gL protects humanized mice against lethal viral challenge.	Cell Reports Medicine	2022
35584193	Epitope-focused immunogen design based on the ebolavirus glycoprotein HR2-MPER region.	PLoS Pathog	2022
36036783	Correction: IgM antibodies derived from memory B cells are potent cross-variant neutralizers of SARS-CoV-2.	J Exp Med	2022
35446645	Computational design of mechanically coupled axle-rotor protein assemblies.	Science	2022
35383176	Structure-based design of stabilized recombinant influenza neuraminidase tetramers.	Nat Commun	2022
35879941	Safety and immunogenicity of a SARS-CoV-2 recombinant protein nanoparticle vaccine (GBP510) adjuvanted with AS03: A randomised, placebo-controlled, observer-blinded phase 1/2 trial.	eClinicalMedicine	2022
35938988	IgM antibodies derived from memory B cells are potent cross-variant neutralizers of SARS-CoV-2.	J Exp Med	2022
35487503	Engineering Self-Assembling Protein Nanoparticles for Therapeutic Delivery.	Bioconjugate Chemistry	2022
36206752	Antigen- and scaffold-specific antibody responses to protein nanoparticle immunogens.	Cell Reports Medicine	2022
35988541	Distinct sensitivities to SARS-CoV-2 variants in vaccinated humans and mice.	Cell Rep	2022
35606518	Adjuvanting a subunit SARS-CoV-2 vaccine with clinically relevant adjuvants induces durable protection in mice.	NPJ Vaccines	2022
36439375	Co-display of diverse spike proteins on nanoparticles broadens sarbecovirus neutralizing antibody responses.	iScience	2022
36434005	Induction of cross-neutralizing antibodies by a permuted hepatitis C virus glycoprotein nanoparticle vaccine candidate.	Nature Communications	2022
36380759	Nanoparticle display of prefusion coronavirus spike elicits S1-focused cross-reactive protection across divergent subgroups.	Res Sq	2022
35977542	Vaccination with a structure-based stabilized version of malarial antigen Pfs48/45 elicits ultra-potent transmission-blocking antibody responses.	Immunity	2022
35976993	Durable protection against the SARS-CoV-2 Omicron variant is induced by an adjuvanted subunit vaccine.	Sci Transl Med	2022
34525339	Limited access to antigen drives generation of early B cell memory while restraining the plasmablast response.	Immunity	2021
34230930	Qualification of ELISA and neutralization methodologies to measure SARS-CoV-2 humoral immunity using human clinical samples.		2021
33795432	Designed proteins assemble antibodies into modular nanocages.	Science	2021
33688647	Engineered SARS-CoV-2 receptor binding domain improves immunogenicity in mice and elicits protective immunity in hamsters.	bioRxiv	2021
33535236	Dynamics of Neutralizing Antibody Titers in the Months After Severe Acute Respiratory Syndrome Coronavirus 2 Infection.	J Infect Dis	2021
33577765	Two-component spike nanoparticle vaccine protects macaques from SARS-CoV-2 infection.	Cell	2021
33784513	Structure-based design of novel polyhedral protein nanomaterials.	Current Opinion in Microbiology	2021
34267764	Stabilization of the SARS-CoV-2 Spike Receptor-Binding Domain Using Deep Mutational Scanning and Structure-Based Design.	Front Immunol	2021
33563988	Complete and cooperative in vitro assembly of computationally designed self-assembling protein nanomaterials.	Nat Commun	2021
33563983	Immunofocusing and enhancing autologous Tier-2 HIV-1 neutralization by displaying Env trimers on two-component protein nanoparticles.	npj Vaccines	2021
33661302	Multimeric antibodies from antigen-specific human IgM+ memory B cells restrict Plasmodium parasites.	J Exp Med	2021
33873199	Adjuvanting a subunit COVID-19 vaccine to induce protective immunity.	Nature	2021
33762730	Quadrivalent influenza nanoparticle vaccines induce broad protection.	Nature	2021